Heart Failure
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-10-30Clinical Trial Update: Acetazolamide in Patients With Acute Heart Failure [Phase 3]
A Phase 3 clinical trial update on acetazolamide for patients with acute heart failure, with unclear status.
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FDA approval · 2018-10-29FDA Approved: METOPROLOL SUCCINATE — Supplemental Application (Zydus Pharmaceuticals (USA) Inc.)
The FDA approved a supplemental application for metoprolol succinate submitted by Zydus Pharmaceuticals (USA) Inc., updating the labeling fo…
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FDA approval · 2018-10-26FDA Approved: FARXIGA — Supplemental Application (AstraZeneca Pharmaceuticals LP)
FDA approved a supplemental application for Farxiga (dapagliflozin) from AstraZeneca Pharmaceuticals LP.
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CLINICAL_TRIALS trial_result · 2018-10-26Clinical Trial Update: Influenza Vaccine To Prevent Adverse Vascular Events (RCT-IVVE) [Phase 4]
Phase 4 randomized trial investigating whether influenza vaccination reduces adverse vascular events in patients with heart failure.
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CLINICAL_TRIALS trial_result · 2018-10-26Clinical Trial Update: Influenza Vaccine To Prevent Adverse Vascular Events:Pilot [Phase 4]
A Phase 4 clinical trial evaluating an influenza vaccine for prevention of adverse vascular events in patients with heart failure has comple…
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FDA approval · 2018-10-26FDA Approved: METOPROLOL SUCCINATE — Original Application (BluePoint Laboratories)
FDA approved a generic metoprolol succinate product from BluePoint Laboratories under an original ANDA for the treatment of hypertension, an…
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CLINICAL_TRIALS trial_result · 2018-10-22Clinical Trial Update: Sensitivity of the InSync Sentry OptiVol Feature for the Prediction of Heart Failure [NA]
The clinical trial evaluated the sensitivity of the InSync Sentry OptiVol feature in predicting heart failure events; results have been post…
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CLINICAL_TRIALS trial_result · 2018-10-17Clinical Trial Update: Oral dIuretics in Very Intensive Treatment, an Early Intervention in Outpatients With Heart Failure [Phase 4]
Phase 4 trial updating oral diuretics in very intensive outpatient treatment for heart failure; status and outcomes not specified in the sni…
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CLINICAL_TRIALS trial_result · 2018-10-16Clinical Trial Update: Prednisone for Heart Failure Patients With Hyperuricemia [Phase 2, Phase 3]
A phase 2/3 clinical trial explored prednisone for patients with heart failure and hyperuricemia; the study has completed.
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CLINICAL_TRIALS trial_result · 2018-10-16Clinical Trial Update: Adaptive Cardiac Resynchronization Therapy Study [NA]
A completed adaptive cardiac resynchronization therapy study with results posted in 2018.
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FDA approval · 2018-10-12FDA Approved: CHLORTHALIDONE — Original Application (Dr. Reddy's Laboratories Inc.)
FDA approved Dr. Reddy's Laboratories Inc.'s original application for chlorthalidone (generic diuretic) under ANDA210742.
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CLINICAL_TRIALS trial_result · 2018-10-09Clinical Trial Update: Balance Training for Elders With Heart Failure [NA]
A completed clinical trial evaluating balance training for elders with heart failure; results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-09-28Clinical Trial Update: The Effect of an Azygos Vein Coil on Defibrillation Threshold [NA]
A completed clinical trial investigated the effect of an azygos vein coil on defibrillation threshold in heart failure patients; results pos…
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CLINICAL_TRIALS trial_result · 2018-09-27Clinical Trial Update: A First Time in Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GSK2798745 in Healthy Subjects and Stable Heart Failure Patients [Phase 2]
Phase 2 first-time-in-human study evaluating safety, tolerability, PK and PD of GSK2798745 in healthy subjects and stable heart failure pati…
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CLINICAL_TRIALS trial_result · 2018-09-26Clinical Trial Update: High-Flow-Therapy for the Treatment of Cheyne-Stokes-Respiration in Chronic Heart Failure [Phase 3]
Phase 3 trial updating the use of high-flow therapy for Cheyne-Stokes respiration in chronic heart failure has been terminated.
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CLINICAL_TRIALS trial_result · 2018-09-21Clinical Trial Update: Study of the Effect of Serelaxin on High-sensitivity Cardiac Troponin I (Hs-cTnI) Release in Patients With Chronic Heart Failure [Phase 2]
Phase 2 trial studying serelaxin's effect on hs-cTnI release in chronic heart failure was terminated with results posted in 2018.
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FDA label_change · 2018-09-20FDA Approved: LANOXIN — Supplemental Application (Covis Pharma US, Inc)
The FDA approved a supplemental application for LANOXIN (digoxin) submitted by Covis Pharma US, Inc. The action updates the product labeling…
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CLINICAL_TRIALS trial_result · 2018-09-19Clinical Trial Update: Researching Emotions And Cardiac Health (REACH): Phase II [NA]
Phase II trial update for the REACH study investigating the relationship between emotions and cardiac health in congestive heart failure; re…
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CLINICAL_TRIALS trial_result · 2018-09-18Clinical Trial Update: Treatment of Severe Secondary TRIcuspid Regurgitation in Patients With Advance Heart Failure With CAval Vein Implantation of the Edwards Sapien XT VALve (TRICAVAL) [Phase 2, Phase 3]
A clinical trial investigating transcatheter valve implantation for severe tricuspid regurgitation in advanced heart failure was terminated …
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FDA approval · 2018-09-14FDA Approved: EPLERENONE — Original Application (Breckenridge Pharmaceutical, Inc.)
FDA approved Breckenridge Pharmaceutical's original ANDA for eplerenone (generic), a mineralocorticoid receptor antagonist used to treat hea…
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CLINICAL_TRIALS trial_result · 2018-09-05Clinical Trial Update: A Study to Evaluate the Effect of the Transient Receptor Potential Vanilloid 4 (TRPV4) Channel Blocker, GSK2798745, on Pulmonary Gas Transfer and Respiration in Patients With Congestive Heart Failure [Phase 2]
Phase 2 clinical trial evaluating TRPV4 blocker GSK2798745 for pulmonary gas transfer and respiration in heart failure; study completed with…
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CLINICAL_TRIALS trial_result · 2018-08-31Clinical Trial Update: The Use of CoSeal (Sealant Agent) in Patients During Left Ventricular Assist Device Surgery [NA]
Clinical trial update on the use of CoSeal sealant during left ventricular assist device surgery; the study has terminated with results post…
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FDA approval · 2018-08-24FDA Approved: DIGOXIN — Supplemental Application (Hikma Pharmaceuticals USA Inc.)
FDA approved a supplemental application for Digoxin (DIGOXIN) from Hikma Pharmaceuticals USA Inc.
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FDA label_change · 2018-08-24FDA Approved: LANOXIN — Supplemental Application (Covis Pharma US, Inc)
FDA approves a supplemental application for LANOXIN (digoxin) filed by Covis Pharma US, Inc., resulting in changes to the product labeling.
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CLINICAL_TRIALS trial_result · 2018-08-22Clinical Trial Update: Repetitive Levosimendan Infusion for Patients With Advanced Chronic Heart Failure [Phase 3]
Phase 3 clinical trial update on repetitive levosimendan infusion for patients with advanced chronic heart failure.