Heart Failure
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CLINICAL_TRIALS trial_result · 2015-10-12Clinical Trial Update: Monitoring of Fluid Status in Heart Failure Patients by Intrathoracic Impedance Measurement in Japan (J-HomeCARE II) [Phase 4]
A Phase 4 study (J-HomeCARE II) evaluating intrathoracic impedance monitoring to manage fluid status in heart failure patients in Japan has …
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CLINICAL_TRIALS trial_result · 2015-10-12Clinical Trial Update: The Effect of Liraglutide on Left Ventricular Function in Chronic Heart Failure Patients With and Without Type 2 Diabetes Mellitus [NA]
A completed clinical trial studied the effect of liraglutide on left ventricular function in chronic heart failure patients, with and withou…
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CLINICAL_TRIALS trial_result · 2015-10-12Clinical Trial Update: Study of Heart Failure Hospitalizations After Aquapheresis Therapy Compared to Intravenous (IV) Diuretic Treatment [NA]
Clinical trial update for aquapheresis versus IV diuretics in heart failure; study terminated with results posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-10-09Clinical Trial Update: Safety and Efficacy of Direct Blood Volume Measurement in the Treatment of Heart Failure [Phase 4]
A Phase 4 trial evaluating direct blood volume measurement for the treatment of heart failure was terminated.
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CLINICAL_TRIALS trial_result · 2015-10-08Clinical Trial Update: A Phase IIb Study to Investigate the Efficacy and Tolerability of Cinaciguat (150 µg/h, 100 µg/h, 50 µg/h) Given Intravenously to Subjects With Acute Decompensated Chronic Congestive Heart Failure (ADHF) [Phase 2]
A Phase IIb study evaluating intravenous Cinaciguat in patients with acute decompensated heart failure was terminated.
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CLINICAL_TRIALS trial_result · 2015-10-08Clinical Trial Update: Acute and Cronic Evaluation of AV/PV and VV Delay IEGM Based Optimisation Algorithm-QuickSept Study
A completed clinical trial evaluating AV/PV and VV delay optimization using the IEGM-based QuickSept algorithm in heart failure patients.
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CLINICAL_TRIALS trial_result · 2015-10-08Clinical Trial Update: 12-Week-Combined Physical Training In Heart Failure Patients [NA]
This entry reports the completion of a clinical trial evaluating 12-week combined physical training in heart failure patients.
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CLINICAL_TRIALS trial_result · 2015-10-08Clinical Trial Update: BAY58-2667 Dose Finding Trial Investigating Fixed Doses in Patients With Acute Decompensated Chronic Congestive Heart Failure (ADHF) [Phase 2]
A Phase 2 dose-finding trial of BAY58-2667 in patients with acute heart failure has been terminated. The study investigated fixed dosing in …
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CLINICAL_TRIALS trial_result · 2015-10-08Clinical Trial Update: Beta-2 Polymorphisms and Beta Receptor Selectivity [NA]
This clinical trial update notes a completed study exploring how beta-2 receptor polymorphisms influence beta receptor selectivity in heart …
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CLINICAL_TRIALS trial_result · 2015-10-05Clinical Trial Update: Patient-Centered Advance Care Planning [Phase 3]
A Phase 3 clinical trial on patient-centered advance care planning in patients with heart failure or renal failure has completed.
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CLINICAL_TRIALS trial_result · 2015-09-30Clinical Trial Update: Pacing Affects Cardiovascular Endpoints in Patients With Right Bundle-Branch Block (The PACE-RBBB Trial) [NA]
The PACE-RBBB trial evaluated pacing effects on cardiovascular endpoints in patients with right bundle-branch block and heart failure; the s…
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CLINICAL_TRIALS trial_result · 2015-09-28Clinical Trial Update: Can the Venus 1000 Help Clinicians Treat Patients With Severe Sepsis or Acute Heart Failure? The CVP Trial [NA]
This document reports an update on the CVP trial evaluating the Venus 1000 device for treating severe sepsis and acute heart failure, sponso…
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CLINICAL_TRIALS trial_result · 2015-09-25Clinical Trial Update: Response of Cardiac Resynchronization Therapy Optimization With Ventricle to Ventricle Timing in Heart Failure Patients [Phase 4]
Phase 4 clinical trial assessing optimization of cardiac resynchronization therapy using ventricle-to-ventricle timing in heart failure pati…
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CLINICAL_TRIALS trial_result · 2015-09-24Clinical Trial Update: To Evaluate the Efficacy and Safety on Blood Pressure In Patients With Hypertension Diagnosed Congestive Heart Failure [Phase 4]
This Clinical Trial Update reports on a Phase 4 study sponsored by Chong Kun Dang Pharmaceutical evaluating the efficacy and safety of a tre…
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CLINICAL_TRIALS trial_result · 2015-09-22Clinical Trial Update: The Influence of Different Training Regimens on Electrical Stability Following Myocardial Infarction [NA]
A completed clinical trial evaluated how different exercise training regimens after myocardial infarction affect electrical stability. The s…
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CLINICAL_TRIALS trial_result · 2015-09-22Clinical Trial Update: Nutritional Intervention Program in Malnourished Patients Admitted for Heart Failure [Phase 3]
Phase 3 nutritional intervention trial in malnourished patients hospitalized for heart failure has been terminated.
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CLINICAL_TRIALS trial_result · 2015-09-17Clinical Trial Update: A Study Investigating the Safety, Tolerability, and Pharmacokinetics of MTP-131 in Subjects With Congestive Heart Failure [Phase 1]
A Phase 1 clinical trial evaluated the safety, tolerability, and pharmacokinetics of MTP-131 in subjects with congestive heart failure; the …
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CLINICAL_TRIALS trial_result · 2015-09-17Clinical Trial Update: Nasal High Flow Therapy for the Treatment of Respiratory Insufficiencies During Sleep [NA]
The clinical trial evaluating nasal high-flow therapy for sleep-disordered breathing and heart failure was terminated, and results were post…
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CLINICAL_TRIALS trial_result · 2015-09-16Clinical Trial Update: Metabolic Changes in Patients With Chronic Cardiopulmonary Disease
This clinical trial update discusses metabolic changes in patients with chronic cardiopulmonary disease, including heart failure and chronic…
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CLINICAL_TRIALS trial_result · 2015-09-15Clinical Trial Update: Enhancing Caregiver Support for Heart Failure Patients: the CarePartner Study [NA]
A completed clinical trial (CarePartner Study) evaluated caregiver support for heart failure patients; results were posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-09-03Clinical Trial Update: Activity at Pulse Pressure Above an Individual Threshold in Patients With LVAD [NA]
A completed clinical trial update investigating activity when pulse pressure exceeds an individual threshold in patients with a left ventric…
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CLINICAL_TRIALS trial_result · 2015-09-02Clinical Trial Update: OneShot Renal Denervation Registry [Phase 2, Phase 3]
This document reports the termination of the OneShot Renal Denervation Registry trial (Phase 2/3). It was sponsored by Medtronic Endovascula…
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CLINICAL_TRIALS trial_result · 2015-08-25Clinical Trial Update: Effects of Air Pollution Exposure Reduction by Filter Mask on Heart Failure [NA]
This clinical trial update reports the completion of a study evaluating whether reducing air pollution exposure with a filter mask improves …
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CLINICAL_TRIALS trial_result · 2015-08-14Clinical Trial Update: GISSI-HF- Effects of n-3 PUFA and Rosuvastatin on Mortality-Morbidity of Patients With Symptomatic CHF [Phase 3]
Phase 3 trial evaluating the combined effects of omega-3 polyunsaturated fatty acids and rosuvastatin on mortality and morbidity in symptoma…
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CLINICAL_TRIALS trial_result · 2015-08-14Clinical Trial Update: Bi Treatment With Hydralazine/Nitrates Versus Placebo in Africans Admitted With Acute Heart Failure [Phase 3]
A Phase 3 trial evaluating hydralazine/isosorbide dinitrate versus placebo in African patients admitted with acute heart failure; the curren…