Heart Failure
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CLINICAL_TRIALS trial_result · 2023-11-30Clinical Trial Update: Metabolic Effects of Chronic Ketosis (KETO-CHF Metabolic) [Phase 2]
Phase 2 trial evaluating metabolic effects of chronic ketosis in heart failure has completed.
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CLINICAL_TRIALS trial_result · 2023-11-28Clinical Trial Update: Adaptive CRT Effect on Electrical Dyssynchrony [NA]
This clinical trial update reports results from NCT02543281, evaluating adaptive cardiac resynchronization therapy (CRT) and its effect on e…
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CLINICAL_TRIALS trial_result · 2023-11-22Clinical Trial Update: Treating Heart Failure With hiPSC-CMs [Phase 1, Phase 2]
A clinical trial update is reported for treating heart failure using hiPSC-derived cardiomyocytes, spanning Phase 1 and Phase 2, with an unk…
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CLINICAL_TRIALS trial_result · 2023-11-21Clinical Trial Update: SGLT2 Inhibitors in Patients With ADHF During Ventilator Weaning [Phase 3]
Phase 3 trial investigating SGLT2 inhibitors in patients with acute heart failure during ventilator weaning; currently recruiting.
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CLINICAL_TRIALS trial_result · 2023-11-15Clinical Trial Update: STARBRITE: A Randomized Pilot Trial of BNP-Guided Therapy in Patients With Advanced Heart Failure [Phase 2]
A Phase 2 randomized pilot trial evaluating BNP-guided therapy in patients with advanced congestive heart failure has completed.
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CLINICAL_TRIALS trial_result · 2023-11-09Clinical Trial Update: Hypertonic Saline Therapy in Ambulatory Heart Failure Unit. [Phase 3]
A Phase 3 trial evaluating hypertonic saline therapy for heart failure has completed, reporting results from ambulatory care settings.
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CLINICAL_TRIALS trial_result · 2023-11-08Clinical Trial Update: Pharmacodynamic Study of Carvedilol Versus Metoprolol in Heart Failure [Phase 4]
Phase 4 pharmacodynamic study comparing carvedilol to metoprolol in heart failure has completed.
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CLINICAL_TRIALS trial_result · 2023-10-24Clinical Trial Update: PARTNER 3 Trial - Mitral Valve in Valve [NA]
Edwards Lifesciences provides an update on the PARTNER 3 trial evaluating mitral valve-in-valve procedures for mitral valve disease. Results…
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CLINICAL_TRIALS trial_result · 2023-10-23Clinical Trial Update: A Multicenter Clinical Trial on DH001 Tablets in the Prevention of Doxorubicin-induced Cardiotoxicity in Cancer Patients [Phase 2]
Phase 2 multicenter trial evaluating DH001 tablets to prevent doxorubicin-induced cardiotoxicity in cancer patients; current status is unkno…
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CLINICAL_TRIALS trial_result · 2023-10-18Clinical Trial Update: The VALIDATE Study of Valsartan for Patients With Early Stage Heart Failure [Phase 4]
Phase 4 clinical trial update for valsartan in early stage heart failure and hypertension.
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CLINICAL_TRIALS trial_result · 2023-10-04Clinical Trial Update: Effect of Passive Exercise on Systemic Endothelial Function in Elderly Patients With Chronic Heart Failure [Phase 4]
Phase 4 trial evaluating the effect of passive exercise on systemic endothelial function in elderly patients with chronic heart failure has …
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CLINICAL_TRIALS trial_result · 2023-10-02Clinical Trial Update: Strategic MAnagement to Optimize Response To Cardiac Resynchronization Therapy Registry
A completed clinical trial registry update evaluating strategies to optimize response to cardiac resynchronization therapy in heart failure …
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CLINICAL_TRIALS trial_result · 2023-09-29Clinical Trial Update: Carvedilol in Preventing Heart Failure in Childhood Cancer Survivors [Phase 2]
A Phase 2 trial evaluating carvedilol to prevent heart failure in childhood cancer survivors has completed and results have been posted.
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CLINICAL_TRIALS trial_result · 2023-09-26Clinical Trial Update: The Effects of Ferric Derisomaltose in Patients With Acute Heart Failure and Iron Deficiency on Exercise Capacity and Quality of Life [Phase 4]
Phase 4 trial evaluating ferric derisomaltose for improving exercise capacity and quality of life in patients with acute heart failure and i…
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CLINICAL_TRIALS trial_result · 2023-09-11Clinical Trial Update: Study to Assess the Safety and Tolerability of IV Tonapofylline in Subjects With Acute Decompensated Heart Failure (ADHF) and Renal Insufficiency [Phase 3]
Phase 3 clinical trial update assessing safety and tolerability of intravenous tonapofylline in subjects with acute decompensated heart fail…
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CLINICAL_TRIALS trial_result · 2023-08-24Clinical Trial Update: C-Pulse IDE Feasibility Study- A Heart Assist System [NA]
Feasibility study results for the C-Pulse heart assist system in heart failure are completed with results posted.
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CLINICAL_TRIALS trial_result · 2023-08-22Clinical Trial Update: Asses the Anti-inflammatory Effects of Short Term Copaxone Therapy on Patients the Acute Decompensated Heart Failure [Phase 2]
Phase 2 clinical trial update evaluating short-term Copaxone therapy for anti-inflammatory effects in acute decompensated heart failure.
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CLINICAL_TRIALS trial_result · 2023-08-21Clinical Trial Update: Effects of Remote Patient Monitoring on Chronic Disease Management [NA]
Completed clinical trial examining the impact of remote patient monitoring on management of chronic diseases with results posted in 2023.
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CLINICAL_TRIALS trial_result · 2023-08-15Clinical Trial Update: The Effects of Ferric Derisomaltose in Patients With Acute Heart Failure and Iron Deficiency on Exercise Capacity and Quality of Life(COREVIVE-HFrEF) [Phase 4]
A Phase 4 clinical trial evaluating ferric derisomaltose for improving exercise capacity and quality of life in patients with acute heart fa…
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CLINICAL_TRIALS trial_result · 2023-08-08Clinical Trial Update: C-Pulse® System European Multicenter Study
Multicenter European study for the C-Pulse System in heart failure has completed and results were posted in 2023.
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CLINICAL_TRIALS trial_result · 2023-08-04Clinical Trial Update: Effect of Dapagliflozin in Patients With Acute Heart Failure (DAPA-RESPONSE-AHF) [Phase 2, Phase 3]
Phase 2/3 trial update investigating dapagliflozin for acute heart failure has completed.
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CLINICAL_TRIALS trial_result · 2023-08-01Clinical Trial Update: The Impact of Low Flow Nocturnal Oxygen Therapy on Hospital Admissions and Mortality in Patients With Heart Failure and Central Sleep Apnea [Phase 3]
Phase 3 trial assessing low flow nocturnal oxygen therapy in patients with heart failure and central sleep apnea was terminated; results pos…
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CLINICAL_TRIALS trial_result · 2023-08-01Clinical Trial Update: Efficacy of Oral Acetazolamide in Decongestion in Patients With Heart Failure [Phase 3]
A Phase 3 clinical trial update evaluating the efficacy of oral acetazolamide for decongestion in patients with heart failure. Status is cur…
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CLINICAL_TRIALS trial_result · 2023-08-01Clinical Trial Update: Avoiding Treatment in the Hospital With Furoscix for the Management of Congestion in Heart Failure - A Pilot Study [Phase 2]
A Phase 2 pilot study evaluating furoscix for avoiding hospitalization in heart failure patients with congestion has completed with results …
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CLINICAL_TRIALS trial_result · 2023-08-01Clinical Trial Update: Efficacy and Safety of ICD Remote Monitored Exercise Testing to Improve Heart Failure Outcomes: REMOTE HF-ACTION [NA]
A completed clinical trial evaluating remote monitored exercise testing for improving outcomes in heart failure, with results posted in 2023…