Heart Failure
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CLINICAL_TRIALS research · 2025-03-11Clinical Trial Update: A Study to Determine the Efficacy and Safety of Finerenone and SGLT2i in Combination in Hospitalized Patients with Heart Failure (CONFIRMATION-HF) [Phase 3]
A Phase 3 randomized trial (CONFIRMATION-HF) is evaluating the efficacy and safety of combining finerenone with a SGLT2 inhibitor in hospita…
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CLINICAL_TRIALS research · 2025-03-11Clinical Trial Update: A Study to Evaluate Finerenone on Clinical Efficacy and Safety in Patients with Heart Failure Who Are Intolerant or Not Eligible for Treatment with Steroidal Mineralocorticoid Receptor Antagonists [Phase 3]
Phase 3 clinical trial to evaluate the efficacy and safety of finerenone in heart failure patients who are intolerant or ineligible for ster…
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CLINICAL_TRIALS research · 2025-03-10Clinical Trial Update: LBBP as Initial Therapy in Patients With Non-ischemic Heart Failure and LBBB [NA]
A clinical trial is evaluating left bundle branch pacing as initial therapy for patients with non-ischemic heart failure and left bundle-bra…
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CLINICAL_TRIALS research · 2025-03-10Clinical Trial Update: EMPOWER-1: A Multi-site Clinical Cohort Research Study to Reduce Health Inequality
EMPOWER-1 is a multi-site cohort study sponsored by Future Genetics Limited aimed at reducing health inequality, focusing on cardiovascular …
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CLINICAL_TRIALS research · 2025-03-10Clinical Trial Update: Non-invasive Detection of Driveline Infections in Patients with a Left Ventricular Assist Device
A clinical trial is evaluating non-invasive methods to detect driveline infections in patients with an LVAD; the study is currently enrollin…
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CLINICAL_TRIALS research · 2025-03-07Clinical Trial Update: Investigating the Impact of Nudging Cardiologists to Prescribe Guideline-directed Medical Therapy in Heart Failure Patients [NA]
A clinical trial assessing whether nudging cardiologists to prescribe guideline-directed medical therapy affects prescribing practices in he…
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CLINICAL_TRIALS research · 2025-03-06Clinical Trial Update: Effect of Reduced Vasopressors on Mortality in ECMO-supported Cardiogenic Shock Patients
A ClinicalTrials.gov entry notes that a study evaluating whether reducing vasopressor use improves mortality in ECMO-supported cardiogenic s…
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CLINICAL_TRIALS research · 2025-03-04Clinical Trial Update: AI-based Prediction of Cardiac Function Using Echocardiography and Body Composition Data (ECHO-FIT Study)
A Yonsei University-sponsored clinical trial is evaluating AI-driven prediction of cardiac function from echocardiography and body compositi…
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CLINICAL_TRIALS research · 2025-03-04Clinical Trial Update: Surgical Ablation of AF Efficacy Trial [NA]
Clinical trial update on surgical ablation for atrial fibrillation; the study is currently recruiting.
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CLINICAL_TRIALS research · 2025-03-03Clinical Trial Update: The Türkiye Heart Failure Registry
Baskent University is recruiting for the Türkiye Heart Failure Registry to collect data on heart failure in Türkiye.
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CLINICAL_TRIALS research · 2025-03-03Clinical Trial Update: Naples Federico II Intensive Cardiac Care Unit Registry (Naples FED2-ICCU Registry)
This entry describes a registry for acute cardiovascular conditions at Naples Federico II University with recruiting status. It focuses on a…
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CLINICAL_TRIALS research · 2025-03-03Clinical Trial Update: Perioperative Interdisciplinary, Intersectoral Process Optimization in Heart Failure [NA]
Recruiting status for a perioperative interdisciplinary process optimization program in heart failure patients, sponsored by the University …
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CLINICAL_TRIALS research · 2025-02-28Clinical Trial Update: Heart Failure in Patients With Diabetes: Cells, Crosstalk and Consequences
A University of Leeds-led clinical trial is recruiting to study the cellular crosstalk and consequences of diabetes type 2 in patients with …
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CLINICAL_TRIALS research · 2025-02-25Clinical Trial Update: First in Human Clinical Investigation of the FIRE1 System in Heart Failure Patients (FUTURE-HF) [NA]
First-in-human investigation of the FIRE1 System for heart failure is underway. The trial is currently active but not recruiting.
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CLINICAL_TRIALS research · 2025-02-25Clinical Trial Update: Cardiac Autonomic Dysfunction As a Sign of Irreversible Advanced Heart Failure
This ClinicalTrials.gov entry reports a recruiting trial investigating cardiac autonomic dysfunction as a sign of irreversible advanced hear…
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CLINICAL_TRIALS research · 2025-02-25Clinical Trial Update: The Effect of Obesity and Weight Loss in Heart Failure With Reduced Ejection Fraction. [NA]
This clinical trial explores how obesity and weight loss influence outcomes in heart failure with reduced ejection fraction and is currently…
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CLINICAL_TRIALS research · 2025-02-24Clinical Trial Update: Synchrony in Cardiac Conduction: Assessing the Effects of Pacing on Cardiac Performance Through Magnetic Resonance Imaging and Advanced ECG-imaging [NA]
This clinical trial entry describes a study evaluating how cardiac pacing affects heart performance using MRI and advanced ECG imaging in pa…
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CLINICAL_TRIALS research · 2025-02-21Clinical Trial Update: Acute Response to Left Bundle Branch Area Pacing With SyncAV
A clinical trial sponsored by Abbott Medical Devices is evaluating the acute response to left bundle branch area pacing with SyncAV for hear…
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CLINICAL_TRIALS research · 2025-02-20Clinical Trial Update: Optimal Diuretic Therapies for Acute Heart Failure With Volume Overload [Phase 4]
Phase 4 clinical trial update focusing on optimal diuretic therapies for acute heart failure with volume overload; the study is currently re…
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CLINICAL_TRIALS research · 2025-02-20Clinical Trial Update: ChAracterization of Patients and Treatment OUtcomes in Severe Tricuspid Regurgitation
A clinical trial sponsored by the Medical University of Warsaw aims to characterize patient characteristics and treatment outcomes in severe…
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CLINICAL_TRIALS research · 2025-02-20Clinical Trial Update: Comparative Effectiveness of 7 Versus 21 Home-delivered Medically Tailored Meals to Improve Malnutrition Risk in Malnourished Patients With Heart Failure [NA]
This completed University of Pennsylvania–sponsored trial compares 7 versus 21 home-delivered medically tailored meals to reduce malnutritio…
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CLINICAL_TRIALS research · 2025-02-19Clinical Trial Update: The Effects of Low-Dose Versus High-Dose Intravenous IRON Therapy With Ferric DerisomaltOSE in Patients With Chronic Heart Failure and Iron Deficiency [Phase 4]
This update describes a Phase 4 clinical trial comparing low-dose versus high-dose intravenous ferric derisomaltose in patients with chronic…
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CLINICAL_TRIALS research · 2025-02-19Clinical Trial Update: Effect of Dapagliflozin in Myocardial Fibrosis and Ventricular Function in Patients With a ST-segment Elevation Myocardial Infarction [Phase 3]
Phase 3 trial update evaluating dapagliflozin for effects on myocardial fibrosis and ventricular function in patients after ST-segment eleva…
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CLINICAL_TRIALS research · 2025-02-19Clinical Trial Update: Efficacy of an Assisted Therapy Optimizing Module to Improve Physician Adherence [NA]
This entry reports an ongoing clinical trial evaluating an assisted therapy optimizing module aimed at improving physician adherence in hear…
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CLINICAL_TRIALS research · 2025-02-18Clinical Trial Update: Communication During Hospitalization About Resuscitation Trial [Phase 2, Phase 3]
An ongoing Phase 2/Phase 3 trial assesses communication about resuscitation preferences during hospitalization for patients with severe life…