Heart Failure
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036) [Phase 2, Phase 3]
Pediatric Phase 2/3 trial evaluating vericiguat for heart failure due to left ventricular systolic dysfunction, assessing efficacy, safety, …
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: CMP-MYTHiC Trial and Registry - CardioMyoPathy With MYocarditis THerapy With Colchicine [Phase 3]
A Phase 3 trial (CMP-MYTHiC) evaluating colchicine therapy for cardiomyopathy with myocarditis is currently recruiting. Sponsor: Niguarda Ho…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Real-world Study on Dapagliflozin Usage in Patients With Heart Failure (HF) in Germany
A real-world observational study evaluating dapagliflozin use in heart failure patients in Germany, currently active but not recruiting.
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Oral Carnitine in Heart Failure Patients [EARLY_Phase 1]
An early-phase study is evaluating oral L-carnitine in heart failure patients with suspected carnitine deficiency. The trial is currently re…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Cardiac Amyloidosis pRevaleNce of in OLDer Subjects Affected by Heart Failure
This clinical trial is currently recruiting older adults with cardiac amyloidosis to study the prevalence of the condition in people with he…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction [Phase 3]
A Phase 3 trial to evaluate finerenone versus placebo on standard treatment for safety, pharmacokinetics, and efficacy in children with hear…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction [Phase 3]
A Phase 3 clinical trial to evaluate long-term safety of finerenone in children and young adults with heart failure and left ventricular sys…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Evaluation of the BMPR2-Activin Signaling Pathway in Group II Pulmonary Hypertension.
A recruiting clinical trial at Hospital General Universitario Gregorio Marañon is evaluating the BMPR2-Activin signaling pathway in Group II…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: A Study to Learn More About the Safety of the Drug Vericiguat in Japanese People With Chronic Heart Failure Who Will be Receiving Vericiguat Under Real-world Conditions
This clinical trial update describes a study to assess the safety of vericiguat in Japanese patients with chronic heart failure under real-w…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Early Feasibility Study of the NORM™ System in Heart Failure Patients (FUTURE-HFII) [NA]
Clinical trial update indicating the FUTURE-HFII early feasibility study of the NORM System in heart failure patients is currently active bu…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: LUX-Dx TRENDS Evaluates Diagnostics Sensors in Heart Failure Patients Receiving Boston Scientific's Investigational ICM System. [NA]
Clinical trial update on LUX-Dx TRENDS evaluating diagnostic sensors in heart failure patients with Boston Scientific's investigational impl…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: Cardiogenic Shock Integrated PHenotyping for Event Reduction
An ongoing clinical trial at Niguarda Hospital is investigating cardiogenic shock integrated phenotyping to reduce adverse events in heart f…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: Comparative Study on the Mode of Action of Vicadrostat and Spironolactone on Protein Profiles and Renal Hemodynamic Effects (COMPARE-VS) [Phase 2]
Phase 2 clinical trial comparing Vicadrostat and spironolactone on protein profiles and renal hemodynamic effects in CKD and cardiovascular …
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: Echocardiographic Assessment of the Effect of Impella on Biventricular Function
This clinical trial update describes an echocardiographic assessment of the effect of the Impella heart pump on biventricular function in pa…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: III Brazilian Registry of Heart Failure
An entry in the clinical trial registry for the III Brazilian Registry of Heart Failure, sponsored by Hospital do Coração. The study is NOT_…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: A Study of Paramedic HF Management
Mayo Clinic is recruiting participants for a clinical study evaluating paramedics' management of heart failure.
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: Screening for Cardiac and Cardiac-associated Pathology Using Single-channel Electrocardiogram
This clinical trial update describes a study on screening for cardiac and cardiac-associated pathology using single-channel electrocardiogra…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart [Phase 3]
A Phase 3 trial to test Vicadrostat (BI-690517) in combination with empagliflozin for heart failure with reduced left ventricular function. …
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure [Phase 3]
A Phase 3 clinical trial is evaluating whether Vicadrostat in combination with Empagliflozin improves outcomes in people with heart failure …
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Acalabrutinib Monotherapy vs Investigator's Choice of Treatment in Patients With CL Leukaemia and Heart Failure [Phase 4]
This is a Phase 4 clinical trial comparing acalabrutinib monotherapy to investigator's choice of treatment in patients with chronic lymphocy…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Vascular Complications After Kidney Transplantation
ClinicalTrials.gov update from University of Aarhus shows recruiting status for a study on vascular complications following kidney transplan…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Factors Influencing Participation in PRADO and Telemedicine Interventions in Heart Failure
This update examines factors affecting enrollment in a heart failure trial that combines PRADO and telemedicine interventions. The study is …
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: BBAP With CS Mapping Guidance [NA]
A clinical trial update for BBAP with CS Mapping Guidance sponsored by Shanghai Zhongshan Hospital for heart failure; the study is currently…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Heart Failure Virtual Ward Research Study [NA]
A Heart Failure virtual ward research study sponsored by the National University of Ireland, Galway is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Advancing Clinical Heart Failure Outcomes Leveraging Defibrillation Lead Implant System for Left Bundle Branch Area Pacing [NA]
A Medtronic-sponsored clinical trial is evaluating a defibrillation lead implant system for left bundle branch area pacing to improve heart …