Heart Failure
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: Plasma ExtrAcellular RNAs and Biomarkers of Heart FaiLure During Decongestion: PEARL-HF Study
A trial update for the PEARL-HF study investigating plasma extracellular RNAs and biomarkers in heart failure during decongestion; the study…
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: A Trial of SHR-4658 in Healthy Volunteers or Volunteers With Elevated Blood Pressure [Phase 1]
Phase 1 trial of SHR-4658 sponsored by Beijing Suncadia Pharmaceuticals Co., Ltd, evaluating in healthy volunteers or volunteers with elevat…
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: The Effects of IL-1 Blockade on Inotrope Sensitivity in Patients With Heart Failure (AID-HEART) [Phase 1]
Phase 1 clinical trial investigating the effects of IL-1 blockade on inotrope sensitivity in patients with heart failure (AID-HEART) is curr…
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CLINICAL_TRIALS research · 2025-11-14Clinical Trial Update: Routine Validation and Reproducibility Testing of Laboratory Assays and Research Techniques Used for Endocrine, Cardiometabolic, and Musculoskeletal Disorder Research (VALD)
This clinical trial update describes routine validation and reproducibility testing of laboratory assays and techniques used in endocrine, c…
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CLINICAL_TRIALS research · 2025-11-13Clinical Trial Update: Supporting Health in Veterans With Heart Failure [NA]
Florida State University is recruiting veterans with heart failure for a clinical trial to study health outcomes. The update indicates the s…
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CLINICAL_TRIALS research · 2025-11-13Clinical Trial Update: Care Transitions App for Patients With Multiple Chronic Conditions [NA]
A clinical trial update for a care transitions mobile app intended for patients with multiple chronic conditions; the study is currently rec…
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CLINICAL_TRIALS research · 2025-11-13Clinical Trial Update: Salivary Extracellular Vesicle Associated lncRNAs in Heart Failure (SEAL-HF)
The SEAL-HF trial (NCT06169540) at Massachusetts General Hospital is evaluating salivary extracellular vesicle associated lncRNAs as biomark…
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CLINICAL_TRIALS research · 2025-11-13Clinical Trial Update: Impact of Vericiguat on Hemodynamics of Heart Failure [Phase 4]
Phase 4 trial assessing the impact of vericiguat on hemodynamics in heart failure, currently active but not recruiting.
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CLINICAL_TRIALS research · 2025-11-13Clinical Trial Update: A Trial Comparing High-Flow Nasal Cannula Versus Noninvasive Ventilation on Reintubation and Post-Extubation Respiratory Failure in High-Risk Patients With Systolic Heart Failure [NA]
A Yale University–sponsored clinical trial is comparing high-flow nasal cannula to noninvasive ventilation for preventing reintubation and p…
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CLINICAL_TRIALS research · 2025-11-12Clinical Trial Update: Fluid Guided Heart Failure Treatment at the Cleveland Clinic [NA]
A clinical trial update from Bodyport Inc. on fluid-guided treatment for heart failure at the Cleveland Clinic, currently recruiting.
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CLINICAL_TRIALS research · 2025-11-12Clinical Trial Update: Eat Well Heart Failure [NA]
Duke University is recruiting participants for a clinical trial called Eat Well Heart Failure focused on chronic heart failure.
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: UPBEAT: Using Polygenic Scores to Guide BB Therapy in HF With Mildly Reduced EF [NA]
This is an update for a trial that aims to guide beta-blocker therapy in heart failure with mildly reduced ejection fraction using polygenic…
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CLINICAL_TRIALS research · 2025-11-05Clinical Trial Update: CGM Use in Heart Failure [NA]
Emory University is conducting a clinical trial to evaluate the use of continuous glucose monitoring in patients with heart failure and diab…
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CLINICAL_TRIALS research · 2025-11-04Clinical Trial Update: The HEARTFELT Study [NA]
The HEARTFELT study is currently recruiting for heart failure and chronic heart failure, sponsored by Heartfelt Technologies.
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CLINICAL_TRIALS research · 2025-10-31Clinical Trial Update: Enhanced Nutritional Optimization in LVAD Trial [NA]
This clinical trial update describes an ongoing study evaluating enhanced nutritional optimization in patients with heart failure who have l…
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CLINICAL_TRIALS research · 2025-10-30Clinical Trial Update: Evaluation of Liver Stiffness Performance, by FibroScan®, to Detect Elevated Central Venous Pressure (CVP) [NA]
Clinical trial update describes evaluating liver stiffness using FibroScan to detect elevated central venous pressure in patients with heart…
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CLINICAL_TRIALS research · 2025-10-29Clinical Trial Update: Cleveland Heart and Metabolic Prevention Study
The Cleveland Heart and Metabolic Prevention Study sponsored by The Cleveland Clinic is currently ACTIVE_NOT_RECRUITING, focusing on heart f…
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CLINICAL_TRIALS research · 2025-10-23Clinical Trial Update: A Preliminary Study for INFORMED [Phase 4]
Phase 4 clinical trial update for INFORMED, an ongoing study led by Weill Medical College of Cornell University, currently enrolling by invi…
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CLINICAL_TRIALS research · 2025-10-22Clinical Trial Update: CSP #2025 - Geriatric OUt-of-hospital Randomized MEal Trial in Heart Failure: Veterans Affairs (GOURMET-VA) [NA]
This is a VA-sponsored clinical trial update for the GOURMET-VA study, a geriatric out-of-hospital randomized meal intervention targeting he…
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CLINICAL_TRIALS research · 2025-10-20Clinical Trial Update: Personalized Therapy Study - HFRS (TriageHF) Post Approval Study
Post-approval study update for Medtronic's HFRS (TriageHF) personalized therapy in heart failure; the study is currently active but not recr…
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CLINICAL_TRIALS research · 2025-10-20Clinical Trial Update: Use of Artificial Intelligence-Guided Echocardiography to assIst cardiovascuLar Patient managEment [NA]
Clinical trial update on using artificial intelligence-guided echocardiography to assist management of heart failure and valvular heart dise…
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CLINICAL_TRIALS research · 2025-10-14Clinical Trial Update: PAtient Similarity for Decision-Making in Prevention of Cardiovascular Toxicity (PACT): A Feasibility Study
This feasibility study evaluates using patient similarity to support decision-making in preventing cardiovascular toxicity.
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CLINICAL_TRIALS research · 2025-10-08Clinical Trial Update: An Observational Study to Learn More About the Real-world Outcomes in Patients With Heart Failure Who Initiate Treatment With Vericiguat in Japan
An observational real-world study in Japan examining outcomes for patients with chronic heart failure who start vericiguat treatment.
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CLINICAL_TRIALS research · 2025-10-08Clinical Trial Update: Methamphetamine Use Disorder Support in Heart Failure Pilot Study [NA]
USC is conducting a pilot study to support methamphetamine use disorder in patients with heart failure; recruitment has not yet started.
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CLINICAL_TRIALS research · 2025-10-07Clinical Trial Update: Exploring Water-free Sodium Storage [NA]
A Yale University-sponsored clinical trial on water-free sodium storage is currently recruiting, investigating potential implications for pa…