Heart Failure
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: Human/Machine Interface: What the HeartMate 3 ® Device Tells Us About the Future
A ClinicalTrials.gov entry for a HeartMate 3 left ventricular assist device study investigates the human/machine interface and related patie…
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: Myocardial Dysfunction Evaluation in Lower Extremity Arterial Disease Patients With Deformation Analysis
This clinical trial update outlines a study evaluating myocardial dysfunction in patients with peripheral artery disease, using deformation …
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: Depressive Symptoms, Cognitive Impairment, and Outcomes in Hospitalized Chronic Heart Failure Patients
An ongoing clinical trial sponsored by the Lithuanian University of Health Sciences is evaluating depressive symptoms, cognitive impairment,…
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: QUAD-HF - Prospective Registry of Patients With Incident Heart Failure and Left Ventricular Ejection Fraction <50%
This entry describes the QUAD-HF prospective registry of patients with incident heart failure and left ventricular ejection fraction <50%. R…
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: Remote Ischemic Preconditioning for Renal and Cardiac Protection in Congestive Heart Failure (RICH) Trial [Phase 2, Phase 3]
A Phase 2/Phase 3 clinical trial (RICH) is recruiting to evaluate remote ischemic preconditioning for renal and cardiac protection in patien…
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: heaRtInsiGHT Alert guIDE: RightAIDE Application of the HeartInsight Acute Heart Failure Predictor in Routine Clinical Practice: Organizational Models and Workflow.
A clinical trial update describing the implementation of the HeartInsight Acute Heart Failure Predictor in routine practice, focusing on org…
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: ENAVOgliflozin Outcome Trial in Patients With Severe Aortic Stenosis After Transcatheter Aortic Valve Replacement [Phase 4]
A Phase 4 trial evaluating ENAVOgliflozin in patients with severe aortic stenosis after transcatheter aortic valve replacement is currently …
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: Preparatory Work for a Trial of Adjuncts to Diuretic Treatment in Patients Hospitalised With Heart Failure: Addressing Uncertainties and Building Consensus
This document outlines preparatory work for a trial of adjuncts to diuretic treatment in hospitalized heart failure patients. It focuses on …
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CLINICAL_TRIALS research · 2025-12-12Clinical Trial Update: Evaluation of Heart Failure Telemonitoring Eligibility Criteria
This clinical trial update describes evaluating eligibility criteria for a telemonitoring program in heart failure patients and indicates th…
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CLINICAL_TRIALS research · 2025-12-12Clinical Trial Update: Nurse-Led Education for Heart Failure Self-Care and Stability [NA]
This clinical trial investigates nurse-led education to improve self-care and stability in people with chronic heart failure. The study is c…
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CLINICAL_TRIALS research · 2025-12-11Clinical Trial Update: Impact of Iron Deficiency on Arrhythmic Events and Resting ECG Abnormalities in Patients Hospitalized With Heart Failure
This registry entry describes a study evaluating the impact of iron deficiency on arrhythmic events and resting ECG abnormalities in patient…
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: Oxygen Targets in Acute Heart Failure With Pulmonary Congestion [Phase 2, Phase 3]
A Phase 2/3 clinical trial evaluating oxygen targets in patients with acute heart failure and pulmonary congestion is currently recruiting.
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: Cardiac point-of Care Ultrasound Training Pathway for Emergency Department Advanced Practice Providers [NA]
A clinical trial update indicates a Cardiac Point-of-Care Ultrasound training pathway for emergency department advanced practice providers i…
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: iCaReMe Global Registry
AstraZeneca's iCaReMe Global Registry is currently recruiting participants for a study covering Type 2 diabetes mellitus, hypertension, chro…
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: Myocardial Protection in Patients With Post-acute Inflammatory Cardiac Involvement Due to COVID-19 [Phase 3]
A Phase 3 clinical trial evaluating myocardial protection in patients with post-acute inflammatory cardiac involvement due to COVID-19 is cu…
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: Finerenone and Cardiac Remodeling [Phase 3]
A Phase 3 trial update for finerenone investigating its effects on cardiac remodeling in heart failure. The study is currently not recruitin…
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: Effect of Roxadustat on Heart Failure Patients With Anaemia and Moderate-to-Severe Chronic Kidney Disease
A clinical trial evaluating roxadustat in heart failure patients with anemia and moderate-to-severe chronic kidney disease; the study is not…
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: Surgical Versus Percutaneous Revascularization in Patients With Reduced Left Ventricular Function (STICH 3.0-NL) [NA]
STICH 3.0-NL is a clinical trial comparing surgical versus percutaneous revascularization in patients with reduced left ventricular function…
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: Left Bundle Branch Area Pacing (LBBAP) Monitoring Assistant: Evaluation of Portable ECG Solution [NA]
An ongoing clinical trial evaluating a portable ECG monitoring solution for patients undergoing Left Bundle Branch Area Pacing to support ma…
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: A Research Study on the Effects of NNC0537-1482 in Participants With Heart Failure [Phase 1]
Phase 1 clinical trial evaluating the effects of NNC0537-1482 in participants with heart failure; currently recruiting.
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: Comparison Between a Robotic Tele-echo-cardiography Technique and a Standard Echocardiography in the Management of Heart Failure in the Guadeloupe Archipelago Between the University Hospital of Guadeloupe and the Marie-Galante Hospital [NA]
A clinical trial evaluating robotic tele-echo-cardiography versus standard echocardiography for managing heart failure in the Guadeloupe arc…
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Effects of Early Cardiopulmonary Rehabilitation in Patients With Acute Decompensated Heart Failure [NA]
A clinical trial is recruiting to evaluate the effects of early cardiopulmonary rehabilitation in patients with acute decompensated heart fa…
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: The RENAL LIFECYCLE Trial: A RCT to Assess the Effect of Dapagliflozin on Renal and Cardiovascular Outcomes in Patients With Severe CKD [Phase 3]
This is a Phase 3 randomized trial update evaluating dapagliflozin for renal and cardiovascular outcomes in patients with severe chronic kid…
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: Phosphatase Inhibition by Intracoronary Gene Therapy in Subjects With Non-Ischemic NYHA Class III Heart Failure [Phase 2]
Phase 2 trial update evaluating phosphatase-inhibiting intracoronary gene therapy in subjects with non-ischemic NYHA Class III heart failure…
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: Echocardiography in Nursing Home [NA]
A clinical trial update indicates that Nantes University Hospital is recruiting to study the use of echocardiography in nursing home residen…