Heart Failure with Reduced Ejection Fraction
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Heart Failure Management for Patient With CIED Remotely Monitored [NA]
A clinical trial update indicates a study on heart failure management for patients with remotely monitored cardiac implanted electronic devi…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Synchronized Diaphragmatic Stimulation in Symptomatic Heart Failure [NA]
A clinical trial evaluating synchronized diaphragmatic stimulation for heart failure with reduced ejection fraction is currently recruiting.…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Pharmacological Optimization in Prevention in Heart Failure: A Sex-gap? [Phase 4]
An update on a Phase 4 trial evaluating pharmacological optimization to prevent heart failure, including consideration of sex differences; r…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Efficacy and Safety of Sacubitril/Valsartan in African American Patients With Heart Failure With Reduced Ejection Fraction
A completed clinical trial assessed the efficacy and safety of sacubitril/valsartan in African American patients with heart failure with red…
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CLINICAL_TRIALS trial_result · 2026-03-25Clinical Trial Update: Sodium-Glucose Cotransporter 2 Inhibitor Use in a National Heart Failure Telemonitoring Program
This clinical trial update reports the completion of a national telemonitoring program evaluating the use of SGLT2 inhibitors in heart failu…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Propensity-Matched Study of Cardiac Contractility Modulation Therapy in Heart Failure
A clinical trial update describes a propensity-matched analysis of cardiac contractility modulation therapy in patients with heart failure w…
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CLINICAL_TRIALS trial_result · 2026-03-16Clinical Trial Update: Effect of Vericiguat on cardiAc Remodeling in Patients With Heart faiLure and Reduced Ejection fractioN (HFrEF): A Prospective sTudy usIng NOvel Echocardiographic Imaging Techniques (VALENTINO)
This completed clinical trial evaluates the effect of vericiguat on cardiac remodeling in patients with heart failure with reduced ejection …
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Effectiveness of Video Monitoring and Care Transition for Heart Failure Patients (EVIT-HF): Randomized Clinical Trial [NA]
This document describes a randomized clinical trial (EVIT-HF) evaluating video monitoring and care transition for patients with heart failur…
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CLINICAL_TRIALS trial_result · 2026-03-13Clinical Trial Update: BIOmarker Based Diagnostic TOOLkit to Personalize Pharmacological Approaches in Congestive Heart Failure
A completed clinical trial evaluating a biomarker-based diagnostic toolkit to personalize pharmacological therapy for heart failure, includi…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: Ketones in Heart Failure With Reduced Ejection Fraction [Phase 2]
Phase 2 clinical trial evaluating ketone-based therapy for heart failure with reduced ejection fraction; enrollment is currently by invitati…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: THE RELATIONSHIP BETWEEN CARDIAC RESYNCHRONİZATION THERAPY RESPONSE IN HEART FAILURE PATIENTS AND YKL-40 LEVELS
This clinical trial update from Trakya University describes an ongoing study investigating the relationship between response to cardiac resy…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: A Real-world Study of Clinical Treatment Guidelines for Patients With Heart Failure With Reduced Ejection Fraction Treated With Sacubitril/Valsartan
A real-world study evaluating how current clinical treatment guidelines guide the use of sacubitril/valsartan in patients with heart failure…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: A Randomized Placebo-procedure Controlled Trial of the Enhancor System (PULmonary Artery Denervation) to Evaluate Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart Disease [NA]
Clinical trial update for a randomized study evaluating the Enhancor System, a pulmonary artery denervation device, in patients with combine…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Evaluation of the Effects of Sauna Therapy on Congestion and Loop Diuretic Use in Patients With Heart Failure With Reduced or Moderately Reduced Ejection Fraction [NA]
Registry entry for a clinical trial evaluating sauna therapy to reduce congestion and loop diuretic use in patients with heart failure with …
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Infusing Needed Iron to Target Insufficiency in Adults Treated for Evidence of Heart Failure [NA]
This Kaiser Permanente trial tests intravenous iron to treat iron deficiency in adults with evidence of heart failure and its subtypes; the …
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: AI-Based Monitoring System for Chronic Heart Failure With Advanced Wearable and Mini-Invasive Devices
A clinical trial is evaluating an AI-based monitoring system for chronic heart failure using wearable and mini-invasive devices. The study i…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: Prospective Evaluation of AI-ECG for SHD Detection
Imperial College London is conducting a prospective study to evaluate an AI-enabled ECG for detecting structural heart disease; the trial is…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Real-Time Monitoring of Heart Failure Across the Yale New Haven Health System
A real-time heart failure monitoring clinical trial across Yale New Haven Health System is currently recruiting participants, focusing on he…
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CLINICAL_TRIALS withdrawal · 2026-03-04Clinical Trial Update: Effects of CRT Optimization as Assessed by Cardiac MR [NA]
A clinical trial evaluating optimization of cardiac resynchronization therapy (CRT) using cardiac magnetic resonance imaging was withdrawn, …
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Exercise Rehabilitation for Cardiorenal Syndrome in HFrEF Patients [NA]
ClinicalTrials.gov entry notes an ongoing trial examining exercise rehabilitation for patients with cardiorenal syndrome in the setting of h…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Digital Support Program for Patients With Heart Failure - a Cluster-Randomized Hybrid Type 2 Study [NA]
A cluster-randomized hybrid Type 2 study is evaluating a digital support program for patients with heart failure with reduced ejection fract…
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: Comparing Three Types of Specialist Pacemakers to Improve Heart Function and Reduce Rhythm Problems in Heart Failure [NA]
A clinical trial comparing three types of specialist pacemakers to improve heart function and reduce rhythm problems in people with heart fa…
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: Swedish Cardiac And Renal Failure Study-1 [Phase 2]
A Phase 2 clinical trial named Swedish Cardiac And Renal Failure Study-1 is currently recruiting, studying treatments for heart failure with…
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CLINICAL_TRIALS withdrawal · 2026-02-23Clinical Trial Update: Withdrawal of Treatment for Heart Failure Patients With Recovery From Tachycardia-induced Cardiomyopathy [Phase 2, Phase 3]
A clinical trial update regarding withdrawing treatment in heart failure patients who have recovered from tachycardia-induced cardiomyopathy…
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: London Valvular Heart Disease and Reduced Ejection Fraction Detection in a Multi-ethnic Community Using Cardiac Ultrasound
This recruiting study, led by Queen Mary University of London, aims to detect heart valve disease and reduced ejection fraction in a multi-e…