Heart Failure with Preserved Ejection Fraction
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CLINICAL_TRIALS trial_result · 2024-08-06Clinical Trial Update: Efficacy and Safety of LCZ696 Compared to Valsartan on Cognitive Function in Patients With Chronic Heart Failure and Preserved Ejection Fraction [Phase 3]
Phase 3 trial comparing LCZ696 (sacubitril/valsartan) to valsartan on cognitive function in patients with chronic heart failure with preserv…
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CLINICAL_TRIALS research · 2024-08-01Clinical Trial Update: Clinical Study of Active Intervention in High-risk HFpEF Patients [NA]
This entry outlines a clinical study evaluating an active intervention for high-risk heart failure with preserved ejection fraction (HFpEF),…
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CLINICAL_TRIALS trial_result · 2024-07-29Clinical Trial Update: Changes in NT-proBNP, Safety, and Tolerability in HFpEF Patients With a WHF Event (HFpEF Decompensation) Who Have Been Stabilized and Initiated at the Time of or Within 30 Days Post-decompensation (PARAGLIDE-HF) [Phase 3]
Phase 3 trial PARAGLIDE-HF in heart failure with preserved ejection fraction patients after decompensation reports NT-proBNP changes, safety…
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CLINICAL_TRIALS trial_result · 2024-07-25Clinical Trial Update: Regression of Fibrosis & Reversal of Diastolic Dysfunction in HFpEF Patients Treated With Allogeneic CDCs [Phase 2]
Phase 2 trial shows regression of fibrosis and reversal of diastolic dysfunction in heart failure with preserved ejection fraction after tre…
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CLINICAL_TRIALS trial_result · 2024-07-24Clinical Trial Update: Ketogenic Diet in Patients With Heart Failure [NA]
A clinical trial at Ohio State University evaluating a ketogenic diet in patients with heart failure with preserved ejection fraction has be…
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CLINICAL_TRIALS research · 2024-07-23Clinical Trial Update: Exercise Magnetic Resonance Imaging in Patients With Obesity Associated Heart Failure
A clinical trial assessing exercise-based magnetic resonance imaging in patients with obesity-associated heart failure with preserved ejecti…
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CLINICAL_TRIALS trial_result · 2024-07-19Clinical Trial Update: Global Prevalence of ATTR-CM in Participants With HFpEF [NA]
Pfizer-sponsored clinical trial evaluating how common transthyretin amyloid cardiomyopathy is among people with heart failure with preserved…
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CLINICAL_TRIALS research · 2024-07-19Clinical Trial Update: Dapagliflozin in Reducing Epicardial Adipose Tissue in Heart Failure with Preserved Ejection Fraction [NA]
This clinical trial is investigating whether dapagliflozin can reduce epicardial adipose tissue in heart failure with preserved ejection fra…
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CLINICAL_TRIALS research · 2024-07-18Clinical Trial Update: Pacing in Heart Failure With Preserved LVEF [NA]
This clinical trial update notes that enrollment is ongoing by invitation for a study evaluating pacing in heart failure with preserved ejec…
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CLINICAL_TRIALS research · 2024-07-17Clinical Trial Update: Renal Denervation to Treat Heart Failure With Preserved Ejection Fraction [NA]
This clinical trial update indicates that the University of Leipzig is recruiting to evaluate renal denervation as a treatment for heart fai…
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CLINICAL_TRIALS trial_result · 2024-07-08Clinical Trial Update: Risk Factors In Heart Failure Patients With Preserved Ejection Fraction
A completed clinical trial from Xiangtan Central Hospital examines risk factors associated with heart failure with preserved ejection fracti…
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CLINICAL_TRIALS research · 2024-07-05Clinical Trial Update: Cardiac Amyloidosis in HFpEF
This is a clinical trial update from National Taiwan University Hospital about cardiac amyloidosis in patients with heart failure with prese…
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CLINICAL_TRIALS trial_result · 2024-07-03Clinical Trial Update: Unsaturated Fatty Acids to Improve Cardiorespiratory Fitness in Obesity and HFpEF [NA]
The registry entry notes the completion of a trial studying unsaturated fatty acids to improve cardiorespiratory fitness in obesity and hear…
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CLINICAL_TRIALS research · 2024-07-03Clinical Trial Update: Application of Multimodal Large Language Model in HFpEF
An ongoing study from Peking University Third Hospital is recruiting to evaluate multimodal large language model applications in heart failu…
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CLINICAL_TRIALS research · 2024-07-03Clinical Trial Update: Investigating Multimodally Endothelial Dysfunction in Ocular and Systemic Disease [NA]
A clinical trial investigating multimodal endothelial dysfunction in ocular and systemic disease, including kidney diseases, diastolic heart…
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CLINICAL_TRIALS research · 2024-06-20Clinical Trial Update: Mechanistic Insights From Temporary Pacing in HFpEF [NA]
A clinical trial update from Guy's and St Thomas' NHS Foundation Trust describes a mechanistic study using temporary pacing in heart failure…
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CLINICAL_TRIALS research · 2024-06-17Clinical Trial Update: Feasibility Study to Support Cardiorenal Function in Acute Decompensated Heart Failure With Diuretic Resistance [NA]
Puzzle Medical Devices is conducting a feasibility study to support cardiorenal function in acute decompensated heart failure with diuretic …
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CLINICAL_TRIALS trial_result · 2024-06-07Clinical Trial Update: Oral Nitrite in Patients With Pulmonary Hypertension and Heart Failure With Preserved Ejection Fraction [Phase 2]
A Phase 2 study evaluating oral nitrite in patients with pulmonary hypertension and heart failure with preserved ejection fraction has compl…
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CLINICAL_TRIALS research · 2024-06-06Clinical Trial Update: SGLT-2 Inhibitor and High-Dose Furosemide Plus Small-Volume Hypertonic Saline Solution in Acute HF [Phase 4]
A Phase 4 clinical trial update investigating an SGLT-2 inhibitor combined with high-dose furosemide and small-volume hypertonic saline in p…
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CLINICAL_TRIALS withdrawal · 2024-06-03Clinical Trial Update: Rivet PVS Therapy in Group 2 PH-HFpEF Canada [NA]
The Rivet PVS Therapy trial in Group 2 pulmonary hypertension associated with heart failure with preserved ejection fraction (HFpEF) in Cana…
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CLINICAL_TRIALS trial_result · 2024-05-31Clinical Trial Update: Effect of IV Iron in Patients With Heart Failure With Preserved Ejection Fraction [Phase 4]
A Phase 4 clinical trial evaluating intravenous iron for iron deficiency in patients with heart failure with preserved ejection fraction has…
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CLINICAL_TRIALS research · 2024-05-23Clinical Trial Update: Treatment Of Atrial Fibrillation In Preserved Cardiac Function Heart Failure [Phase 4]
A Phase 4 clinical trial is currently recruiting to evaluate strategies for treating atrial fibrillation in patients with heart failure with…
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CLINICAL_TRIALS trial_result · 2024-05-17Clinical Trial Update: Study for the Treatment of Heart Failure With Preserved Ejection Fraction Associated With High Blood Pressure Using Right Atrial Pacing Controlled by the PressurePaceTM System [NA]
A BaroPace Inc. clinical trial evaluating the PressurePace System for treating heart failure with preserved ejection fraction associated wit…
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CLINICAL_TRIALS trial_result · 2024-05-16Clinical Trial Update: Efficacy of an m-Health Cardiac Rehabilitation Program in Heart Failure With Preserved Ejection Fraction [NA]
A completed clinical trial evaluates the efficacy of a mobile-health cardiac rehabilitation program for heart failure with preserved ejectio…
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CLINICAL_TRIALS research · 2024-05-16Clinical Trial Update: Value of Intense Phenotyping in Heart Failure With Preserved Ejection Fraction
This clinical trial update describes a study on the value of intense phenotyping in heart failure with preserved ejection fraction, currentl…