Heart Failure with Preserved Ejection Fraction
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-01-27Clinical Trial Update: Predicting Heart Failure Outcomes With Biomarkers and Imaging
A completed clinical trial evaluating whether circulating biomarkers and imaging findings can predict outcomes across different forms of hea…
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CLINICAL_TRIALS trial_result · 2026-01-08Clinical Trial Update: Mangafodipir - an Intracellular Contrast Agent for Magnetic Resonance Imaging (MRI): Measuring Manganese Uptake Rate in Heart Failure Patients With Preserved Ejection Fraction (HFpEF) Patients. [Phase 2]
A Phase 2 trial evaluated mangafodipir as an intracellular MRI contrast agent by measuring manganese uptake in patients with heart failure w…
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CLINICAL_TRIALS trial_result · 2025-12-29Clinical Trial Update: Enavogliflozin Outcome Trial in Functional Tricuspid Regurgitation [Phase 3]
Phase 3 trial evaluating enavogliflozin for functional tricuspid regurgitation in patients with heart failure with preserved ejection fracti…
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CLINICAL_TRIALS trial_result · 2025-12-23Clinical Trial Update: Leveraging Exercise Stress Echocardiography for Heart Failure With Preserved Ejection Fraction [NA]
This clinical trial update reports the completion of a study evaluating exercise stress echocardiography in patients with heart failure with…
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CLINICAL_TRIALS trial_result · 2025-12-15Clinical Trial Update: Study to Evaluate Sex Differences in the Acute Effects of PL-3994 in Heart Failure Subjects [Phase 2]
The Phase 2 study evaluating sex differences in the acute effects of PL-3994 in heart failure with preserved ejection fraction has been term…
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CLINICAL_TRIALS trial_result · 2025-12-03Clinical Trial Update: Empagliflozin on Patients With Preserved Heart Failure [NA]
A clinical trial evaluating empagliflozin in patients with heart failure with preserved ejection fraction has completed.
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CLINICAL_TRIALS trial_result · 2025-11-26Clinical Trial Update: Research Study to Look at How Well Semaglutide Works in People Living With Heart Failure, Obesity and Type 2 Diabetes [Phase 3]
Phase 3 trial update indicates the completion of a study evaluating semaglutide for heart failure with preserved ejection fraction and type …
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CLINICAL_TRIALS trial_result · 2025-11-17Clinical Trial Update: Safety & Effectiveness of Tovinontrine in Chronic Heart Failure With Preserved Ejection Fraction (Cycle-2-PEF) [Phase 2]
The Phase 2 trial Cycle-2-PEF evaluating Tovinontrine for heart failure with preserved ejection fraction has completed, reporting on safety …
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CLINICAL_TRIALS trial_result · 2025-09-18Clinical Trial Update: Transthyretin Amyloidosis Cardiomyopathy in Patients With HFpEF in Russia
AstraZeneca-sponsored clinical trial evaluating transthyretin amyloidosis cardiomyopathy in patients with heart failure with preserved eject…
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CLINICAL_TRIALS trial_result · 2025-09-04Clinical Trial Update: Sleep Extension to Improve Sleep Efficiency and QoL in HF With Preserved Ejection Fraction: the SLEEP-HF Pilot Study [NA]
A completed pilot clinical trial evaluating whether extending sleep duration improves sleep efficiency and quality of life in patients with …
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CLINICAL_TRIALS trial_result · 2025-09-04Clinical Trial Update: Study of HS135 in Obese Patients With Pulmonary Hypertension and Heart Failure With Preserved Ejection Fraction [Phase 1]
A Phase 1 study of HS135 in obese patients with heart failure with preserved ejection fraction and pulmonary hypertension was terminated.
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CLINICAL_TRIALS trial_result · 2025-08-27Clinical Trial Update: Study to Evaluate the Efficacy and Safety of AZD4831 in Participants With Heart Failure With Left Ventricular Ejection Fraction > 40% [Phase 2, Phase 3]
A Phase 2/3 trial evaluating the efficacy and safety of AZD4831 in heart failure with preserved ejection fraction has completed, and the res…
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CLINICAL_TRIALS trial_result · 2025-08-20Clinical Trial Update: A Study of Tirzepatide (LY3298176) in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF) and Obesity: The SUMMIT Trial [Phase 3]
Phase 3 SUMMIT trial evaluating tirzepatide in obesity and heart failure with preserved ejection fraction has completed; results were posted…
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CLINICAL_TRIALS trial_result · 2025-08-17Clinical Trial Update: Dapagliflozin With or Without Spironolactone for HFpEF [Phase 2, Phase 3]
Phase 2/3 trial update evaluating dapagliflozin with or without spironolactone for heart failure with preserved ejection fraction has comple…
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CLINICAL_TRIALS trial_result · 2025-08-07Clinical Trial Update: Hemodynamic-GUIDEd Management of Heart Failure [NA]
Abbott Medical Devices completed a trial on hemodynamic-guided management of heart failure; results were posted on 2025-08-07.
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CLINICAL_TRIALS trial_result · 2025-07-30Clinical Trial Update: Neuromuscular Fatigue and Exercise Capacity in Patients With Type 2 Diabetes Mellitus and HFpEF
This item reports a completed clinical trial evaluating neuromuscular fatigue and exercise capacity in patients with Type 2 diabetes mellitu…
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CLINICAL_TRIALS trial_result · 2025-07-18Clinical Trial Update: Sotagliflozin in Heart Failure With Preserved Ejection Fraction (HFpEF) Patients [Phase 4]
Phase 4 clinical trial of sotagliflozin in heart failure with preserved ejection fraction has completed.
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CLINICAL_TRIALS trial_result · 2025-07-17Clinical Trial Update: Frailty and Outcomes in Older Heart Failure Patients With Ejection Fraction >40%
An update on an ongoing clinical trial evaluating frailty and outcomes in older heart failure patients with EF >40%, covering heart failure …
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CLINICAL_TRIALS trial_result · 2025-06-29Clinical Trial Update: IMPROVE-DiCE: Study to Evaluate Effect of IMB-1018972 on Cardiac Energetics in T2DM & Obesity (Pt 1) With HFpEF (Pt 2) [Phase 2]
This update reports the completion of a Phase 2 study evaluating IMB-1018972 for improving cardiac energetics in adults with type 2 diabetes…
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CLINICAL_TRIALS trial_result · 2025-06-04Clinical Trial Update: Comparison of the Effect of Two Types of Physical Exercises in Patients With Heart Failure With Preserved Ejection Fraction [NA]
A completed clinical trial comparing two types of physical exercise in patients with heart failure with preserved ejection fraction to evalu…
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CLINICAL_TRIALS trial_result · 2025-05-25Clinical Trial Update: LCZ696 in Advanced LV Hypertrophy and HFpEF [Phase 2]
A Phase 2 trial of LCZ696 (sacubitril/valsartan) in advanced left ventricular hypertrophy and heart failure with preserved ejection fraction…
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CLINICAL_TRIALS trial_result · 2025-05-21Clinical Trial Update: Effects of Iron Therapy in Heart Failure With Preserved Ejection Fraction and Iron Deficiency (PREFER-HF) [Phase 3]
Phase 3 trial PREFER-HF evaluating intravenous iron therapy in patients with heart failure with preserved ejection fraction and iron deficie…
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CLINICAL_TRIALS trial_result · 2025-05-18Clinical Trial Update: Effects of Sauna on Cardiac and Skeletal Muscle Function in Patients With HFpEF (SAUNA-HFpEF) [NA]
This completed trial SAUNA-HFpEF studied the effects of sauna exposure on cardiac and skeletal muscle function in patients with heart failur…
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CLINICAL_TRIALS trial_result · 2025-04-09Clinical Trial Update: Mechanisms of LV Remodeling in Hypertensive Patients Working on a Rotational Expeditionary Basis in the Arctic
This clinical trial update outlines a study sponsored by Tomsk National Research Medical Center of the Russian Academy of Sciences examining…
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CLINICAL_TRIALS trial_result · 2025-04-01Clinical Trial Update: Evaluation of GeranylGeranylAcetone in Heart Failure With Preserved Ejection Fraction [Phase 2]
Phase 2 clinical trial evaluating GeranylGeranylAcetone for heart failure with preserved ejection fraction has completed. Sponsor/locations …