Heart Failure with Preserved Ejection Fraction
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CLINICAL_TRIALS trial_result · 2026-07-22Clinical Trial Update: A Randomised, Controlled Trial of a Low-energy Diet for Improving Functional Status in Heart Failure With PRESERVED Ejection Fraction Preserved Ejection Fraction [Phase 2, Phase 3]
A randomized controlled trial evaluated a low-energy diet to improve functional status in heart failure with preserved ejection fraction (HF…
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CLINICAL_TRIALS trial_result · 2026-07-17Clinical Trial Results: Novel Respiratory Training as Part of Palliative Care for Older Adults With Heart Failure [NA]
Trial results report on novel respiratory training as part of palliative care for older adults with heart failure, focusing on aging and fra…
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CLINICAL_TRIALS trial_result · 2026-06-24Clinical Trial Results: Sotagliflozin in Heart Failure With Preserved Ejection Fraction (HFpEF) Patients [Phase 4]
Phase 4 trial evaluating sotagliflozin in heart failure with preserved ejection fraction has completed with posted results.
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CLINICAL_TRIALS trial_result · 2026-06-10Clinical Trial Results: NMES in HF Patients to Improve Functional Recovery Following Hospitalization [NA]
A completed clinical trial evaluating neuromuscular electrical stimulation (NMES) to aid functional recovery after hospitalization in patien…
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: Quality of Sleep of Patients With Predominant Central Sleep Apnea Syndrome(SAS) Whose EF > 45% Treated by ASV
Completed clinical trial evaluating Adaptive Servo-Ventilation for improving sleep quality in patients with central sleep apnea and heart fa…
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: Administration of the SGLT-2 Inhibitor Dapagliflozin in the Patients With Amyloid Cardiomyopathy [NA]
A completed clinical trial evaluating the SGLT-2 inhibitor dapagliflozin in patients with amyloid cardiomyopathy across heart failure phenot…
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity [Phase 3]
A Phase 3 trial evaluating Maridebart Cafraglutide for heart failure with preserved or mildly reduced ejection fraction in people with obesi…
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: Colchicine in Patients With Heart Failure and Preserved Left Ventricular Ejection Fraction [Phase 1, Phase 2]
A clinical trial evaluating colchicine for heart failure with preserved ejection fraction has completed Phase 1 and Phase 2.
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CLINICAL_TRIALS trial_result · 2026-04-22Clinical Trial Update: Open-Label Rollover Study of Levosimendan in PH-HFpEF Patients [Phase 2]
The document reports the completion of an open-label Phase 2 rollover study evaluating levosimendan in patients with pulmonary hypertension …
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CLINICAL_TRIALS trial_result · 2026-04-15Clinical Trial Update: A Study of Sotatercept for the Treatment of Cpc-PH Due to HFpEF (MK-7962-007/A011-16) [Phase 2]
Phase 2 clinical trial update for sotatercept in combined pre- and post-capillary pulmonary hypertension due to heart failure with preserved…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: CMR T1 Mapping for Diagnosis of Cardiac Amyloidosis
Completed clinical trial evaluating cardiac magnetic resonance T1 mapping for diagnosing cardiac amyloidosis.
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CLINICAL_TRIALS trial_result · 2026-04-09Clinical Trial Update: Intracranial Pressure and a Potential Vicious Circle of Atrial Fibrillation in HFpEF
The completed trial update highlights associations among intracranial pressure, optic nerve sheath diameter, venous congestion, and atrial f…
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: Effectiveness of a Cardiac Rehabilitation Program in Elderly Patients With Heart Failure. [NA]
Trial update reporting completion of a study evaluating the effectiveness of a cardiac rehabilitation program in elderly patients with heart…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Ablation Versus Medical Management of Atrial Fibrillation in HFpEF [NA]
The clinical trial evaluating ablation versus medical management for atrial fibrillation in patients with heart failure with preserved eject…
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CLINICAL_TRIALS trial_result · 2026-03-25Clinical Trial Update: Sodium-Glucose Cotransporter 2 Inhibitor Use in a National Heart Failure Telemonitoring Program
This clinical trial update reports the completion of a national telemonitoring program evaluating the use of SGLT2 inhibitors in heart failu…
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CLINICAL_TRIALS trial_result · 2026-03-20Clinical Trial Update: Coronary Sinus Reducer For The Management Of Symptomatic Heart Failure [NA]
This clinical trial update indicates that enrollment is ongoing by invitation for evaluating the Coronary Sinus Reducer device to manage sym…
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CLINICAL_TRIALS trial_result · 2026-03-12Clinical Trial Update: Comparative Effectiveness of Oral Semaglutide vs Sitagliptin Among Individuals With Heart Failure With Preserved Ejection Fraction (STEP-HFpEF DM ORAL)
A comparative effectiveness trial comparing oral semaglutide to sitagliptin in individuals with Type 2 diabetes mellitus and heart failure w…
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CLINICAL_TRIALS trial_result · 2026-03-11Clinical Trial Update: The ENCHANTMENT HIV Study [Phase 2]
The ENCHANTMENT HIV Study, a Phase 2 trial, has completed (status: COMPLETED) and investigates HIV/AIDS with comorbid heart failure with pre…
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CLINICAL_TRIALS trial_result · 2026-03-06Clinical Trial Update: Cardiac and Metabolic Effects of Semaglutide in Heart Failure With Preserved Ejection Fraction [Phase 2]
Phase 2 clinical trial evaluating the cardiac and metabolic effects of semaglutide in heart failure with preserved ejection fraction (HFpEF)…
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CLINICAL_TRIALS trial_result · 2026-02-06Clinical Trial Update: Role of Cardiopulmonary Exercise Testing in People With Heart Failure With Preserved Ejection Fraction
A completed clinical trial evaluating the role of cardiopulmonary exercise testing in people with heart failure with preserved ejection frac…
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CLINICAL_TRIALS trial_result · 2026-02-05Clinical Trial Update: A Study of LY3540378 in Participants With Worsening Chronic Heart Failure With Preserved Ejection Fraction (HFpEF) [Phase 2]
A Phase 2 study evaluating LY3540378 in participants with worsening heart failure with preserved ejection fraction was terminated, and the r…
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CLINICAL_TRIALS trial_result · 2026-01-30Clinical Trial Update: Emulation of the SUMMIT Heart Failure Trial in Healthcare Claims Data
Brigham and Women’s Hospital reports a completed study that emulates the SUMMIT heart failure trial using healthcare claims data. The resear…
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CLINICAL_TRIALS trial_result · 2026-01-30Clinical Trial Update: BLOCKade of Calcium Channels and Beta Adrenergic Receptors for the Treatment of Hypertension in HFpEF [Phase 4]
Phase 4 clinical trial evaluating blockade of calcium channels and beta-adrenergic receptors for hypertension in patients with heart failure…
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CLINICAL_TRIALS trial_result · 2026-01-30Clinical Trial Update: Comparative Effectiveness of Tirzepatide Versus Semaglutide in Individuals With Heart Failure With Preserved Ejection Fraction
A completed comparative effectiveness trial evaluated tirzepatide versus semaglutide in adults with type 2 diabetes and heart failure with p…
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CLINICAL_TRIALS trial_result · 2026-01-29Clinical Trial Update: External Body Pressure in Heart Failure With Preserved Ejection Fraction [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating external body pressure in heart failure with preserved ejection fraction has completed.