Heart Failure with Preserved Ejection Fraction
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CLINICAL_TRIALS research · 2025-12-22Clinical Trial Update: Imaging Histone Deacetylase in the Heart [NA]
Massachusetts General Hospital is conducting a recruiting clinical trial to image histone deacetylase activity in the heart, exploring its r…
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CLINICAL_TRIALS research · 2025-12-19Clinical Trial Update: Sacubitril-Valsartan in Heart Failure With Preserved Ejection Fraction and Secondary Mitral Valve Regurgitation [Phase 4]
Phase 4 trial update for sacubitril/valsartan in heart failure with preserved ejection fraction and functional mitral regurgitation. The stu…
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: The Prevalence of Iron Deficiency and the Effectiveness of Ferinject® in Patients With HFpEF (ID-HFpEF) [Phase 4]
Phase 4 trial evaluating the prevalence of iron deficiency and the effectiveness of Ferinject in patients with heart failure with preserved …
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: Study to Evaluate Safety, Tolerability and Drug Levels of BMS-986435/MYK-224 in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF) [Phase 2]
Phase 2 study evaluating safety, tolerability, and drug levels of BMS-986435/MYK-224 in participants with heart failure with preserved eject…
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CLINICAL_TRIALS research · 2025-12-12Clinical Trial Update: SHort Of Pace - Heart Failure (SHOP-HF) [NA]
A clinical trial named SHOP-HF (Short Of Pace) studying heart failure with preserved ejection fraction is currently recruiting. The sponsor …
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CLINICAL_TRIALS research · 2025-12-12Clinical Trial Update: Comparative Effectiveness of Tirzepatide vs Semaglutide in Participants With Type 2 Diabetes and Heart Failure With Preserved Ejection Fraction
This clinical trial compares tirzepatide to semaglutide in people with type 2 diabetes mellitus and heart failure with preserved ejection fr…
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: Biomechanical Precision Medicine Registry for Patients With and Without Heart Failure
Clinical trial registry update for a Biomechanical Precision Medicine Registry in patients with and without heart failure; the study is curr…
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: A Phase II Clinical Trial of HRS-1893 in the Treatment of Heart Failure With Preserved Ejection Fraction [Phase 2]
Phase II clinical trial evaluating HRS-1893 for heart failure with preserved ejection fraction, currently not yet recruiting.
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: CASTLE-HFpEF (Catheter Ablation for Atrial Fibrillation Patients With Heart Failure With Mildly Reduced and Preserved Ejection Fraction) [NA]
Clinical trial status update for CASTLE-HFpEF evaluating catheter ablation in patients with atrial fibrillation and heart failure with prese…
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CLINICAL_TRIALS research · 2025-11-26Clinical Trial Update: Effects of a Multicomponent Training Program on Cardiac Function, Skeletal Muscle Metabolism, Functional Capacity, and Quality of Life in Patients With HFpEF: SENSORFIT-4HEART Study [NA]
An ongoing clinical trial (SENSORFIT-4HEART) is evaluating the effects of a multicomponent training program on cardiac function and related …
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: HRS9531 Injection in Obese Subjects With Heart Failure With Preserved Ejection Fraction [Phase 2]
Phase 2 clinical trial evaluating HRS9531 injections in obese adults with heart failure with preserved ejection fraction; the study is curre…
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CLINICAL_TRIALS research · 2025-11-19Clinical Trial Update: Diagnosing Heart Failure With Preserved Ejection Fraction in Patients With Unexplained Dyspnea (Diagnose-HFpEF)
A clinical trial update about diagnosing heart failure with preserved ejection fraction in patients with unexplained dyspnea.
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CLINICAL_TRIALS research · 2025-11-19Clinical Trial Update: Cardiovascular and Renal Endpoints With Flozins - an Observational Prospective Study in CKD HFpEF Patients
An observational prospective study investigating cardiovascular and renal outcomes of SGLT2 inhibitors (flozins) in CKD patients with heart …
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: Leg Heat Therapy in Heart Failure With Preserved Ejection Fraction [NA]
The update indicates a clinical trial examining leg heat therapy for heart failure with preserved ejection fraction is currently recruiting.
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CLINICAL_TRIALS research · 2025-10-31Clinical Trial Update: Tailored Exercise Training Study Among Adults With HFpEF [Phase 2, Phase 3]
A tailored exercise training study for adults with heart failure with preserved ejection fraction (HFpEF) is in Phase 2/Phase 3 and currentl…
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CLINICAL_TRIALS research · 2025-10-23Clinical Trial Update: A Preliminary Study for INFORMED [Phase 4]
Phase 4 clinical trial update for INFORMED, an ongoing study led by Weill Medical College of Cornell University, currently enrolling by invi…
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CLINICAL_TRIALS research · 2025-10-23Clinical Trial Update: Circulating RNAs in Acute Congestive Heart Failure
Massachusetts General Hospital is conducting a study on circulating RNAs as potential biomarkers in patients with acute decompensated heart …
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CLINICAL_TRIALS research · 2025-10-20Clinical Trial Update: Inspiratory Muscle Training in HFpEF [NA]
A Mayo Clinic-sponsored clinical trial is evaluating inspiratory muscle training for heart failure with preserved ejection fraction and is c…
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CLINICAL_TRIALS research · 2025-10-20Clinical Trial Update: US Benchmarking Clinical Study
Sponsor eMyosound SAS reports that the US benchmarking clinical study is currently recruiting participants for conditions including heart fa…
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CLINICAL_TRIALS research · 2025-10-09Clinical Trial Update: Enhancing the Natriuretic Peptide System in HFpEF [Phase 1, Phase 2]
This is a Phase 1/Phase 2 clinical trial updating on strategies to enhance the natriuretic peptide system in heart failure with preserved ej…
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CLINICAL_TRIALS research · 2025-10-07Clinical Trial Update: A Randomised, Controlled Trial of a Low-energy Diet for Improving Functional Status in Heart Failure With PRESERVED Ejection Fraction Preserved Ejection Fraction [Phase 2, Phase 3]
An ongoing randomized controlled trial is evaluating a low-energy diet to improve functional status in heart failure with preserved ejection…
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CLINICAL_TRIALS research · 2025-10-02Clinical Trial Update: CAMEO-FONTAN -Dapagliflozin in the Failing Fontan Circulation [Phase 2]
Phase 2 trial of dapagliflozin in patients with failing Fontan circulation is currently recruiting. The study also considers effects in sing…
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CLINICAL_TRIALS research · 2025-10-01Clinical Trial Update: Characteristics, Phenotypes, and TRAITS of Heart Failure With Preserved Ejection Fraction (TRAITS-HFpEF)
This entry describes a recruiting clinical study evaluating characteristics, phenotypes, and traits of heart failure with preserved ejection…
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CLINICAL_TRIALS research · 2025-09-30Clinical Trial Update: Development of Specific Diagnostic Tools for Cardiac Insufficiency With Preserved Ejection Fraction
A completed clinical trial assessing the development of diagnostic tools for heart failure with preserved ejection fraction (HFpEF).
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CLINICAL_TRIALS research · 2025-09-29Clinical Trial Update: Beta-blocker Discontinuation in Heart Failure With Preserved Ejection Fraction [NA]
A recruiting trial evaluating discontinuation of beta-blockers in patients with heart failure and preserved ejection fraction.