Heart Failure with Preserved Ejection Fraction
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: BOOST: Blended Onsite and Offsite Structured Exercise Training and Coaching [NA]
This update covers a clinical trial (BOOST) evaluating a blended onsite and offsite structured exercise training and coaching program for he…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: The Effect of Adiposity on Muscle and Microvascular Function in HFpEF
A UT Southwestern Medical Center study is investigating how adiposity influences muscle and microvascular function in patients with heart fa…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Precision Rehabilitation for Veterans With (HFpEF)
This update describes a recruiting clinical trial studying precision rehabilitation for veterans with heart failure with preserved ejection …
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: CAPTURE-HFpEF: National Study of Identification and Phenotyping of Heart Failure With Preserved Ejection Fraction
This is a protocol for the CAPTURE-HFpEF national study to identify and phenotype heart failure with preserved ejection fraction. Recruitmen…
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: Purinergic Signaling and the Postmenopausal Heart
A clinical trial evaluating purinergic signaling in postmenopausal heart function is currently recruiting. The study targets heart failure w…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Cardiac Rehab Effects in HFpEF [NA]
Clinical trial update on the effects of cardiac rehabilitation in patients with heart failure with preserved ejection fraction, noting the s…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: RESPONDER-HF Trial [NA]
The RESPONDER-HF trial by Corvia Medical is currently ACTIVE_NOT_RECRUITING, evaluating an interatrial shunt device for heart failure (inclu…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: The Use of Advanced Imaging in HFpEF
This clinical trial registry entry indicates that a study evaluating advanced imaging in heart failure with preserved ejection fraction is c…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: Endovascular Ablation of the Right Greater Splanchnic Nerve in Subjects Having HFpEF [NA]
This clinical trial update indicates ongoing recruitment for a study evaluating endovascular ablation of the right greater splanchnic nerve …
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: A Randomized Placebo-procedure Controlled Trial of the Enhancor System (PULmonary Artery Denervation) to Evaluate Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart Disease [NA]
Clinical trial update for a randomized study evaluating the Enhancor System, a pulmonary artery denervation device, in patients with combine…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy [Phase 2]
A Phase 2 clinical trial sponsored by Novo Nordisk is evaluating different doses of CDR132L versus placebo for heart failure with preserved …
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: AI-Based Monitoring System for Chronic Heart Failure With Advanced Wearable and Mini-Invasive Devices
A clinical trial is evaluating an AI-based monitoring system for chronic heart failure using wearable and mini-invasive devices. The study i…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: Prospective Evaluation of AI-ECG for SHD Detection
Imperial College London is conducting a prospective study to evaluate an AI-enabled ECG for detecting structural heart disease; the trial is…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: Exercise Intolerance in Heart Failure
A clinical trial from Johns Hopkins is evaluating exercise intolerance in heart failure with preserved ejection fraction (HFpEF) and is curr…
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: Acute Effect of Nurse-assessed Remote Ischemic Preconditioning on Improving Vascular Parameters in Patients With Suspected Heart Failure With Preserved Ejection Fraction [NA]
Clinical trial update on a study evaluating whether nurse-assessed remote ischemic preconditioning improves vascular parameters in patients …
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Real-Time Monitoring of Heart Failure Across the Yale New Haven Health System
A real-time heart failure monitoring clinical trial across Yale New Haven Health System is currently recruiting participants, focusing on he…
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Investigation on the Impact of Finerenone on Myocardial Remodeling in Patients With Diabetic Kidney Disease and Heart Failure [Phase 4]
Phase 4 clinical trial investigating the effect of finerenone on myocardial remodeling in patients with diabetic kidney disease and heart fa…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: A Study Of CS Reducer For Symptomatic Heart Failure With HFpEF And CMD
This update notes that the CS Reducer trial for symptomatic heart failure with preserved ejection fraction and coronary microvascular dysfun…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Deprescribing Beta-Blockers in Elders With Heart Failure With Preserved Ejection Fraction (DEPRESCRIBE-HFpEF) [Phase 4]
A Phase 4 clinical trial evaluating deprescribing beta-blockers in elderly patients with heart failure with preserved ejection fraction (HFp…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Efficacy of LoDoCo in Improving Exercise Capacity Among Patients With HFpEF and Inflammation [Phase 2]
Phase 2 trial evaluating whether LoDoCo improves exercise capacity in patients with heart failure with preserved ejection fraction and infla…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Testing the CHAT Program for Patients With Heart Failure [NA]
This clinical trial update indicates that the CHAT Program for patients with heart failure with preserved ejection fraction is currently enr…
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: Neprilysin Inhibition to Reduce Myocardial Fibrosis in Heart Failure With Preserved Ejection Fraction [Phase 4]
Phase 4 clinical trial update evaluating a neprilysin inhibitor to reduce myocardial fibrosis in heart failure with preserved ejection fract…
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: Data-Driven Phenotyping in Heart Failure With Preserved Ejection Fraction
A clinical trial update on data-driven phenotyping in heart failure with preserved ejection fraction (HFpEF); the study is currently not yet…
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Impact of Intravenous Iron Repletion On Mechanisms of Exercise InTolerance in HFpEF (IRONMET-HFpEF) [Phase 4]
A Phase 4 clinical trial evaluating intravenous iron repletion to improve exercise tolerance mechanisms in patients with iron deficiency and…
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: EXercise and Activin Inhibition to Modulate InflammatioN Effects on Heart Failure and Cognition (EXAMINE-HFC) [Phase 2]
A Phase 2 trial evaluating exercise plus activin inhibition to modulate inflammation effects in heart failure with preserved ejection fracti…