Giant Cell Tumor of Bone
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Sign up freeTop drugs studied for this disease
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EMA approval · 2025-07-10EMA Authorised: Xbryk (denosumab) — Samsung Bioepis NL B.V.
The European Medicines Agency authorized Xbryk, a denosumab product from Samsung Bioepis NL B.V., for use in giant cell tumor of bone within…
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FDA approval · 2025-02-28FDA Approved: STOBOCLO — Original Application (CELLTRION USA, Inc.)
FDA approved STOBOCLO (denosumab-BMWO) from Celltrion USA under an original Biologics License Application for multiple osteoporosis and canc…
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CLINICAL_TRIALS research · 2024-10-18Clinical Trial Update: Efficacy of ICG-based NIR Imaging in Intralesional Curettage of Giant Cell Tumors of Bone in Limbs: a Prospective, Single-center, Single-arm, Open Study [Phase 1, Phase 2]
This clinical trial update describes a prospective, single-center study evaluating indocyanine green (ICG)–based near-infrared imaging to gu…
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CLINICAL_TRIALS trial_result · 2024-05-20Clinical Trial Update: Long-term Safety Follow-up of Subjects With Giant Cell Tumor of Bone Treated With Denosumab in Study 20062004 [Phase 4]
Phase 4 update reporting long-term safety follow-up data for subjects with giant cell tumor of bone treated with denosumab (Study 20062004);…
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CLINICAL_TRIALS trial_result · 2023-04-19Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Narlumosbart (JMT103) in Patients With Giant Cell Tumor of Bone [Phase 3]
Phase 3 clinical trial evaluating efficacy and safety of Narlumosbart (JMT103) in patients with giant cell tumor of bone.
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CLINICAL_TRIALS trial_result · 2022-10-14Clinical Trial Update: Efficacy and Safety of JMT103 in Patients With Giant Cell Tumor of Bone [Phase 1, Phase 2]
Phase 1/2 clinical trial updating efficacy and safety of JMT103 in giant cell tumor of bone.
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CLINICAL_TRIALS trial_result · 2018-12-10Clinical Trial Update: Study of Denosumab in Subjects With Giant Cell Tumor of Bone [Phase 2]
Phase 2 trial of denosumab in giant cell tumor of bone has completed; results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-11-23Clinical Trial Update: Trial of Dasatinib in Advanced Sarcomas [Phase 2]
Phase 2 trial update for dasatinib in advanced sarcomas, with completed status and results posted in 2018.
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CLINICAL_TRIALS trial_result · 2017-11-30Clinical Trial Update: Safety and Efficacy of Post-operative Denosumab Strategy for Giant Cell Tumor of Bone Treatment in China
A clinical trial update examining the safety and efficacy of using postoperative denosumab for Giant Cell Tumor of Bone in China.
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CLINICAL_TRIALS trial_result · 2017-08-24Clinical Trial Update: Characteristics and Mechanism of Denosumab-treated Giant Cell Tumor of Bone [Phase 3]
Phase 3 clinical trial update detailing the characteristics and mechanism of denosumab in giant cell tumor of bone.
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CLINICAL_TRIALS trial_result · 2016-12-22Clinical Trial Update: Giant Cell Tumor of the Extremities Treated With Surgery and/or Medical Treatment
The clinical trial investigating treatment of Giant Cell Tumor of Bone in the extremities using surgery with or without medical therapy has …
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CLINICAL_TRIALS trial_result · 2016-01-26Clinical Trial Update: Adjuvant Zoledronic Acid in High Risk Giant Cell Tumour of Bone (GCT) [Phase 2]
A Phase 2 trial evaluating adjuvant zoledronic acid in high-risk Giant Cell Tumor of Bone has been terminated.
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CLINICAL_TRIALS trial_result · 2014-03-05Clinical Trial Update: Safety and Efficacy Study of Denosumab in Patients With Recurrent or Unresectable Giant Cell Tumor of Bone [Phase 2]
Phase 2 safety and efficacy study of denosumab in patients with recurrent or unresectable giant cell tumor of bone has completed with result…
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CLINICAL_TRIALS research · 2013-08-30Clinical Trial Update: Study of the Effect of Zoledronate on Local Recurrence After Surgical Treatment of Giant Cell Tumors of Bone Zométa [Phase 1, Phase 2]
Clinical trial update for a Phase 1/2 study evaluating zoledronate (Zometa) in giant cell tumor of bone, which has been terminated.