Gastric Cancer

• CLINICAL_TRIALS trial_result · 2020-02-05
  Clinical Trial Update: Apatinib Combined With SOX Neoadjuvant Therapy for Locally Advanced Gastric Cancer [Phase 2]

  Phase 2 trial update investigating apatinib combined with SOX as neoadjuvant therapy for locally advanced gastric cancer.

• CLINICAL_TRIALS trial_result · 2020-02-05
  Clinical Trial Update: Clinical Outcomes of Laparoscopic D1 Versus D2 Lymphadenectomy for Elderly Patients With Advanced Gastric Cancer [Phase 2]

  Phase 2 clinical trial update comparing laparoscopic D1 versus D2 lymphadenectomy for elderly patients with advanced gastric cancer.

• CLINICAL_TRIALS trial_result · 2020-01-29
  Clinical Trial Update: A Randomized, Double Blind Study Evaluating Paclitaxel With and Without RAD001 in Patients With Gastric Carcinoma After Prior Chemotherapy [Phase 3]

  Phase 3 randomized, double-blind trial comparing paclitaxel with and without RAD001 in advanced gastric cancer after prior chemotherapy (com…

• FDA approval · 2020-01-24
  FDA Approved: TRAZIMERA — Supplemental Application (Pfizer Laboratories Div Pfizer Inc)

  FDA approved Pfizer's supplemental Biologics License Application for TRAZIMERA (trastuzumab-qyyP), a biosimilar to trastuzumab.

• CLINICAL_TRIALS trial_result · 2020-01-22
  Clinical Trial Update: Liquid Biopsy in Monitoring the Neoadjuvant Chemotherapy and Operation in Gastric Cancer [Phase 2]

  Phase 2 trial update exploring the use of liquid biopsy to monitor neoadjuvant chemotherapy and surgical outcomes in gastric and gastro-oeso…

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• CLINICAL_TRIALS trial_result · 2020-01-07
  Clinical Trial Update: Trial of 3-weekly Versus 5-weekly Schedule of S-1 Plus Cisplatin in Gastric Cancer: SOS [Phase 3]

  Phase 3 trial comparing 3-weekly versus 5-weekly S-1 plus cisplatin in advanced gastric cancer has completed.

• CLINICAL_TRIALS trial_result · 2020-01-07
  Clinical Trial Update: Phase II Study of Ramucirumab With Chemotherapy in Patients With Metastatic Gastroesophageal Junction and Gastric Cancer [Phase 2]

  Phase II study of ramucirumab in combination with chemotherapy for metastatic gastric/gastroesophageal junction cancer was terminated; resul…

• CLINICAL_TRIALS trial_result · 2020-01-07
  Clinical Trial Update: Trastuzumab in Combination With Capecitabine and Oxaliplatin(XELOX) in Patients With Advanced Gastric Cancer(AGC): Her+XELOX [Phase 2]

  Phase 2 trial evaluating trastuzumab with XELOX in HER2-positive advanced gastric cancer has completed.

• CLINICAL_TRIALS trial_result · 2020-01-07
  Clinical Trial Update: Dovitinib for Gastric Cancer With FGFR2 Amplification: GASDOVI-1 [Phase 2]

  Phase 2 trial update for dovitinib in gastric cancer with FGFR2 amplification (GASDOVI-1) has completed.

• CLINICAL_TRIALS trial_result · 2020-01-07
  Clinical Trial Update: Sorafenib Trial in Advanced and/or Recurrent Gastric Adenocarcinoma: Treatment Evaluation: STARGATE [Phase 2]

  Phase 2 clinical trial investigating sorafenib in advanced and/or recurrent gastric adenocarcinoma (STARGATE) has completed.

• CLINICAL_TRIALS trial_result · 2020-01-07
  Clinical Trial Update: RAD001 in Advanced Gastric Cancer Who Failed Standard First-line Treatment With pS6 Ser 240/4 Expression [Phase 2]

  Phase 2 trial update of RAD001 in advanced gastric cancer after failure of first-line therapy.

• CLINICAL_TRIALS trial_result · 2020-01-07
  Clinical Trial Update: Efficacy of Docetaxel, Capecitabine, Cisplatin, and Bevacizumab in Patients With Unresectable Advanced Gastric Cancer [Phase 2]

  Phase 2 trial updating efficacy of a combination regimen (docetaxel, capecitabine, cisplatin, and bevacizumab) in unresectable advanced gast…

• CLINICAL_TRIALS trial_result · 2020-01-07
  Clinical Trial Update: Study of Vorinostat Plus Capecitabine (X) and Cisplatin (P) for 1st Line Treatment of Metastatic or Recurrent Gastric Cancer: Zolinza+XP [Phase 1, Phase 2]

  Phase 1/2 study evaluating vorinostat plus capecitabine and cisplatin as first-line therapy for metastatic or recurrent gastric cancer has c…

• CLINICAL_TRIALS trial_result · 2020-01-07
  Clinical Trial Update: Biweekly FOLFIRI in Advanced Gastric Cancer (AGC) With Failure of Prior Taxane, Fluoropyrimidine, and Cisplatin [Phase 2]

  Phase 2 trial of biweekly FOLFIRI in advanced gastric cancer after failure of taxane, fluoropyrimidine, and cisplatin has completed.

• CLINICAL_TRIALS trial_result · 2020-01-07
  Clinical Trial Update: Adjuvant Chemotherapy With Docetaxel, Capecitabine and Cisplatin in Patients With Advanced Gastric Cancer: Adjuvant DXP [Phase 2]

  Phase 2 trial evaluating adjuvant chemotherapy with docetaxel, capecitabine, and cisplatin (DXP) in patients with resected advanced gastric …

• CLINICAL_TRIALS trial_result · 2019-12-30
  Clinical Trial Update: Study of AZD5363 in Combination With Paclitaxel, in Advanced Gastric Adenocarcinoma Patients Harboring PIK3CA Mutation and/or PIK3CA Amplification as a Second-line Chemotherapy [Phase 2]

  Phase 2 trial evaluating AZD5363 in combination with paclitaxel for advanced gastric adenocarcinoma with PIK3CA mutation or amplification; s…

• CLINICAL_TRIALS withdrawal · 2019-12-30
  Clinical Trial Update: Trial Comparing Capecitabine Plus Oxaliplatin (XELOX) and Capecitabine (X) as First-line Chemotherapy in Elderly Patients With Advanced Gastric Cancer [Phase 3]

  Phase 3 trial comparing XELOX vs capecitabine alone in elderly patients with advanced gastric cancer was withdrawn.

• CLINICAL_TRIALS trial_result · 2019-12-19
  Clinical Trial Update: Study to Explore the Safety, Tolerability and Efficacy of MK-3475 in Combination With INCB024360 in Participants With Selected Cancers [Phase 1, Phase 2]

  Phase 1/2 trial evaluating MK-3475 (pembrolizumab) in combination with INCB024360 in various selected cancers; study completed with results …

• CLINICAL_TRIALS trial_result · 2019-12-17
  Clinical Trial Update: Tripletrumab Combined With Oxaliplatin and Teggio (SOX) in First-line Treatment of Gastric and Gastroesophageal Junction Adenocarcinoma [Phase 2]

  Phase 2 trial evaluating tripletrumab plus SOX as first-line treatment for gastric cancer and gastroesophageal junction adenocarcinoma.

• CLINICAL_TRIALS trial_result · 2019-12-11
  Clinical Trial Update: Autologous CAR-T/TCR-T Cell Immunotherapy for Malignancies [Phase 1, Phase 2]

  Phase 1/2 clinical trial update for autologous CAR-T/TCR-T cell immunotherapy targeting multiple malignancies; current status is unknown.

• CLINICAL_TRIALS trial_result · 2019-12-10
  Clinical Trial Update: Study of Modified Docetaxel, Cisplatin, and Fluorouracil (mDCF) in Unresectable or Metastatic Gastric and Gastroesophageal Junction Adenocarcinoma [Phase 2]

  A Phase 2 trial evaluating a modified DCF regimen (docetaxel, cisplatin, and fluorouracil) in unresectable or metastatic gastric and gastroe…

• CLINICAL_TRIALS trial_result · 2019-12-03
  Clinical Trial Update: Camrelizumab, Apatinib and Nab-paclitaxel as Second-line Treatment in Advanced Gastric Cancer [Phase 1, Phase 2]

  Clinical trial update on camrelizumab, apatinib, and nab-paclitaxel as second-line treatment for advanced gastric cancer in Phase 1/2.

• CLINICAL_TRIALS trial_result · 2019-11-26
  Clinical Trial Update: Clinical Study of Propranolol Combined With Neoadjuvant Chemotherapy in Gastric Cancer [Phase 2]

  Phase 2 clinical trial investigating propranolol in combination with neoadjuvant chemotherapy for gastric cancer.

• CLINICAL_TRIALS trial_result · 2019-11-19
  Clinical Trial Update: Preoperative Intravenous Iron Therapy in Patients With Gastric Cancer [Phase 4]

  Phase 4 clinical trial evaluating preoperative intravenous iron therapy in patients with gastric cancer and anemia.

• CLINICAL_TRIALS trial_result · 2019-11-18
  Clinical Trial Update: Genotype Guided Chemotherapy in Gastric Cancer Patients [Phase 2]

  Phase 2 trial investigating genotype-guided chemotherapy in metastatic gastric cancer has completed.