Gastric Cancer

CLINICAL_TRIALS research · 2026-03-25

Clinical Trial Update: A Clinical Study of Sintilimab Combined With Chemothrapy Versus Chemotherapy as Adjuvant Therapy for Gastric/Gastroesophageal Junction Adenocarcinoma [Phase 2]

A Phase 2 clinical trial in China evaluating sintilimab plus chemotherapy versus chemotherapy alone as adjuvant therapy for gastric or gastr…

CLINICAL_TRIALS research · 2026-03-24

Clinical Trial Update: A Real-World, Single-Arm Study Protocol of Disitamab Vedotin in Combination With Immunotherapy and Multimodal Radiation Therapy for HER2-Positive Advanced Gastric Cancer: After Second-Line Treatment Failure

This document outlines a real-world, single-arm study protocol evaluating disitamab vedotin in combination with immunotherapy and multimodal…

CLINICAL_TRIALS research · 2026-03-23

Clinical Trial Update: A Phase 1/1b of RNDO-564 Single Agent or in Combination With Pembrolizumab in Bladder Cancer and Other Solid Tumors Associated With Nectin-4 [Phase 1]

Phase 1/1b trial evaluating RNDO-564 as a single agent or in combination with pembrolizumab in bladder cancer and nectin-4–associated solid …

CLINICAL_TRIALS research · 2026-03-23

Clinical Trial Update: Nivolumab +/- Relatlimab Prior to Chemoradiation With II/III Gastro/Esophageal Cancer [Phase 1]

Phase 1 clinical trial evaluating nivolumab with or without relatlimab before chemoradiation in patients with gastric or esophageal cancers;…

CLINICAL_TRIALS research · 2026-03-23

Clinical Trial Update: Testing the Addition of Radiotherapy to the Usual Treatment (Chemotherapy) for Patients With Esophageal and Gastric Cancer That Has Spread to a Limited Number of Other Places in the Body [Phase 3]

A Phase 3 trial is evaluating whether adding radiotherapy to standard chemotherapy improves outcomes for patients with metastatic esophageal…

CLINICAL_TRIALS research · 2026-03-23

Clinical Trial Update: Esomeprazole Plus Sucralfate for Post-ESD Ulcer Healing [Phase 4]

Phase 4 clinical trial evaluating esomeprazole plus sucralfate for healing ulcers after endoscopic submucosal dissection in gastric neoplasm…

CLINICAL_TRIALS research · 2026-03-23

Clinical Trial Update: Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid Tumors [Phase 1]

Open-label Phase 1 study evaluating BL-M07D1 in HER2-expressing malignant solid tumors, with recruitment across several tumor types includin…

CLINICAL_TRIALS research · 2026-03-20

Clinical Trial Update: A Phase 1 First-In-Human Study of the Anti-CD73 IPH5301 Alone or in Combination With Chemotherapy and Trastuzumab in Patients With Advanced Solid Tumors [Phase 1]

A Phase 1 first-in-human study of IPH5301, an anti-CD73 antibody, given alone or with chemotherapy and trastuzumab, in patients with advance…

CLINICAL_TRIALS research · 2026-03-20

Clinical Trial Update: A Multicentre Prospective Cohort Study of The Gastric Precancerous Epithelial Pathway Using High-Definition Endoscopy And Histopathology In India

A multicenter prospective cohort study in India evaluating the gastric precancerous epithelial pathway using high-definition endoscopy and h…

CLINICAL_TRIALS research · 2026-03-20

Clinical Trial Update: Fluorescence Guided Laparoscopic-Endoscopic Cooperative Sentinel Lymph Node Navigation Surgery Strategy for Early Gastric Cancer [NA]

This clinical trial update describes a fluorescence-guided sentinel lymph node navigation strategy using laparoscopic-endoscopic cooperation…

CLINICAL_TRIALS research · 2026-03-20

Clinical Trial Update: Evaluation of Pressurized Intraperitoneal Aerosol Chemotherapy With VRT106 Versus PIPAC in Patients With Advanced Gastric Cancer and PeritonealMetastasis: A Prospective, Multicenter, Open-Label, Randomized Controlled Trial [Phase 2]

A Phase 2 randomized controlled trial compares VRT106-based pressurized intraperitoneal aerosol chemotherapy with standard PIPAC in advanced…

CLINICAL_TRIALS trial_result · 2026-03-19

Clinical Trial Update: Treatment of Cabotamig (ARB202) in Advanced Gastrointestinal Cancer Patients [Phase 1]

Phase 1 trial of Cabotamig (ARB202) in advanced gastrointestinal cancers has completed; no specific efficacy results are provided in the doc…

CLINICAL_TRIALS trial_result · 2026-03-19

Clinical Trial Update: Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12D Variant of Mutated RAS in HLA-A*11:01 Patients [Phase 1, Phase 2]

This update reports on a Phase 1/2 trial of peripheral blood lymphocytes transduced with a murine T-cell receptor recognizing the G12D varia…

CLINICAL_TRIALS research · 2026-03-19

Clinical Trial Update: Phase II Trial of Neoadjuvant Thymalfasin, PD-1 Inhibitor, and Chemoradiotherapy for cStage III GEJ Adenocarcinoma [Phase 2]

This Clinical Trials update notes a Phase II neoadjuvant trial combining thymosin alpha-1, a PD-1 inhibitor, and chemoradiotherapy for stage…

CLINICAL_TRIALS research · 2026-03-19

Clinical Trial Update: Study of Dato-DXd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03) [Phase 2]

AstraZeneca's Dato-DXd is being studied as a single agent and in combination with other anti-cancer drugs in an ongoing Phase 2 trial for ad…

CLINICAL_TRIALS research · 2026-03-19

Clinical Trial Update: IBI343 in Combination Therapy for Advanced Malignant Solid Tumors [Phase 2]

This is a Phase 2 clinical trial update for IBI343 in combination therapy targeting CLDN18.2-positive advanced solid tumors, including gastr…

CLINICAL_TRIALS other · 2026-03-19

Clinical Trial Update: IBI343 in Combination With Sintilimab and SOX Regimen for Perioperative Treatment of Resectable, Locally Advanced Gastric or Gastroesophageal Junction Adenocarcinoma [Phase 2]

Phase 2 trial update for IBI343 in combination with sintilimab and the SOX regimen for perioperative treatment of resectable, locally advanc…