Gastric Cancer

• CLINICAL_TRIALS trial_result · 2025-03-17
  Clinical Trial Update: Pembrolizumab/Placebo Plus Trastuzumab Plus Chemotherapy in Human Epidermal Growth Factor Receptor 2 Positive (HER2+) Advanced Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma (MK-3475-811/KEYNOTE-811) [Phase 3]

  Phase 3 trial MK-3475-811/KEYNOTE-811 evaluating pembrolizumab plus placebo with trastuzumab and chemotherapy in HER2-positive advanced gast…

• CLINICAL_TRIALS trial_result · 2025-03-13
  Clinical Trial Update: Study Maintenance Regorafenib vs Placebo, no Progression Patients After I Line Chemotherapy Metastatic Gastric Cancer [Phase 2]

  Phase 2 randomized study comparing regorafenib maintenance to placebo in metastatic gastric cancer patients who did not progress after first…

• CLINICAL_TRIALS trial_result · 2025-03-12
  Clinical Trial Update: Conversion Effects of PD-1 Antibody Camrelizumab Combined With Nab-POF Regimen Chemotherpy in Patients With Initially Unresectable Locally Advanced or Limited Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma：FDZL-GC001 Trial [Phase 2]

  Phase 2 trial (NCT04510064) evaluated camrelizumab combined with nab-POF chemotherapy in patients with initially unresectable locally advanc…

• CLINICAL_TRIALS trial_result · 2025-03-11
  Clinical Trial Update: Blood Tests for Gastritis and Gastric Neoplasms

  A completed clinical trial examining blood-based tests for detecting gastritis and gastric neoplasms has posted results.

• CLINICAL_TRIALS trial_result · 2025-03-11
  Clinical Trial Update: The Effect of Post-operative Exercise in Gastric Cancer Patients: A Randomized Controlled Trial (RCT) Study [NA]

  This randomized controlled trial investigates post-operative exercise in gastric cancer patients. The study has completed, but results are n…

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• CLINICAL_TRIALS trial_result · 2025-03-11
  Clinical Trial Update: Expanded Indications of Endoscopic Submucosal Dissection for Early Gastric Cancer in China

  A completed clinical trial reports expanded indications for endoscopic submucosal dissection to treat early gastric cancer in China.

• CLINICAL_TRIALS trial_result · 2025-03-04
  Clinical Trial Update: Safety of 250ml Preoperative Carbohydrate Drink in Gastric Cancer Patients [NA]

  Completed clinical trial assessing the safety of a 250 ml preoperative carbohydrate drink in gastric cancer patients.

• CLINICAL_TRIALS trial_result · 2025-02-28
  Clinical Trial Update: Prospective Evaluation and Molecular Profiling in People With Gastric Tumors

  This clinical trial update describes a prospective evaluation and molecular profiling of gastric tumors (gastric cancer), with the study sta…

• CLINICAL_TRIALS trial_result · 2025-02-26
  Clinical Trial Update: Safety Study of MGAH22 in HER2-positive Carcinomas [Phase 1]

  This clinical trial update reports a Phase 1 safety study of MGAH22 in HER2-positive carcinomas, which has completed.

• CLINICAL_TRIALS trial_result · 2025-02-20
  Clinical Trial Update: Study of Pembrolizumab (MK-3475) Plus Chemotherapy Versus Placebo Plus Chemotherapy in Participants With Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma (MK-3475-585/KEYNOTE-585)-China Extension [Phase 3]

  This is the China extension of the Phase 3 KEYNOTE-585 trial evaluating pembrolizumab plus chemotherapy versus placebo plus chemotherapy in …

• CLINICAL_TRIALS trial_result · 2025-02-20
  Clinical Trial Update: Study of Pembrolizumab (MK-3475) Plus Chemotherapy Versus Placebo Plus Chemotherapy in Participants With Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma (MK-3475-585/KEYNOTE-585) [Phase 3]

  A Phase 3 trial (MK-3475-585/KEYNOTE-585) evaluating pembrolizumab plus chemotherapy versus chemotherapy alone in gastric cancer and gastroe…

• CLINICAL_TRIALS trial_result · 2025-02-20
  Clinical Trial Update: Chemotherapy and Pembrolizumab, Followed by Pembrolizumab and Olaparib As Firstline Therapy in Her-2 Negative Gastric/GEJ Adenocarcinoma [Phase 2]

  This Phase 2 trial update indicates completion of a first-line therapy approach for HER2-negative gastric/GEJ adenocarcinoma using chemother…

• CLINICAL_TRIALS trial_result · 2025-02-20
  Clinical Trial Update: Heated Intra-peritoneal Chemotherapy With Doxorubicin and Cisplatin for Abdominal for Pelvic Tumors in Pediatric Patients [EARLY_Phase 1]

  Early-phase 1 clinical trial evaluating heated intraperitoneal chemotherapy with doxorubicin and cisplatin for pediatric abdominal/pelvic tu…

• CLINICAL_TRIALS trial_result · 2025-02-20
  Clinical Trial Update: Plasma Metabolic Biomarkers for Gastric Cancer Diagnosis

  This update reports the completion of a clinical trial evaluating plasma metabolic biomarkers for diagnosing gastric cancer.

• CLINICAL_TRIALS trial_result · 2025-02-19
  Clinical Trial Update: Heated Intraperitoneal Chemotherapy and Gastrectomy for Gastric Cancer With Positive Peritoneal Cytology [Phase 2]

  This document reports the completion of a Phase 2 trial evaluating heated intraperitoneal chemotherapy plus gastrectomy for gastric cancer w…

• CLINICAL_TRIALS trial_result · 2025-02-14
  Clinical Trial Update: Tislelizumab in Combination With Chemotherapy as First-Line Treatment in Adults With Inoperable, Locally Advanced or Metastatic Gastric, or Gastroesophageal Junction Carcinoma [Phase 3]

  Phase 3 trial evaluated tislelizumab in combination with chemotherapy as first-line treatment for adults with inoperable, locally advanced o…

• CLINICAL_TRIALS trial_result · 2025-02-12
  Clinical Trial Update: Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy, Phase 1 Study of CMG901 [Phase 1]

  This Phase 1 study of CMG901 in patients with advanced solid tumors, including gastric cancer and pancreatic cancer, assesses safety, tolera…

• CLINICAL_TRIALS trial_result · 2025-02-07
  Clinical Trial Update: A Study of SGN-STNV in Advanced Solid Tumors [Phase 1]

  Seagen's Phase 1 study of SGN-STNV in advanced solid tumors has been terminated.

• CLINICAL_TRIALS trial_result · 2025-02-07
  Clinical Trial Update: Laparoscopic Staging for Locally Advanced Gastric Cancer in Chinese Patients [NA]

  A completed clinical trial conducted in Chinese patients evaluating laparoscopic staging for locally advanced gastric cancer; no efficacy or…

• CLINICAL_TRIALS trial_result · 2025-02-06
  Clinical Trial Update: Impact of Robotic Surgery on Systemic Immune-inflammation Index

  A completed clinical trial evaluating whether robotic surgery influences the systemic immune-inflammation index in gastric cancer.

• CLINICAL_TRIALS trial_result · 2025-01-29
  Clinical Trial Update: Establishment of Molecular Classification Models for Early Diagnosis of Digestive System Cancers

  This completed trial developed molecular classification models for early diagnosis of digestive system cancers and assessed their ability to…

• CLINICAL_TRIALS trial_result · 2025-01-24
  Clinical Trial Update: POWER AUDIT, Postoperative Outcomes Within an Enhanced Recovery After Surgery Protocol After Gastric Surgery (POWER 4 + 3)

  A clinical trial update for POWER AUDIT evaluating postoperative outcomes within an Enhanced Recovery After Surgery protocol after gastric s…

• CLINICAL_TRIALS trial_result · 2025-01-23
  Clinical Trial Update: Validation Study on the Removal of EpCAM-positive Tumour Cells From Blood Collected During Tumour Surgery Using Catumaxomab/Catuvab Device [NA]

  A completed validation trial evaluated removal of EpCAM-positive tumor cells from blood collected during tumor surgery using the Catumaxomab…

• CLINICAL_TRIALS trial_result · 2025-01-17
  Clinical Trial Update: Phase II Randomized Trial of Bethesda Protocol Compared to Cambridge Method for Detection of Early Stage Gastric Cancer in CDH1 Mutation Carriers [Phase 2]

  Phase II randomized trial comparing the Bethesda Protocol to the Cambridge Method for detection of early-stage gastric cancer in CDH1 mutati…

• CLINICAL_TRIALS trial_result · 2025-01-15
  Clinical Trial Update: PD1 Combined With Chemotherapy for Adjuvant Treatment of Gastric Cancer [Phase 3]

  Phase 3 trial update on PD-1 inhibitor in combination with chemotherapy as adjuvant treatment for gastric cancer, with the study currently a…