Gastric Cancer

CLINICAL_TRIALS research · 2025-07-31

Clinical Trial Update: Novel SEQUEnced Immunotherapy With Anti-angiogenesis and Chemotherapy in Advanced gastroesophageaL Adenocarcinoma [Phase 2]

A Phase 2 clinical trial update for sequential immunotherapy combining anti-angiogenesis and chemotherapy in advanced gastroesophageal junct…

CLINICAL_TRIALS research · 2025-07-31

Clinical Trial Update: Screening and Validation of Serum Protein Biomarkers for Early Diagnosis of Gastric Cancer

This clinical trial update describes the screening and validation of serum protein biomarkers for the early diagnosis of gastric cancer. The…

CLINICAL_TRIALS research · 2025-07-31

Clinical Trial Update: Irinotecan Liposome II + 5-FU/LV + Oxaliplatin + Karelizumab in Neoadjuvant Treatment of Gastric Cancer [Phase 2]

Phase 2 neoadjuvant trial evaluating irinotecan liposome II combined with 5-FU/leucovorin, oxaliplatin, and Karelizumab for gastric cancer; …

CLINICAL_TRIALS research · 2025-07-29

Clinical Trial Update: Efficacy and Safety of AK112 Combined Chemotherapy as Neoadjuvant Treatment for Signet Ring Cell-containing G/GEJ Adenocarcinoma [Phase 2]

A Phase 2 trial is evaluating AK112 in combination with chemotherapy as neoadjuvant therapy for signet ring cell-containing gastric or gastr…

CLINICAL_TRIALS research · 2025-07-29

Clinical Trial Update: Pucotenlimab Combined With Chemotherapy as Perioperative Treatment for Locally Advanced Gastroesophageal Junction Carcinoma [NA]

Clinical trial update shows pucotenlimab with chemotherapy is being studied as perioperative therapy for locally advanced gastroesophageal j…

CLINICAL_TRIALS research · 2025-07-28

Clinical Trial Update: Comparison of the Sensitivity of pCLE and Pathological Biopsy Before ESD

This clinical trial assesses the relative sensitivity of probe-based confocal laser endomicroscopy (pCLE) versus standard pathological biops…

CLINICAL_TRIALS research · 2025-07-25

Clinical Trial Update: Study of Atezolizumab + FLOT vs. FLOT Alone in Patients With GC/GEJ and High Immune Responsiveness [Phase 2]

Phase 2 study evaluating atezolizumab added to the FLOT chemotherapy regimen versus FLOT alone in patients with gastric cancer or gastroesop…

CLINICAL_TRIALS research · 2025-07-23

Clinical Trial Update: The Advantages and Disadvantages of Linear Anastomat and Tubular Anastomat in Radical Gastrectomy of Distal Gastric Cancer [NA]

Clinical trial update comparing linear anastomosis and tubular anastomosis techniques in radical gastrectomy for distal gastric cancer; the …

CLINICAL_TRIALS research · 2025-07-23

Clinical Trial Update: Acupuncture for Oxaliplatin-induced Peripheral Neuropathy in Gastro-intestinal Cancer Patients [NA]

This clinical trial is evaluating acupuncture to address oxaliplatin-induced peripheral neuropathy in patients with gastrointestinal cancers…

CLINICAL_TRIALS research · 2025-07-22

Clinical Trial Update: Application of a New Surgical Technique in Proximal Gastrectomy: a Prospective, Multicenter Randomized Controlled Study [NA]

Prospective, multicenter randomized controlled study evaluating a new surgical technique for proximal gastrectomy in gastric cancer, specifi…

CLINICAL_TRIALS research · 2025-07-22

Clinical Trial Update: Laparoscopic and Endoscopic Collaborative Surgery as Rescue-treatment for Advanced Gastric Cancer [NA]

This clinical trial is recruiting in Region Stockholm to evaluate laparoscopic and endoscopic collaborative surgery as a rescue-treatment fo…

CLINICAL_TRIALS research · 2025-07-22

Clinical Trial Update: Development and Validation of Metabolic Biomarkers for Early Diagnosis, Prognosis, and Recurrence of Gastric Cancer：MetBio-GC

A clinical trial to develop and validate metabolic biomarkers for early diagnosis, prognosis, and recurrence of gastric cancer is currently …

CLINICAL_TRIALS research · 2025-07-22

Clinical Trial Update: A Study of Minimally Invasive Proximal Gastrectomy Versus Minimally Invasive Total Gastrectomy for Gastric and Gastroesophageal Junction Cancers

A clinical trial comparing minimally invasive proximal gastrectomy versus minimally invasive total gastrectomy for gastric and gastroesophag…

CLINICAL_TRIALS research · 2025-07-20

Clinical Trial Update: Tislelizumab Plus FOLFOX Versus POF in the Treatment of Locally Advanced: a Multicenter, Open-label, Randomized Phase III Studyunresectable or Metastatic Gastric/Gastroesophageal Junction Adenocarcinoma [Phase 3]

A multicenter, open-label Phase III study randomizes tislelizumab plus FOLFOX versus POF in locally advanced or metastatic gastric and gastr…

CLINICAL_TRIALS research · 2025-07-17

Clinical Trial Update: The Construction of a Predictive Model for Gastric Cancer Immunotherapy Response Based on Tumor-Infiltrating Lymphocytes (TILs) and Histone H3K4me3 in the Tumor Microenvironment

This clinical trial update describes a study to construct a predictive model for gastric cancer immunotherapy response based on tumor-infilt…

CLINICAL_TRIALS research · 2025-07-17

Clinical Trial Update: Gastrectomy + Cytoreductive Surgery + HIPEC for Gastric Cancer With Peritoneal Dissemination. [Phase 3]

A Phase 3 clinical trial evaluating gastrectomy with cytoreductive surgery and HIPEC for gastric cancer with peritoneal dissemination is cur…

CLINICAL_TRIALS research · 2025-07-16

Clinical Trial Update: Perioperative Tislelizumab Plus Chemotherapy Versus Chemotherapy Alone in MHC-II-Positive Gastric/GEJ Cancer [Phase 3]

A Phase 3 trial is investigating perioperative tislelizumab plus chemotherapy versus chemotherapy alone for MHC-II-positive gastric/GEJ canc…

CLINICAL_TRIALS research · 2025-07-16

Clinical Trial Update: Study of SBRT/Olaparib Followed by Pembrolizumab/Olaparib in Gastric Cancers [Phase 2]

A Phase 2 clinical trial evaluating SBRT/Olaparib followed by Pembrolizumab/Olaparib in gastric and gastroesophageal cancers; currently acti…

CLINICAL_TRIALS research · 2025-07-16

Clinical Trial Update: Clinical Evaluation of GRAPE Model for Gastric Cancer Screening

An ongoing clinical trial assessing the GRAPE model for gastric cancer screening, currently recruiting.

CLINICAL_TRIALS research · 2025-07-16

Clinical Trial Update: Clinical Validation of an MCED Test in Symptomatic Populations (K-ACCELERATE)

This update describes the ongoing clinical validation of a multi-cancer early detection (MCED) test in symptomatic populations, with enrollm…