Gastric Cancer

• CLINICAL_TRIALS research · 2025-12-26
  Clinical Trial Update: Intraperitoneal Paclitaxel and Systemic Therapy Versus Systemic Therapy Alone in Gastric Cancer Patients With Peritoneal Metastasis [Phase 3]

  A Phase 3 randomized trial is evaluating intraperitoneal paclitaxel plus systemic therapy versus systemic therapy alone in gastric cancer wi…

• CLINICAL_TRIALS research · 2025-12-24
  Clinical Trial Update: Assessing Durvalumab and FLOT Chemotherapy in Resectable Gastric and Gastroesophageal Junction Cancer [Phase 3]

  A Phase 3 trial evaluating the combination of durvalumab with the FLOT chemotherapy regimen in resectable gastric and gastroesophageal junct…

• CLINICAL_TRIALS research · 2025-12-24
  Clinical Trial Update: Clinical Application of PET Imaging Targeting CLDN18.2 in Malignant Tumors

  A clinical trial is evaluating PET imaging targeting CLDN18.2 for detecting malignant tumors, with recruitment ongoing in gastric cancer, pa…

• CLINICAL_TRIALS research · 2025-12-23
  Clinical Trial Update: Oral Supplementation of Glutamine on Gastric Cancer Patients After Gastrectomy [NA]

  This clinical trial explores oral glutamine supplementation in gastric cancer patients after gastrectomy and is currently recruiting.

• CLINICAL_TRIALS research · 2025-12-22
  Clinical Trial Update: Phase II RAINSPOT: Zolbetuximab-Paclitaxel-Ramucirumab for CLDN18.2 Positive Gastro-esophageal Cancer [Phase 2]

  Phase II trial (RAINSPOT) evaluating zolbetuximab combined with paclitaxel and ramucirumab in CLDN18.2-positive gastric and gastroesophageal…

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• CLINICAL_TRIALS research · 2025-12-19
  Clinical Trial Update: Novel Humanized Ferritin-Based NIR Fluorescent Probe for Identifying Sentinel Lymph Node Metastasis in Early Gastric Cancer

  This document outlines an ongoing clinical trial evaluating a novel humanized ferritin-based near-infrared fluorescent probe to identify sen…

• CLINICAL_TRIALS research · 2025-12-19
  Clinical Trial Update: Aldesleukin With Nivolumab and Standard Chemotherapy for Treatment of Gastric Cancer With Peritoneal Metastasis [Phase 1]

  This is a Phase 1 clinical trial evaluating Aldesleukin in combination with Nivolumab and standard chemotherapy for clinical stage IV gastri…

• CLINICAL_TRIALS research · 2025-12-19
  Clinical Trial Update: Sentinel Node Resection With or Without LECS After Noncurative ESD for EGC [NA]

  This clinical trial will compare sentinel node resection with or without LECS after noncurative endoscopic submucosal dissection in patients…

• CLINICAL_TRIALS research · 2025-12-18
  Clinical Trial Update: Individually Tailored Strategies for the Precision Prevention of Gastric Cancer and Colorectal Cancer in the Community

  A National Taiwan University Hospital-led study describes individually tailored precision prevention strategies for gastric and colorectal c…

• CLINICAL_TRIALS research · 2025-12-18
  Clinical Trial Update: Clinical & Pathological Studies of Upper Gastrointestinal Carcinoma

  Ongoing Stanford University clinical trial evaluating clinical and pathological aspects of upper gastrointestinal cancers, including stomach…

• CLINICAL_TRIALS research · 2025-12-18
  Clinical Trial Update: Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist) [Phase 1, Phase 2]

  This clinical trial update describes a Phase 1/2 study of INBRX-106 in combination with pembrolizumab for locally advanced or metastatic sol…

• CLINICAL_TRIALS research · 2025-12-17
  Clinical Trial Update: Combination of Osemitamab (TST001), Pembrolizumab and Chemotherapy as First-line Therapy in Advanced or Metastatic GC/GEJ Adenocarcinoma [Phase 3]

  This clinical trial update describes a Phase 3 study evaluating a triplet regimen of Osemitamab (TST001), pembrolizumab, and chemotherapy as…

• CLINICAL_TRIALS research · 2025-12-17
  Clinical Trial Update: RCT of Mobile Apps & FitBit v. Usual Care [NA]

  An ongoing randomized trial compares a mobile apps plus FitBit intervention to usual care in patients with pancreatic, gastric, liver, colon…

• CLINICAL_TRIALS research · 2025-12-17
  Clinical Trial Update: Feasibility of Enhanced Recovery After Surgery Without Prophylactic Abdominal Drainage Tubes After Laparoscopic Distal Gastrectomy For Gastric Cancer [Phase 3]

  A Phase 3 trial evaluating the feasibility of enhanced recovery after surgery without prophylactic abdominal drainage tubes in patients unde…

• CLINICAL_TRIALS research · 2025-12-17
  Clinical Trial Update: A Trial to Evaluate Safety and Tolerability of TST001 in Advanced or Metastatic Solid Tumors [Phase 1, Phase 2]

  Clinical trial update for TST001 in advanced or metastatic solid tumors (Phase 1/2); the study is currently active and not recruiting.

• CLINICAL_TRIALS research · 2025-12-17
  Clinical Trial Update: Iparomlimab and Tuvonralimab Combined With Apatinib and Irinotecan Hydrochloride for the Treatment of Advanced Alpha-fetoprotein-producing Gastric Cancer (AFPGC) [Phase 2]

  Phase 2 trial investigating a quadruple combination of Iparomlimab, Tuvonralimab, Apatinib, and Irinotecan hydrochloride for advanced Alpha-…

• CLINICAL_TRIALS research · 2025-12-16
  Clinical Trial Update: The GAstric Precancerous Conditions Study

  The GAstric Precancerous Conditions Study at Stanford is currently recruiting participants to study gastric precancerous conditions, includi…

• CLINICAL_TRIALS research · 2025-12-15
  Clinical Trial Update: Perioperative Therapies in Locally Advanced Unresectable Gastric Cancer [Phase 2]

  A Phase 2 clinical trial is currently recruiting to evaluate perioperative therapies for locally advanced unresectable gastric cancer.

• CLINICAL_TRIALS research · 2025-12-15
  Clinical Trial Update: Trastuzumab Deruxtecan(T-DXd) and Afatinib Combination in HER2-low Advanced Gastric Cancer [Phase 1, Phase 2]

  A Phase 1/2 clinical trial evaluating the combination of trastuzumab deruxtecan and afatinib for HER2-low advanced gastric cancer is current…

• CLINICAL_TRIALS research · 2025-12-12
  Clinical Trial Update: Claudin 18.2-Targeted Chimeric Antigen Receptor T-cells in Subjects With Unresectable, Locally Advanced, or Metastatic Gastric, Gastroesophageal Junction (GEJ), Esophageal, or Pancreatic Adenocarcinoma [Phase 1]

  Phase 1 clinical trial evaluating Claudin 18.2-targeted CAR-T cells in unresectable/locally advanced or metastatic gastric, gastroesophageal…

• CLINICAL_TRIALS research · 2025-12-11
  Clinical Trial Update: Intravital Microscopy in Human Solid Tumors [NA]

  Mayo Clinic is conducting a clinical trial using intravital microscopy in multiple solid tumors, currently recruiting.

• CLINICAL_TRIALS research · 2025-12-11
  Clinical Trial Update: Novel Humanized Ferritin-based NIR Fluorescent Molecular Probe for Identifying Tumor Margins in Gastric Tissue

  Clinical trial update on a novel ferritin-based near-infrared fluorescent probe to identify tumor margins in gastric tissue; the study is no…

• CLINICAL_TRIALS research · 2025-12-11
  Clinical Trial Update: A Study of MT-4561 in Patients With Various Advanced Solid Tumors [Phase 1, Phase 2]

  This trial update reports that MT-4561 is being studied in multiple advanced solid tumors across Phase 1/Phase 2 and is currently recruiting…

• CLINICAL_TRIALS research · 2025-12-10
  Clinical Trial Update: PIPAC for the Treatment of Peritoneal Carcinomatosis in Patients With Ovarian, Uterine, Appendiceal, Colorectal, or Gastric Cancer [Phase 1]

  Clinical trial update indicating a Phase 1 study of PIPAC (pressurized intraperitoneal aerosol chemotherapy) to treat peritoneal carcinomato…

• CLINICAL_TRIALS research · 2025-12-10
  Clinical Trial Update: Zanidatamab Combined With Chemotherapy as Neoadjuvant Therapy for HER2-high Expression G/GEJC [Phase 2]

  A Phase 2 neoadjuvant trial is evaluating Zanidatamab in combination with chemotherapy for HER2-high gastric/gastroesophageal junction adeno…