Gastric Adenocarcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-01-27Clinical Trial Update: A Study of Zolbetuximab (IMAB362) Plus CAPOX Compared With Placebo Plus CAPOX as First-line Treatment of Subjects With Claudin (CLDN) 18.2-positive, HER2-negative, Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma (GLOW). [Phase 3]
Phase 3 trial evaluating zolbetuximab plus CAPOX versus placebo plus CAPOX as first-line treatment for CLDN18.2-positive, HER2-negative loca…
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CLINICAL_TRIALS trial_result · 2025-01-24Clinical Trial Update: PI3Kβ Selective Inhibitor With Paclitaxel, Advanced Gastric Adenocarcinoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial sponsored by Yonsei University evaluated a PI3Kβ-selective inhibitor in combination with paclitaxel for advanced …
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CLINICAL_TRIALS trial_result · 2025-01-22Clinical Trial Update: Tucatinib, Trastuzumab, Ramucirumab, and Paclitaxel Versus Paclitaxel and Ramucirumab in Previously Treated HER2+ Gastroesophageal Cancer [Phase 2, Phase 3]
Clinical trial update reporting results from a Phase 2/3 study of tucatinib + trastuzumab + ramucirumab + paclitaxel vs paclitaxel + ramucir…
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CLINICAL_TRIALS trial_result · 2025-01-22Clinical Trial Update: NESC: Neoadjuvant Treatment of Gastric Adenocarcinoma [Phase 2]
A Phase 2 trial evaluating neoadjuvant treatment for gastric adenocarcinoma has completed.
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CLINICAL_TRIALS trial_result · 2025-01-17Clinical Trial Update: Phase II Randomized Trial of Bethesda Protocol Compared to Cambridge Method for Detection of Early Stage Gastric Cancer in CDH1 Mutation Carriers [Phase 2]
Phase II randomized trial comparing the Bethesda Protocol to the Cambridge Method for detection of early-stage gastric cancer in CDH1 mutati…
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CLINICAL_TRIALS trial_result · 2025-01-16Clinical Trial Update: Study to Test the Safety and Tolerability of PF-07062119 in Patients With Selected Advanced or Metastatic Gastrointestinal Tumors. [Phase 1]
A Phase 1 study of PF-07062119 in selected advanced or metastatic gastrointestinal tumors was terminated, with results posted.
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CLINICAL_TRIALS research · 2025-01-07Clinical Trial Update: Second-line Treatment With Serplulimab, Lenvatinib, and Paclitaxel in Advanced Gastric Cancer After Prior Immunotherapy [Phase 2]
A phase 2 clinical trial is evaluating the combination of serplulimab, lenvatinib, and paclitaxel as second-line therapy for advanced gastri…
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CLINICAL_TRIALS trial_result · 2024-12-27Clinical Trial Update: Neoadjuvant Combination Chemotherapy of DCS and DCF in Patients With Locally Advanced Gastric Adenocarcinoma [Phase 2]
This Phase 2 trial evaluated neoadjuvant chemotherapy using DCS and DCF regimens for locally advanced gastric adenocarcinoma and has complet…
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CLINICAL_TRIALS trial_result · 2024-12-27Clinical Trial Update: Preoperative Chemoradiotherapy for Locally Advanced Resectable Gastric Adenocarcinoma [Phase 2]
A Phase 2 clinical trial evaluating preoperative chemoradiotherapy for locally advanced resectable gastric adenocarcinoma has completed.
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CLINICAL_TRIALS trial_result · 2024-12-16Clinical Trial Update: BI-1607 in Combination with Trastuzumab in Subjects with HER2-positive Advanced Solid Tumors [Phase 1, Phase 2]
BI-1607 in combination with Trastuzumab for HER2-positive advanced solid tumors (Phase 1/2) has been terminated. The study included HER2-pos…
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CLINICAL_TRIALS trial_result · 2024-11-15Clinical Trial Update: Multimodal Model Predicts Recurrence
A clinical trial evaluating a multimodal model to predict recurrence in gastric adenocarcinoma has completed.
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CLINICAL_TRIALS trial_result · 2024-11-14Clinical Trial Update: Safety and Activity of IMAB362 in Combination With Zoledronic Acid and Interleukin-2 in CLDN18.2-positive Gastric Cancer [Phase 1]
Phase 1 study assessing safety and activity of IMAB362 (zolbetuximab) in combination with zoledronic acid and interleukin-2 in CLDN18.2-posi…
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CLINICAL_TRIALS trial_result · 2024-10-31Clinical Trial Update: CAPOX Plus Sintilimab and Bevacizumab Biosimilar (IBI305) for Neoadjuvant Treatment of Locally Advanced Gastric Cancer [Phase 2]
A Phase 2 clinical trial is investigating neoadjuvant CAPOX plus sintilimab and the bevacizumab biosimilar IBI305 for locally advanced gastr…
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CLINICAL_TRIALS research · 2024-10-24Clinical Trial Update: Oxaliplatin ± Nivolumab in Combination With Trifluridine/Tipiracil or 5-fluorouracile in Frail Patients With Advanced, Recurrent or Metastatic Gastric, Oesophageal or Gastroesophageal Junction Cancer [Phase 2]
Phase 2 trial assessing oxaliplatin with or without nivolumab in combination with trifluridine/tipiracil or 5-fluorouracil for frail patient…
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CLINICAL_TRIALS trial_result · 2024-10-23Clinical Trial Update: Study of INBRX-105 and INBRX-105 With Pembrolizumab in Patients With Solid Tumors Including Head and Neck Cancer [Phase 1]
This Phase 1 trial update reports termination of the INBRX-105 in combination with pembrolizumab across multiple solid tumors, including hea…
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CLINICAL_TRIALS trial_result · 2024-10-18Clinical Trial Update: Effect of High Protein ONS on Older Gastric Cancer Patients Receiving Neoadjuvant Chemotherapy [NA]
Clinical trial completed assessing the effect of a high-protein oral nutritional supplement in older patients with locally advanced gastric …
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CLINICAL_TRIALS trial_result · 2024-10-15Clinical Trial Update: Study of JK08 in Patients with Unresectable Locally Advanced or Metastatic Cancer [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial of JK08 for unresectable locally advanced or metastatic cancer conducted by Salubris Biotherapeutics is cur…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Heated Mitomycin and Cisplatin During Surgery in Treating Patients With Stomach or Gastroesophageal Cancer [Phase 2]
This Phase 2 trial reports results for heated Mitomycin C and Cisplatin administered during surgery for gastric and gastroesophageal junctio…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) in Gastric Carcinomatosis. Phase II Randomized Study [Phase 2]
Phase II randomized trial evaluating pressurized intraperitoneal aerosol chemotherapy (PIPAC) in gastric carcinomatosis due to gastric adeno…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: A Study of Anti-PD-1 and LAG-3 Bispecific Antibody(AK129) Combined With Chemotherapy With or Without Cadonilimab in the First-line Treatment of Unresectable Locally Advanced or Metastatic G/ GEJ Adenocarcinoma [Phase 1, Phase 2]
A clinical trial update describes a Phase 1/2 study of AK129, an anti-PD-1 and LAG-3 bispecific antibody, combined with chemotherapy with or…
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CLINICAL_TRIALS research · 2024-09-05Clinical Trial Update: A PhaseⅠ/Ⅱ Study of Simmitinib or Irinotecan Liposomes Combined With DP303c in Gastric Adenocarcinoma or Gastroesophageal Junction Adenocarcinoma [Phase 1, Phase 2]
This clinical trial update describes a Phase I/II study evaluating Simmitinib or irinotecan liposomes in combination with DP303c for HER2-ex…
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CLINICAL_TRIALS research · 2024-08-27Clinical Trial Update: A Randomized, Multicenter Phase II Basket Study of Hypofractionated Radiotherapy/Stereotactic Body Radiotherapy Followed by Immunotherapy-Based Systemic Therapy +/- L. Rhamnosus M9 for the First-Line Treatment of Advanced Digestive System Malignancies. [NA]
A multicenter Phase II basket trial at Zhejiang Cancer Hospital is evaluating hypofractionated radiotherapy or SBRT followed by immunotherap…
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CLINICAL_TRIALS trial_result · 2024-08-02Clinical Trial Update: A Study of AK104, a PD-1/CTLA-4 Bispecific Antibody, for Advanced Solid Tumors or With mXELOX/XELOX as First-line Therapy for Advanced Gastric or GEJ Adenocarcinoma [Phase 1, Phase 2]
Update on AK104, a PD-1/CTLA-4 bispecific antibody, evaluated in Phase 1/2 for advanced solid tumors and as first-line therapy with mXELOX/X…
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CLINICAL_TRIALS research · 2024-08-02Clinical Trial Update: Anti-PD-1 and CapOx for the First-line Treatment of dMMR Esophagogastric Cancer (AuspiCiOus) [Phase 2]
Phase 2 clinical trial evaluating a PD-1 inhibitor with Capecitabine and Oxaliplatin (CapOx) as first-line therapy for dMMR esophagogastric …
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CLINICAL_TRIALS trial_result · 2024-07-31Clinical Trial Update: A Study of Ramucirumab Plus Pembrolizumab in Participants With Gastric or GEJ Adenocarcinoma, NSCLC, Transitional Cell Carcinoma of the Urothelium, or Biliary Tract Cancer [Phase 1]
Phase 1 trial evaluating the combination of ramucirumab and pembrolizumab in gastric/GEJ adenocarcinoma, non-small cell lung cancer, urothel…