Gastric Adenocarcinoma

CLINICAL_TRIALS trial_result · 2025-11-19

Clinical Trial Update: A Study of AK104 in the First-line Treatment of Locally Advanced Unresectable or Metastatic G/GEJ Adenocarcinoma [Phase 3]

A Phase 3 trial evaluating AK104 as first-line therapy for locally advanced unresectable or metastatic gastric adenocarcinoma and gastroesop…

CLINICAL_TRIALS research · 2025-11-19

Clinical Trial Update: A Phase II Study of Perioperative Paclitaxel in Patients With Gastric Adenocarcinoma and Carcinomatosis or Positive Cytology [Phase 2]

A Phase II clinical trial evaluating perioperative paclitaxel in patients with gastric adenocarcinoma and peritoneal carcinomatosis or posit…

CLINICAL_TRIALS research · 2025-11-17

Clinical Trial Update: A Study of BL-M07D1 Versus Investigator's Choice of Chemotherapy in Patients With HER2-positive Locally Advanced or Metastatic Gastric or Gastro-esophageal Junction Adenocarcinoma [Phase 3]

This is a Phase 3 clinical trial comparing BL-M07D1 to investigator's choice chemotherapy in HER2-positive locally advanced or metastatic ga…

CLINICAL_TRIALS research · 2025-11-10

Clinical Trial Update: Nab-Paclitaxel PIPAC in Combination With Paclitaxel and Ramucirumab for the Treatment of Stomach Cancer With Peritoneal Metastases [Phase 1]

This is a Phase 1 clinical trial evaluating nab-paclitaxel in combination with paclitaxel and ramucirumab for clinical stage IVB gastric can…

CLINICAL_TRIALS research · 2025-10-23

Clinical Trial Update: A Phase III Randomized Study in CLDN18.2-positive Unresectable Locally Advanced Gastric Cancer Patients [Phase 3]

A Phase III randomized trial targeting CLDN18.2 in patients with unresectable, locally advanced gastric cancer is currently recruiting.

CLINICAL_TRIALS research · 2025-10-16

Clinical Trial Update: Tadalafil Effect + Chemotherapy in Resectable Gastric/GEJ Cancer [Phase 2]

Phase 2 trial evaluating tadalafil in combination with chemotherapy for resectable gastric or gastroesophageal junction adenocarcinoma; curr…

CLINICAL_TRIALS trial_result · 2025-10-09

Clinical Trial Update: A Study of DKN-01 in Combination With Tislelizumab ± Chemotherapy in Patients With Gastric or Gastroesophageal Cancer [Phase 2]

Phase 2 study of DKN-01 in combination with tislelizumab, with or without chemotherapy, in gastric and gastroesophageal cancers was terminat…

CLINICAL_TRIALS research · 2025-09-17

Clinical Trial Update: Gender Differences in Gastric Cancer Care and Its Adherence to Guidelines in Germany

An observational clinical trial in Germany assessing gender differences in the management of gastric adenocarcinoma and adherence to clinica…

CLINICAL_TRIALS trial_result · 2025-09-12

Clinical Trial Update: Phase 1a/1b Study of TPST-1495 as a Single Agent and in Combination With Pembrolizumab in Subjects With Solid Tumors [Phase 1]

Phase 1a/1b study of TPST-1495 as monotherapy and in combination with pembrolizumab has completed status, spanning multiple solid tumors inc…

CLINICAL_TRIALS research · 2025-09-10

Clinical Trial Update: Early Access Program for Zolbetuximab

It provides an update on the Early Access Program for zolbetuximab in patients with locally advanced unresectable or metastatic gastric or g…

CLINICAL_TRIALS research · 2025-09-05

Clinical Trial Update: Conversion Therapy Plus Surgery and Radiotherapy for Retroperitoneal Nodal Metastases in Gastric Cancer [Phase 2]

A Phase 2 clinical trial investigating conversion therapy plus surgery and radiotherapy for gastric cancer with retroperitoneal nodal metast…

CLINICAL_TRIALS trial_result · 2025-09-03

Clinical Trial Update: Study of SHR-8068 Combined With Adebrelimab and Platinum-containing Chemotherapy in the Treatment of Advanced Gastric and Esophageal Cancer [Phase 2]

A Phase 2 clinical trial update evaluating SHR-8068 in combination with Adebrelimab and platinum-based chemotherapy for advanced gastric ade…

CLINICAL_TRIALS research · 2025-08-27

Clinical Trial Update: [18F]F-FAPI PET/CT and Laparoscopy in Staging Advanced Gastric Cancer [Phase 2, Phase 3]

This Phase 2/Phase 3 trial from Leiden University Medical Center is evaluating [18F]F-FAPI PET/CT with laparoscopy for staging locally advan…

CLINICAL_TRIALS research · 2025-08-22

Clinical Trial Update: A Vaccine (Ad5.F35-hGCC-PADRE) for the Treatment of Gastrointestinal Adenocarcinoma [Phase 2]

Phase 2 clinical trial update on the Ad5.F35-hGCC-PADRE cancer vaccine for pancreatic, colorectal, gastric, and esophageal adenocarcinomas; …

CLINICAL_TRIALS research · 2025-08-07

Clinical Trial Update: A Study of Evorpacept (ALX148) in Patients With Advanced HER2+ Gastric Cancer (ASPEN-06) [Phase 2, Phase 3]

Clinical trial update on evorpacept (ALX148) for advanced HER2-positive gastric cancer (ASPEN-06) noting that Phase 2 and Phase 3 cohorts ar…

CLINICAL_TRIALS trial_result · 2025-08-03

Clinical Trial Update: A Study of DKN-01 in Combination With Paclitaxel or Pembrolizumab [Phase 1]

Phase 1 study of DKN-01 with paclitaxel or pembrolizumab in esophageal and gastroesophageal cancers has been completed.

CLINICAL_TRIALS research · 2025-08-03

Clinical Trial Update: A Study of TRK-950 When Used in Combination With Ramucirumab and Paclitaxel in Patients With Gastric Cancer [Phase 2]

Phase 2 clinical trial evaluating TRK-950 in combination with ramucirumab and paclitaxel for gastric cancer in recruiting status.

CLINICAL_TRIALS research · 2025-08-03

Clinical Trial Update: Expanded Access Use of DKN-01 for the Treatment of Advanced Solid Tumors

Expanded-access update for Leap Therapeutics' DKN-01 in advanced solid tumors, noting the program is no longer available and targeting multi…

CLINICAL_TRIALS research · 2025-08-01

Clinical Trial Update: Shenqi Fuwei Mixture Combined With Chemotherapy Neoadjuvant Therapy for Locally Advanced Gastric Cancer [NA]

A clinical trial (NCT07098026) is evaluating Shenqi Fuwei Mixture combined with chemotherapy as neoadjuvant therapy for locally advanced gas…

CLINICAL_TRIALS research · 2025-07-29

Clinical Trial Update: Efficacy and Safety of AK112 Combined Chemotherapy as Neoadjuvant Treatment for Signet Ring Cell-containing G/GEJ Adenocarcinoma [Phase 2]

A Phase 2 trial is evaluating AK112 in combination with chemotherapy as neoadjuvant therapy for signet ring cell-containing gastric or gastr…

CLINICAL_TRIALS trial_result · 2025-06-15

Clinical Trial Update: Efficacy and Safety of IMAB362 in Combination With the EOX Regimen for CLDN18.2-positive Gastric Cancer [Phase 2]

Phase 2 trial evaluating IMAB362 (zolbetuximab) in combination with the EOX chemotherapy regimen for CLDN18.2-positive gastric, gastroesopha…

CLINICAL_TRIALS research · 2025-06-10

Clinical Trial Update: Planning Treatment for Oesophago-gastric Cancer: a Maintenance Therapy Trial [Phase 2]

A Phase 2 maintenance therapy trial for oesophago-gastric cancer is active but not recruiting, focusing on esophageal, gastroesophageal junc…

CLINICAL_TRIALS research · 2025-06-05

Clinical Trial Update: Study to Evaluate the Efficacy, Safety and Pharmacokinetics of CT041 Autologous CAR T-cell Injection [Phase 1, Phase 2]

This update describes an ongoing Phase 1/2 clinical trial evaluating CT041 autologous CAR T-cell therapy for gastric adenocarcinoma, gastroe…

CLINICAL_TRIALS research · 2025-06-02

Clinical Trial Update: Timing of Minimally Invasive Local Treatment After First-Line Systemic Therapy in Oligometastatic Esophageal or Gastric Adenocarcinoma [Phase 2, Phase 3]

This clinical trial update outlines a Phase 2/Phase 3 study evaluating the timing of minimally invasive local treatment following first-line…

CLINICAL_TRIALS research · 2025-05-30

Clinical Trial Update: Relationship Between Perioperative Treatment Efficacy and The Tumor Microenvironment for Locally Advanced Resectable Gastric Cancer.

This clinical trial update discusses how perioperative treatment efficacy may be influenced by the tumor microenvironment in locally advance…

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