Gastric Adenocarcinoma

Top drugs studied for this disease

All Approvals Safety alerts Label changes Trial results Research Guidance Withdrawals

CLINICAL_TRIALS trial_result · 2023-02-21
Clinical Trial Update: Study Title: Peri-operative Immuno-Chemotherapy in Operable Oesophageal and Gastric Cancer [Phase 2]
Phase 2 clinical trial evaluating peri-operative immunotherapy with chemotherapy in operable gastric and oesophageal adenocarcinoma. Status …
CLINICAL_TRIALS trial_result · 2023-01-31
Clinical Trial Update: A Study of Docetaxel for Injection (Albumin-bound) in Patients With Gastric Cancer [Phase 2]
Phase 2 trial update for docetaxel albumin-bound in gastric cancer (gastric adenocarcinoma and adenocarcinoma of GEJ) is ongoing with unknow…
CLINICAL_TRIALS trial_result · 2022-10-26
Clinical Trial Update: Study to Evaluate Ibrutinib Combination Therapy in Patients With Selected Gastrointestinal and Genitourinary Tumors [Phase 1, Phase 2]
Phase 1/2 trial evaluating aibrutinib combination therapy in selected gastrointestinal and genitourinary tumors has completed with results p…
CLINICAL_TRIALS trial_result · 2022-10-26
Clinical Trial Update: A Biomarker Study for Predicting the Efficacy of Neoadjuvant Sintilimab Plus SOX for Gastric Adenocarcinoma. [Phase 2]
A Phase 2 biomarker study evaluating the predictive value of biomarkers for the efficacy of neoadjuvant sintilimab plus SOX in gastric adeno…
CLINICAL_TRIALS trial_result · 2022-08-08
Clinical Trial Update: A Study of Pembrolizumab (MK-3475) in Participants With Recurrent or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma (MK-3475-059/KEYNOTE-059) [Phase 2]
Phase 2 trial of pembrolizumab in recurrent or metastatic gastric or gastroesophageal junction adenocarcinoma has completed with results pos…
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CLINICAL_TRIALS trial_result · 2022-07-08
Clinical Trial Update: A Study to Evaluate Rivoceranib Plus Best Supportive Care Compared to Placebo Plus Best Supportive Care in Participants With Gastric Cancer [Phase 3]
Phase 3 trial evaluating rivoceranib plus best supportive care versus placebo plus best supportive care in gastric cancer; trial completed w…
CLINICAL_TRIALS trial_result · 2022-06-30
Clinical Trial Update: Pembrolizumab and Palliative Radiation Therapy in Treating Patients With Metastatic Esophagus, Stomach, or Gastroesophageal Junction Cancer [Phase 2]
A Phase 2 trial evaluating pembrolizumab combined with palliative radiation therapy in patients with metastatic cancers of the esophagus, st…
CLINICAL_TRIALS trial_result · 2022-06-15
Clinical Trial Update: Study of AZD1775 in Combination With Paclitaxel, in Advanced Gastric Adenocarcinoma Patients Harboring TP53 Mutation as a Second-line Chemotherapy [Phase 2]
Phase 2 trial update of AZD1775 combined with paclitaxel in advanced gastric adenocarcinoma with TP53 mutation as second-line therapy has co…
CLINICAL_TRIALS trial_result · 2022-06-15
Clinical Trial Update: As a Second-line Treatment for Metastatic Gastric Adenocarcinoma Patients, the Safety and Effective of Vactosertib Administration in Combination With Paclitaxel+Ramucirumab is Evaluated, and a Phase 2a Clinical Trial to Biomarkers [Phase 2]
Phase 2a trial evaluating safety and efficacy of Vactosertib with paclitaxel and ramucirumab as a second-line treatment for metastatic gastr…
CLINICAL_TRIALS trial_result · 2022-06-15
Clinical Trial Update: Study of AZD6094 (Volitinib) in Advanced Gastric Adenocarcinoma Patients With MET Amplification as a Third-line Treatment [Phase 2]
A Phase 2 trial evaluating AZD6094 (Volitinib) in advanced gastric adenocarcinoma with MET amplification as a third-line treatment has been …
CLINICAL_TRIALS trial_result · 2022-06-15
Clinical Trial Update: Phase Ib, Single-arm Study of AZD6094 (Volitinib) in Combination With Docetaxel, in Any Solid Cancer and Sequential Phase II, Single-arm Study of AZD6094 (Volitinib) in Combination With Docetaxel in Advanced Gastric Adenocarcinoma Patients With MET Amplification as a Second Line Treatment [Phase 1, Phase 2]
Phase Ib/Phase II single-arm studies evaluating AZD6094 (Volitinib) with Docetaxel in solid cancers, and in advanced gastric adenocarcinoma …
CLINICAL_TRIALS trial_result · 2022-06-15
Clinical Trial Update: This Study is a Phase II Study of AZD6738 in Combination With Durvalumab in Patients With Solid Tumor (Cohort A (N=30): GC Who Have Failed Secondary Chemotherapy Treatments Regimen; Cohort B (B=30): Melanoma Patients Who Have Failed to IO) [Phase 2]
Phase II study evaluating AZD6738 in combination with durvalumab in gastric adenocarcinoma and malignant melanoma (Cohort A: gastric cancer …
CLINICAL_TRIALS trial_result · 2022-04-22
Clinical Trial Update: Camrelizumab Combined With Apatinib Versus Apatinib Alone in the Third-line Treatment of Metastatic Gastric Cancer [Phase 2]
Phase 2 trial evaluating camrelizumab plus apatinib versus apatinib alone as third-line treatment for metastatic gastric cancer, status curr…
CLINICAL_TRIALS trial_result · 2022-04-06
Clinical Trial Update: SOX Combined With Sintilimab and Trastuzumab Versus SOX Regimen in the Perioperative Treatment of HER2-positive Locally Advanced Gastric Adenocarcinoma [Phase 2]
Phase 2 trial evaluating SOX chemotherapy combined with sintilimab and trastuzumab versus SOX alone in perioperative treatment of HER2-posit…
CLINICAL_TRIALS trial_result · 2022-03-08
Clinical Trial Update: Study Evaluating Neoadjuvant Immunotherapy Increasing CD8+ Cell Infiltration in Advance Gastric Adenocarcinoma [Phase 3]
A Phase 3 trial evaluating neoadjuvant immunotherapy to increase CD8+ tumor-infiltrating lymphocytes in advanced gastric adenocarcinoma; sta…
CLINICAL_TRIALS trial_result · 2022-02-17
Clinical Trial Update: PEN-866 in Patients With Advanced Solid Malignancies [Phase 1, Phase 2]
Clinical trial update for PEN-866 across multiple phases investigating advanced solid malignancies, including endometrial adenocarcinoma and…
CLINICAL_TRIALS trial_result · 2022-01-12
Clinical Trial Update: DS-8201a in HER2-positive Gastric Cancer That Cannot Be Surgically Removed or Has Spread (DESTINY-Gastric02) [Phase 2]
The DESTINY-Gastric02 Phase 2 trial of DS-8201a (trastuzumab deruxtecan) in HER2-positive unresectable or metastatic gastric cancer has comp…
CLINICAL_TRIALS trial_result · 2022-01-11
Clinical Trial Update: Clinical Study of Camrelizumab Combined With SOX in the Adjuvant Treatment of Advanced Gastric Adenocarcinoma or Gastric Esophageal Junction Adenocarcinoma [Phase 2]
Phase 2 trial evaluating camrelizumab combined with SOX as adjuvant treatment for advanced gastric adenocarcinoma or gastroesophageal juncti…
CLINICAL_TRIALS trial_result · 2021-12-13
Clinical Trial Update: The Study to Evaluate Toripalimab (JS001) in Patients With Advanced GC, ESCC, NPC, HNSCC [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating toripalimab (JS001) in advanced gastric cancer and multiple squamous cell carcinomas including esophagea…
CLINICAL_TRIALS trial_result · 2021-08-31
Clinical Trial Update: A Study of LY3435151 in Participants With Solid Tumors [Phase 1]
Phase 1 study of LY3435151 in solid tumors, including triple-negative breast cancer, terminated with results posted.
CLINICAL_TRIALS trial_result · 2021-08-24
Clinical Trial Update: PD-1 Monoclonal Antibody Combined With FLOT Regimen for Neoadjuvant Therapy of Gastric Adenocarcinoma [Phase 2]
Phase 2 trial investigating PD-1 monoclonal antibody with FLOT chemotherapy as neoadjuvant therapy for gastric adenocarcinoma and tumors at …
CLINICAL_TRIALS trial_result · 2021-08-03
Clinical Trial Update: A Study of Paclitaxel With or Without Ramucirumab (LY3009806) in Participants With Gastric or Gastroesophageal Cancer [Phase 3]
Phase 3 trial assessing paclitaxel with or without ramucirumab in gastric or gastroesophageal junction adenocarcinoma has completed with res…
CLINICAL_TRIALS trial_result · 2021-06-14
Clinical Trial Update: DS-8201a in Patients With Cancer That Tests Positive for Human Epidermal Growth Factor Receptor 2 (HER2) Protein [Phase 1]
Phase 1 clinical trial update for DS-8201a in patients with HER2-positive cancers completed with results posted in 2021.
CLINICAL_TRIALS trial_result · 2021-06-08
Clinical Trial Update: Study of Vismodegib in Advanced Gastric Adenocarcinoma Patients With SMO Overexpression [Phase 2]
Phase 2 trial update of vismodegib in advanced gastric adenocarcinoma with SMO overexpression completed.
CLINICAL_TRIALS trial_result · 2021-05-17
Clinical Trial Update: Apatinib Plus Camrelizumab Combined With Docetaxel and S1 in First-line Treatment for Metastatic Gastric Cancer [Phase 2]
Phase 2 trial evaluating apatinib plus camrelizumab with docetaxel and S1 as first-line therapy for metastatic gastric/gastroesophageal junc…