Gastric Adenocarcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-03-27Clinical Trial Update: OPPOSITE: Outcome Prediction of Systemic Treatment in Esophagogastric Carcinoma [NA]
Clinical trial OPPOSITE, studying outcome prediction of systemic treatment in esophagogastric carcinoma, has completed. The sponsor is Unive…
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CLINICAL_TRIALS trial_result · 2025-03-21Clinical Trial Update: Oral STAT3 Inhibitor, TTI-101, in Patients With Advanced Cancers [Phase 1]
Phase 1 study of the oral STAT3 inhibitor TTI-101 in patients with advanced cancers has completed, with enrollment across multiple tumor typ…
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CLINICAL_TRIALS trial_result · 2025-03-19Clinical Trial Update: Safety and Efficacy of Single or Reduced Ports Laparoscopic Gastrectomy for Advanced Gastric Cancer (SPACE-01) [NA]
This clinical trial update describes SPACE-01, a study evaluating single- or reduced-port laparoscopic gastrectomy for advanced gastric canc…
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CLINICAL_TRIALS trial_result · 2025-03-14Clinical Trial Update: SL-279252 (PD1-Fc-OX40L) in Subjects With Advanced Solid Tumors or Lymphomas [Phase 1]
Phase 1 trial evaluating SL-279252, a PD-1-Fc-OX40L fusion protein, in adults with advanced solid tumors or lymphomas has been completed wit…
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CLINICAL_TRIALS trial_result · 2025-03-12Clinical Trial Update: Conversion Effects of PD-1 Antibody Camrelizumab Combined With Nab-POF Regimen Chemotherpy in Patients With Initially Unresectable Locally Advanced or Limited Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma：FDZL-GC001 Trial [Phase 2]
Phase 2 trial (NCT04510064) evaluated camrelizumab combined with nab-POF chemotherapy in patients with initially unresectable locally advanc…
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CLINICAL_TRIALS trial_result · 2025-03-10Clinical Trial Update: A Study of Ladiratuzumab Vedotin in Advanced Solid Tumors [Phase 2]
Phase 2 trial of ladiratuzumab vedotin in multiple advanced solid tumors was terminated, with results posted in March 2025.
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CLINICAL_TRIALS trial_result · 2025-02-26Clinical Trial Update: A Study to Compare Zolbetuximab (IMAB362) and Chemotherapy With Placebo and Chemotherapy in Adults With Gastric Cancer. [Phase 3]
Phase 3 trial update comparing zolbetuximab plus chemotherapy versus placebo plus chemotherapy in adults with gastric and gastroesophageal j…
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CLINICAL_TRIALS trial_result · 2025-02-19Clinical Trial Update: Heated Intraperitoneal Chemotherapy and Gastrectomy for Gastric Cancer With Positive Peritoneal Cytology [Phase 2]
This document reports the completion of a Phase 2 trial evaluating heated intraperitoneal chemotherapy plus gastrectomy for gastric cancer w…
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CLINICAL_TRIALS trial_result · 2025-01-27Clinical Trial Update: A Study of Zolbetuximab (IMAB362) Plus CAPOX Compared With Placebo Plus CAPOX as First-line Treatment of Subjects With Claudin (CLDN) 18.2-positive, HER2-negative, Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma (GLOW). [Phase 3]
A phase 3 trial (GLOW) evaluating zolbetuximab plus CAPOX versus placebo plus CAPOX in CLDN18.2-positive, HER2-negative gastric/GEJ adenocar…
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CLINICAL_TRIALS trial_result · 2025-01-27Clinical Trial Update: A Study of Zolbetuximab (IMAB362) Plus CAPOX Compared With Placebo Plus CAPOX as First-line Treatment of Subjects With Claudin (CLDN) 18.2-positive, HER2-negative, Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma (GLOW). [Phase 3]
Phase 3 trial evaluating zolbetuximab plus CAPOX versus placebo plus CAPOX as first-line treatment for CLDN18.2-positive, HER2-negative loca…
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CLINICAL_TRIALS trial_result · 2025-01-24Clinical Trial Update: PI3Kβ Selective Inhibitor With Paclitaxel, Advanced Gastric Adenocarcinoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial sponsored by Yonsei University evaluated a PI3Kβ-selective inhibitor in combination with paclitaxel for advanced …
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CLINICAL_TRIALS trial_result · 2025-01-22Clinical Trial Update: Tucatinib, Trastuzumab, Ramucirumab, and Paclitaxel Versus Paclitaxel and Ramucirumab in Previously Treated HER2+ Gastroesophageal Cancer [Phase 2, Phase 3]
Clinical trial update reporting results from a Phase 2/3 study of tucatinib + trastuzumab + ramucirumab + paclitaxel vs paclitaxel + ramucir…
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CLINICAL_TRIALS trial_result · 2025-01-22Clinical Trial Update: NESC: Neoadjuvant Treatment of Gastric Adenocarcinoma [Phase 2]
A Phase 2 trial evaluating neoadjuvant treatment for gastric adenocarcinoma has completed.
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CLINICAL_TRIALS trial_result · 2025-01-17Clinical Trial Update: Phase II Randomized Trial of Bethesda Protocol Compared to Cambridge Method for Detection of Early Stage Gastric Cancer in CDH1 Mutation Carriers [Phase 2]
Phase II randomized trial comparing the Bethesda Protocol to the Cambridge Method for detection of early-stage gastric cancer in CDH1 mutati…
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CLINICAL_TRIALS trial_result · 2025-01-16Clinical Trial Update: Study to Test the Safety and Tolerability of PF-07062119 in Patients With Selected Advanced or Metastatic Gastrointestinal Tumors. [Phase 1]
A Phase 1 study of PF-07062119 in selected advanced or metastatic gastrointestinal tumors was terminated, with results posted.
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CLINICAL_TRIALS trial_result · 2024-12-27Clinical Trial Update: Neoadjuvant Combination Chemotherapy of DCS and DCF in Patients With Locally Advanced Gastric Adenocarcinoma [Phase 2]
This Phase 2 trial evaluated neoadjuvant chemotherapy using DCS and DCF regimens for locally advanced gastric adenocarcinoma and has complet…
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CLINICAL_TRIALS trial_result · 2024-12-27Clinical Trial Update: Preoperative Chemoradiotherapy for Locally Advanced Resectable Gastric Adenocarcinoma [Phase 2]
A Phase 2 clinical trial evaluating preoperative chemoradiotherapy for locally advanced resectable gastric adenocarcinoma has completed.
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CLINICAL_TRIALS trial_result · 2024-12-16Clinical Trial Update: BI-1607 in Combination with Trastuzumab in Subjects with HER2-positive Advanced Solid Tumors [Phase 1, Phase 2]
BI-1607 in combination with Trastuzumab for HER2-positive advanced solid tumors (Phase 1/2) has been terminated. The study included HER2-pos…
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CLINICAL_TRIALS trial_result · 2024-11-15Clinical Trial Update: Multimodal Model Predicts Recurrence
A clinical trial evaluating a multimodal model to predict recurrence in gastric adenocarcinoma has completed.
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CLINICAL_TRIALS trial_result · 2024-11-14Clinical Trial Update: Safety and Activity of IMAB362 in Combination With Zoledronic Acid and Interleukin-2 in CLDN18.2-positive Gastric Cancer [Phase 1]
Phase 1 study assessing safety and activity of IMAB362 (zolbetuximab) in combination with zoledronic acid and interleukin-2 in CLDN18.2-posi…
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CLINICAL_TRIALS trial_result · 2024-10-31Clinical Trial Update: CAPOX Plus Sintilimab and Bevacizumab Biosimilar (IBI305) for Neoadjuvant Treatment of Locally Advanced Gastric Cancer [Phase 2]
A Phase 2 clinical trial is investigating neoadjuvant CAPOX plus sintilimab and the bevacizumab biosimilar IBI305 for locally advanced gastr…
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CLINICAL_TRIALS trial_result · 2024-10-23Clinical Trial Update: Study of INBRX-105 and INBRX-105 With Pembrolizumab in Patients With Solid Tumors Including Head and Neck Cancer [Phase 1]
This Phase 1 trial update reports termination of the INBRX-105 in combination with pembrolizumab across multiple solid tumors, including hea…
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CLINICAL_TRIALS trial_result · 2024-10-18Clinical Trial Update: Effect of High Protein ONS on Older Gastric Cancer Patients Receiving Neoadjuvant Chemotherapy [NA]
Clinical trial completed assessing the effect of a high-protein oral nutritional supplement in older patients with locally advanced gastric …
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CLINICAL_TRIALS trial_result · 2024-10-15Clinical Trial Update: Study of JK08 in Patients with Unresectable Locally Advanced or Metastatic Cancer [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial of JK08 for unresectable locally advanced or metastatic cancer conducted by Salubris Biotherapeutics is cur…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Heated Mitomycin and Cisplatin During Surgery in Treating Patients With Stomach or Gastroesophageal Cancer [Phase 2]
This Phase 2 trial reports results for heated Mitomycin C and Cisplatin administered during surgery for gastric and gastroesophageal junctio…