Follicular Lymphoma

• CLINICAL_TRIALS research · 2026-01-20
  Clinical Trial Update: Study of Kappa Chimeric Antigen Receptor (CAR) T Lymphocytes Co-Expressing the Kappa and CD28 CARs for Relapsed/Refractory Kappa+ Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma. [Phase 1]

  Phase 1 study evaluating T cells engineered to co-express kappa and CD28 CARs for relapsed/refractory kappa+ non-Hodgkin lymphoma and chroni…

• CLINICAL_TRIALS research · 2026-01-16
  Clinical Trial Update: A Study to Assess the Adverse Events, Change in Disease Activity, and How Intravenously Infused ABBV-319 Moves Through the Bodies of Adult Participants With Relapsed or Refractory (R/R) Diffuse Large B-cell Lymphoma (DLBCL), Follicular Lymphoma (FL), or Chronic Lymphocytic Leukemia (CLL) [Phase 1]

  Phase 1 clinical trial update for ABBV-319 evaluating adverse events, change in disease activity, and pharmacokinetics in adults with relaps…

• CLINICAL_TRIALS research · 2026-01-15
  Clinical Trial Update: huCART19-IL18-eDHFR Cells in Relapsed/Refractory Follicular Lymphoma [Phase 1]

  Phase 1 clinical trial evaluating huCART19-IL18-eDHFR cells for relapsed or refractory follicular lymphoma. The study status is not yet recr…

• CLINICAL_TRIALS other · 2026-01-15
  Clinical Trial Update: Ph I/II Study of E7777 Prior to CAR-T for R/R LBCL [Phase 1, Phase 2]

  A Phase 1/2 study of E7777 for relapsed or refractory diffuse large B-cell lymphoma is suspended; no results are provided in this update.

• CLINICAL_TRIALS research · 2026-01-14
  Clinical Trial Update: Anti-CD19 Chimeric Antigen Receptor T Cells for Treatment of Relapsed or Refractory Non-Hodgkin Lymphoma [Phase 1]

  This is a Phase 1 trial evaluating anti-CD19 CAR-T cell therapy for relapsed or refractory non-Hodgkin lymphoma. The study is currently recr…

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• CLINICAL_TRIALS research · 2026-01-08
  Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Golcadomide in Combination With Rituximab in Participants With Newly Diagnosed Advanced Stage Follicular Lymphoma [Phase 2]

  This entry describes a Phase 2 trial evaluating golcadomide in combination with rituximab for newly diagnosed advanced-stage follicular lymp…

• CLINICAL_TRIALS trial_result · 2026-01-07
  Clinical Trial Update: Ultra Low Dose Orbital Radiation Therapy in Treating Patients With Stage I-IV Indolent B-cell Lymphoma or Mantle Cell Lymphoma [Phase 2]

  Phase 2 trial evaluating ultra-low-dose orbital radiation therapy for Stage I-IV indolent B-cell non-Hodgkin lymphoma and mantle cell lympho…

• CLINICAL_TRIALS trial_result · 2026-01-02
  Clinical Trial Update: A Study of Tazemetostat on Safety in Participants With Relapsed or Refractory Follicular Lymphoma With Enhancer of Zeste Homolog 2 (EZH2) Gene Mutation in Japan

  A clinical trial update for safety evaluation of Tazemetostat in Japanese participants with relapsed or refractory follicular lymphoma harbo…

• CLINICAL_TRIALS research · 2025-12-31
  Clinical Trial Update: A Study of Mosunetuzumab Alone or With Zanubrutinib in People With Follicular Lymphoma [Phase 2]

  A Phase 2 clinical trial is evaluating mosunetuzumab alone or in combination with zanubrutinib in people with follicular lymphoma and other …

• CLINICAL_TRIALS trial_result · 2025-12-30
  Clinical Trial Update: Mosunetuzumab With Lenalidomide Augmentation as First-line Therapy for Follicular and Marginal Zone Lymphoma [Phase 2]

  A Phase 2 trial is evaluating mosunetuzumab with lenalidomide augmentation as first-line therapy for follicular lymphoma and marginal zone l…

• CLINICAL_TRIALS research · 2025-12-30
  Clinical Trial Update: Copanlisib and Nivolumab in Treating Patients With Richter's Transformation or Transformed Indolent Non-Hodgkin Lymphoma [Phase 1]

  A Phase 1 trial is evaluating the combination of copanlisib and nivolumab in patients with Richter's transformation or transformed indolent …

• CLINICAL_TRIALS research · 2025-12-29
  Clinical Trial Update: Multilayer Biological Characterization of Advanced Follicular Lymphoma: a Translational Study From FIL_FOLL12 Trial

  A translational study from the FIL_FOLL12 trial is underway to perform multilayer biological characterization of advanced follicular lymphom…

• CLINICAL_TRIALS research · 2025-12-24
  Clinical Trial Update: Comparison Between Local Radiotherapy Alone or Combined With Obinutuzumab in Early Stage Follicular Lymphoma: the GAZEBO Trial From the Fondazione Italiana Linfomi [Phase 3]

  Phase 3 trial investigating local radiotherapy alone versus radiotherapy combined with obinutuzumab in early-stage follicular lymphoma is cu…

• CLINICAL_TRIALS research · 2025-12-24
  Clinical Trial Update: A Dose Escalation and Dose Expansion Study of Intratumoral ONM-501 Alone and in Combination With Cemiplimab in Patients With Advanced Solid Tumors and Lymphomas. [Phase 1]

  This is a Phase 1 dose-escalation and expansion study evaluating intratumoral ONM-501 alone and in combination with cemiplimab in patients w…

• CLINICAL_TRIALS trial_result · 2025-12-23
  Clinical Trial Update: A Study of Axicabtagene Ciloleucel in Participants With Relapsed/Refractory Indolent Non-Hodgkin Lymphoma [Phase 2]

  Phase 2 clinical trial of Axicabtagene Ciloleucel in relapsed/refractory indolent non-Hodgkin lymphoma (follicular and marginal zone lymphom…

• CLINICAL_TRIALS trial_result · 2025-12-23
  Clinical Trial Update: A Compassionate Use (CU) Program of Odronextamab

  Compassionate-use program update for odronextamab in relapsed or refractory B-cell lymphomas, including follicular lymphoma and diffuse larg…

• CLINICAL_TRIALS research · 2025-12-23
  Clinical Trial Update: Zanubrutinib, Obinutuzumab Combined With Lenalidomide (ZGR) for the Treatment of Untreated Follicular Lymphoma [Phase 2]

  This document outlines a Phase 2 clinical trial testing a triple combination of zanubrutinib, obinutuzumab, and lenalidomide (ZGR) for untre…

• CLINICAL_TRIALS other · 2025-12-23
  Clinical Trial Update: Epcoritamab and Rituximab for First-line Follicular Lymphoma [Phase 2]

  A Phase 2 clinical trial evaluating epcoritamab in combination with rituximab as first-line therapy for follicular lymphoma is currently rec…

• CLINICAL_TRIALS research · 2025-12-22
  Clinical Trial Update: A Study to Evaluate the Safety and Clinical Activity of GF- CART01 (CD20/19 CAR T Cell) in Subjects With Relapsed or Refractory B-Cell Hematological Malignancies [Phase 1]

  This clinical trial update describes a Phase 1 study of GF-CART01, a CD20/CD19 CAR T cell therapy, evaluating safety and early activity in a…

• EMA approval · 2025-12-18
  EMA Authorised: Breyanzi (lisocabtagene maraleucel) — Bristol-Myers Squibb Pharma EEIG

  The EMA authorised Breyanzi (lisocabtagene maraleucel) for additional lymphomas, including diffuse large B-cell lymphoma and follicular lymp…

• CLINICAL_TRIALS research · 2025-12-18
  Clinical Trial Update: Long-term Study to Evaluate Safety and Persistence of GF-CART01

  This clinical trial update describes a long-term safety and persistence study of GF-CART01, with enrollment not yet starting.

• CLINICAL_TRIALS trial_result · 2025-12-17
  Clinical Trial Update: Cytokine-Treated Veto Cells in Treating Patients With Hematologic Malignancies Following Stem Cell Transplant [Phase 1, Phase 2]

  Phase 1/2 clinical trial evaluating cytokine-treated veto cells as an adoptive therapy after stem cell transplantation for various hematolog…

• CLINICAL_TRIALS trial_result · 2025-12-15
  Clinical Trial Update: Mosunetuzumab and Polatuzumab Vedotin for Untreated Follicular Lymphoma [Phase 2]

  Phase 2 trial evaluating the combination of mosunetuzumab and polatuzumab vedotin as frontline therapy for untreated follicular lymphoma; th…

• CLINICAL_TRIALS research · 2025-12-10
  Clinical Trial Update: AS-1763 in Patients With Previously Treated CLL/SLL or Non-Hodgkin Lymphoma [Phase 1]

  An ongoing Phase 1 clinical trial update for AS-1763 in adults with previously treated B-cell malignancies, including chronic lymphocytic le…

• CLINICAL_TRIALS trial_result · 2025-12-10
  Clinical Trial Update: Lenalidomide and Epcoritamab for the Treatment of Previously Untreated Follicular Lymphoma [Phase 2]

  A Phase 2 trial of lenalidomide plus epcoritamab for previously untreated follicular lymphoma is currently suspended.