Focal Segmental Glomerulosclerosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2021-09-16Clinical Trial Update: Dose-Exploration Evaluating the Efficacy and Safety of Voclosporin in Subjects With Focal Segmental Glomerulosclerosis [Phase 2]
Phase 2 dose-exploration trial evaluating voclosporin for focal segmental glomerulosclerosis was terminated; results posted.
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CLINICAL_TRIALS withdrawal · 2021-08-30Clinical Trial Update: Acthar for Treatment of Post-transplant FSGS [Phase 4]
Phase 4 trial of Acthar for post-transplant focal segmental glomerulosclerosis was withdrawn.
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CLINICAL_TRIALS trial_result · 2021-07-27Clinical Trial Update: Randomized, Double-Blind, Safety and Efficacy Study of RE-021 (Sparsentan) in Focal Segmental Glomerulosclerosis [Phase 2]
A Phase 2 randomized, double-blind study evaluating sparsentan (RE-021) for safety and efficacy in focal segmental glomerulosclerosis has co…
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CLINICAL_TRIALS trial_result · 2021-03-05Clinical Trial Update: Pilot Study to Evaluate the Safety and Efficacy of Abatacept in Adults and Children 6 Years and Older With Excessive Loss of Protein in the Urine Due to Either Focal Segmental Glomerulosclerosis (FSGS) or Minimal Change Disease (MCD) [Phase 2]
Phase 2 pilot study evaluating abatacept for safety and efficacy in adults and children 6+ with nephrotic syndrome due to FSGS or minimal ch…
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CLINICAL_TRIALS trial_result · 2020-08-03Clinical Trial Update: FIRSTx - A Study of Oral CXA-10 in Primary Focal Segmental Glomerulosclerosis (FSGS) [Phase 2]
Phase 2 clinical trial update for CXA-10 in primary focal segmental glomerulosclerosis has been completed.
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CLINICAL_TRIALS trial_result · 2020-02-10Clinical Trial Update: A Pilot Study to Assess the Efficacy of Rituximab Therapy in Treatment Resistant FSGS [Phase 2]
Phase 2 pilot trial assessing rituximab for treatment-resistant focal segmental glomerulosclerosis has completed with posted results.
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CLINICAL_TRIALS trial_result · 2018-09-20Clinical Trial Update: Rituximab to Prevent Recurrence of Proteinuria [Phase 3]
Phase 3 trial update on rituximab to prevent recurrence of proteinuria in FSGS; the study was terminated with results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-08-27Clinical Trial Update: Efficacy of Rituximab in Comparison to Continued Corticosteroid Treatment in Idiopathic Nephrotic Syndrome [Phase 3]
A Phase 3 trial compares rituximab to continued corticosteroid treatment in idiopathic nephrotic syndrome, including minimal change disease …
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CLINICAL_TRIALS trial_result · 2018-01-16Clinical Trial Update: Treating to Reduce Albuminuria and Normalize Hemodynamic Function in Focal ScLerosis With dApagliflozin Trial Effects [Phase 4]
Phase 4 trial investigating dApagliflozin for reducing albuminuria and normalizing hemodynamic function in focal segmental glomerulosclerosi…
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CLINICAL_TRIALS research · 2017-06-20Clinical Trial Update: Valproic Acid for Idiopathic Nephrotic Syndrome [Phase 2, Phase 3]
Clinical trial update on valproic acid for idiopathic nephrotic syndrome, with Phase 2 and Phase 3, including mention of focal segmental glo…
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CLINICAL_TRIALS trial_result · 2017-06-12Clinical Trial Update: A Phase II, Repeat Dose, Proof of Mechanism Study of Losmapimod to Reduce Proteinuria in Patients With Focal Segmental Glomerulosclerosis (FSGS) [Phase 2]
This report covers results from a Phase II repeat-dose study of losmapimod in patients with focal segmental glomerulosclerosis to assess its…
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CLINICAL_TRIALS trial_result · 2017-04-24Clinical Trial Update: A Prospective Controlled Study of Serum suPAR in the CsA-treated FSGS Patients
This clinical trial update describes a prospective controlled study evaluating serum suPAR levels in CsA-treated patients with focal segment…
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CLINICAL_TRIALS trial_result · 2017-03-27Clinical Trial Update: The Efficacy and Safety of Tacrolimus in Treated Refractory Focal Segmental Glomerulosclerosis [NA]
A clinical trial evaluating tacrolimus for treated refractory focal segmental glomerulosclerosis has been terminated. The update notes the t…
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CLINICAL_TRIALS trial_result · 2016-07-11Clinical Trial Update: Novel Therapies for Resistant FSGS (FONTII): Phase II Clinical Trial [Phase 2]
Phase II clinical trial update for novel therapies targeting resistant focal segmental glomerulosclerosis (FSGS) under FONTII, with results …
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CLINICAL_TRIALS trial_result · 2016-02-10Clinical Trial Update: Permeability Factor in Focal Segmental Glomerulosclerosis [Phase 1, Phase 2]
Phase 1 and Phase 2 studies evaluated a permeability factor in focal segmental glomerulosclerosis. The trial results were posted in 2016 and…
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CLINICAL_TRIALS trial_result · 2015-12-04Clinical Trial Update: Allogenic AD-MSC Transplantation in Idiopathic Nephrotic Syndrome (Focal Segmental Glomerulosclerosis) [Phase 1]
This clinical trial update describes an early-phase study of allogeneic adipose-derived mesenchymal stem cell transplantation for idiopathic…
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CLINICAL_TRIALS trial_result · 2015-09-10Clinical Trial Update: Effect of Oral Galactose on Focal Segmental Glomerulosclerosis (FSGS) Permeability Factor [Phase 1]
A Phase 1 clinical trial evaluating oral galactose for the FSGS permeability factor has been terminated. The study, sponsored by Northwell H…
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CLINICAL_TRIALS withdrawal · 2015-09-07Clinical Trial Update: Effect of Galactose on Permeblity Factor in Patients With FSGS and CKD Stage 5 [Phase 1]
A Phase 1 trial investigating the effect of galactose on a permeability factor in patients with Focal Segmental Glomerulosclerosis and Chron…
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CLINICAL_TRIALS trial_result · 2015-08-26Clinical Trial Update: A Study of Fresolimumab in Patients With Steroid-Resistant Primary Focal Segmental Glomerulosclerosis (FSGS) [Phase 2]
Phase 2 clinical trial update indicating completion of a study evaluating Fresolimumab in patients with steroid-resistant primary focal segm…
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CLINICAL_TRIALS trial_result · 2015-05-27Clinical Trial Update: Regional Citrate Anticoagulation in Plasma Exchange Treatment [NA]
This record notes completion of a clinical trial evaluating regional citrate anticoagulation during plasma exchange for treatment of Focal s…
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CLINICAL_TRIALS trial_result · 2014-09-15Clinical Trial Update: Oral Galactose in Children With Steroid Resistant Nephrotic Syndrome [NA]
A completed clinical trial evaluated oral galactose in children with steroid-resistant nephrotic syndrome, including focal segmental glomeru…
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CLINICAL_TRIALS trial_result · 2014-09-01Clinical Trial Update: Idiopathic Focal Segmental Glomerulosclerosis (FSGS) and Treatment With ACTH [Phase 4]
This Phase 4 trial update reports results from using adrenocorticotropic hormone (ACTH) to treat idiopathic focal segmental glomeruloscleros…
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CLINICAL_TRIALS trial_result · 2014-05-15Clinical Trial Update: Aldosterone Breakthrough During Diovan, Tekturna, and Combination Therapy in Patients With Proteinuric Kidney Disease [Phase 4]
Phase 4 trial evaluating aldosterone breakthrough during Diovan, Tekturna, and combination therapy in proteinuric kidney disease was termina…
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CLINICAL_TRIALS trial_result · 2014-03-19Clinical Trial Update: Safety Study of GC1008 in Patients With Focal Segmental Glomerulosclerosis (FSGS) of Single Doses of GC1008 in Patients With Treatment Resistant Idiopathic FSGS [Phase 1]
The document reports completion of a Phase 1 safety study of GC1008 (fresolimumab) in patients with treatment-resistant idiopathic focal seg…
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CLINICAL_TRIALS trial_result · 2013-10-23Clinical Trial Update: Mycophenolate Mofetil in Membranous Nephropathy and Focal Segmental [Phase 3]
Phase 3 trial update showing completion status for mycophenolate mofetil in membranous nephropathy and focal segmental glomerulosclerosis.