Essential Thrombocythemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2019-12-03Clinical Trial Update: Phase IIA Study of the HDAC Inhibitor ITF2357 in Patients With JAK-2 V617F Positive Chronic Myeloproliferative Diseases [Phase 2]
Phase IIa study of HDAC inhibitor ITF2357 in JAK-2 V617F positive myeloproliferative diseases has completed with posted results.
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CLINICAL_TRIALS trial_result · 2019-05-15Clinical Trial Update: Sympathicomimetic Agonist in Patients With Myeloproliferative Neoplasms With JAK2-mutation [Phase 2]
Phase 2 clinical trial update evaluating a sympathicomimetic agonist in patients with myeloproliferative neoplasms carrying JAK2 mutations, …
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CLINICAL_TRIALS trial_result · 2018-10-16Clinical Trial Update: Study of LY573636-sodium in Essential Thrombocythemia and Acute Myeloid Leukemia [Phase 1]
Phase 1 study of LY573636-sodium in Acute Myeloid Leukemia and Essential Thrombocythemia completed with results posted.
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CLINICAL_TRIALS trial_result · 2018-07-24Clinical Trial Update: Randomized Trial of Pegylated Interferon Alfa-2a Versus Hydroxyurea in Polycythemia Vera (PV) and Essential Thrombocythemia (ET) [Phase 3]
A Phase 3 randomized trial comparing pegylated interferon alfa-2a to hydroxyurea in high-risk polycythemia vera and high-risk essential thro…
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CLINICAL_TRIALS trial_result · 2018-04-17Clinical Trial Update: A Study in Myeloproliferative Disorders [Phase 1]
Phase 1 study in myeloproliferative neoplasms has completed, evaluating patients with essential thrombocythemia, polycythemia vera, and prim…
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CLINICAL_TRIALS trial_result · 2018-01-24Clinical Trial Update: A Study of Anagrelide and Hydroxyurea in High-Risk Essential Thrombocythemia Patients [Phase 4]
Phase 4 trial update for anagrelide and hydroxyurea in high-risk essential thrombocythemia completed with results posted.
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CLINICAL_TRIALS trial_result · 2017-04-24Clinical Trial Update: Study to Assess the Safety of AZD1480 in Patients With Myeloproliferative Diseases [Phase 1]
A Phase 1 trial evaluating the safety of AZD1480 in adults with myeloproliferative diseases has completed, with results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-04-12Clinical Trial Update: Study of LY2784544 Testing Alternative Dosing in Participants With Myeloproliferative Neoplasms [Phase 1]
Phase 1 study of LY2784544 testing alternative dosing in patients with myeloproliferative neoplasms, including polycythemia vera, essential …
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CLINICAL_TRIALS trial_result · 2017-03-29Clinical Trial Update: Biological Therapy in Treating Patients With Advanced Myelodysplastic Syndrome, Acute or Chronic Myeloid Leukemia, or Acute Lymphoblastic Leukemia Who Are Undergoing Stem Cell Transplantation [Phase 1, Phase 2]
A Phase 1/2 clinical trial update reports completion of a study evaluating an investigational biological therapy in adults with advanced mye…
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CLINICAL_TRIALS trial_result · 2017-01-18Clinical Trial Update: Primary Thrombocythaemia 1 Trial [NA]
This is a completed status update for the Primary Thrombocythemia 1 clinical trial conducted by the University of Cambridge.
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CLINICAL_TRIALS trial_result · 2017-01-11Clinical Trial Update: Pegylated Interferon Alfa-2a Salvage Therapy in High Risk Polycythemia Vera (PV) or Essential Thrombocythemia (ET) [Phase 2]
A Phase 2 trial evaluating pegylated interferon alfa-2a as salvage therapy in high-risk polycythemia vera or high-risk essential thrombocyth…
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CLINICAL_TRIALS trial_result · 2016-06-15Clinical Trial Update: Retrospective Data Collection of Routine Use With Spectra Optia® for Platelet Depletions
A retrospective data collection evaluating routine use of the Spectra Optia device for platelet depletions.
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CLINICAL_TRIALS trial_result · 2016-06-08Clinical Trial Update: Long-term Safety of SPD422 in Japanese Adults With Essential Thrombocythaemia [Phase 3]
Phase 3 trial update reporting long-term safety of SPD422 in Japanese adults with essential thrombocythemia.
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CLINICAL_TRIALS trial_result · 2016-05-26Clinical Trial Update: Anagrelide Retard vs. Placebo: Efficacy and Safety in "At-risk" Patients With Essential Thrombocythaemia [Phase 3]
A Phase 3 trial comparing anagrelide retard to placebo in at-risk patients with essential thrombocythemia reports efficacy and safety result…
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CLINICAL_TRIALS trial_result · 2016-05-23Clinical Trial Update: HSP90 Inhibitor, AUY922, in Patients With Primary Myelofibrosis (PMF), Post-Polycythemia Vera Myelofibrosis (Post-PV MF), Post-Essential Thrombocythemia Myelofibrosis (Post-ET MF), and Refractory PV/ET [Phase 2]
Phase 2 trial of the HSP90 inhibitor AUY922 in myeloproliferative neoplasms including primary myelofibrosis and MF after PV/ET was terminate…
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CLINICAL_TRIALS trial_result · 2016-01-26Clinical Trial Update: Open Label Study to Evaluate the Activity of Imetelstat in Patients With Essential Thrombocythemia or Polycythemia Vera [Phase 2]
An open-label Phase 2 trial evaluating imetelstat in essential thrombocythemia or polycythemia vera has completed.
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CLINICAL_TRIALS trial_result · 2015-07-29Clinical Trial Update: Anagrelide Retard in Essential Thrombocythemia [Phase 3]
Phase 3 trial update for Anagrelide Retard in essential thrombocythemia; the study status is completed.
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CLINICAL_TRIALS trial_result · 2014-08-28Clinical Trial Update: Anti-TGF-beta Therapy in Patients With Myelofibrosis [Phase 1]
Phase 1 trial evaluating an anti-TGF-beta therapy in myelofibrosis was terminated; results were posted in 2014.
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CLINICAL_TRIALS trial_result · 2014-07-29Clinical Trial Update: Exploratory Multi-centre Trial In Patients With ET Treated With XAGRID®
Exploratory multi-centre trial in essential thrombocythemia patients treated with XAGRID®. Completed with results posted in 2014.
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CLINICAL_TRIALS trial_result · 2014-05-21Clinical Trial Update: 3-AP and Fludarabine in Treating Patients With Myeloproliferative Disorders, Chronic Myelomonocytic Leukemia, or Accelerated Phase or Blastic Phase Chronic Myelogenous Leukemia [Phase 2]
Phase 2 trial evaluating the combination of Triapine (3-AP) and fludarabine in various myeloproliferative disorders and advanced phases of c…
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CLINICAL_TRIALS trial_result · 2014-02-25Clinical Trial Update: Imatinib Mesylate in Treating Patients With Myelofibrosis [Phase 2]
Phase 2 clinical trial evaluating Imatinib Mesylate in patients with myelofibrosis has completed. The study also addresses related myeloprol…
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CLINICAL_TRIALS trial_result · 2013-09-26Clinical Trial Update: Lenalidomide and Prednisone in Treating Patients With Myelofibrosis [Phase 2]
This Phase 2 trial evaluated lenalidomide in combination with prednisone for patients with myelofibrosis and related myeloproliferative neop…
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CLINICAL_TRIALS trial_result · 2013-09-25Clinical Trial Update: Effect of SPD422 on Platelet Lowering and Safety in Japanese Adults With At Risk Essential Thrombocythaemia [Phase 3]
Phase 3 clinical trial exploring SPD422 for reducing platelets in Japanese adults at risk of essential thrombocythemia; study completed with…
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CLINICAL_TRIALS trial_result · 2013-09-25Clinical Trial Update: French Observational Xagrid (FOX) Study In Adult Patients With Essential Thrombocythemia
Observational study in adults with essential thrombocythemia completed; results posted in 2013.
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CLINICAL_TRIALS trial_result · 2013-06-17Clinical Trial Update: Plasma Vitamin and Homocysteine Levels and Thrombosis in Patients With Ph-negative MPNs
This clinical trial update reports on plasma vitamin and homocysteine levels and thrombosis in patients with Philadelphia-negative myeloprol…