Essential Hypertension
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2015-10-21Clinical Trial Update: A Long-term (12 Months) Safety, Tolerability and Efficacy Study of LCZ696 in Patients With Essential Hypertension [Phase 2]
Long-term (12-month) Phase 2 study evaluating safety, tolerability and efficacy of LCZ696 (sacubitril/valsartan) in essential hypertension. …
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CLINICAL_TRIALS trial_result · 2015-10-19Clinical Trial Update: To Evaluate the Drug-drug Interaction Between Telmisartan and Atorvastatin in Healthy Male Volunteers [Phase 1]
Phase 1 clinical trial update reporting completion of a study evaluating the drug-drug interaction between telmisartan and atorvastatin in h…
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CLINICAL_TRIALS trial_result · 2015-10-02Clinical Trial Update: Comparison of Ultrafast Echo With Echotracking
Completed clinical trial comparing ultrafast echo imaging with echotracking in patients with essential hypertension and in healthy volunteer…
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CLINICAL_TRIALS trial_result · 2015-09-23Clinical Trial Update: Efficacy and Safety of HL-040XC in Essential Hypertension and Hyperlipidemia [Phase 3]
Phase 3 clinical trial evaluating the efficacy and safety of HL-040XC for essential hypertension and hyperlipidemia has completed; results a…
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CLINICAL_TRIALS trial_result · 2015-09-04Clinical Trial Update: Efficacy and Safety of LCZ696 in Comparison to Olmesartan in Asian Patients With Essential Hypertension [Phase 3]
A Phase 3 trial compared LCZ696 (sacubitril/valsartan) with olmesartan in Asian patients with essential hypertension to assess efficacy and …
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CLINICAL_TRIALS trial_result · 2015-08-25Clinical Trial Update: Perindopril Amlodipine for the Treatment of Hypertension [Phase 3]
This Phase 3 trial evaluating the fixed-dose combination of perindopril and amlodipine for essential hypertension has completed, with result…
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CLINICAL_TRIALS withdrawal · 2015-08-25Clinical Trial Update: Microvascular Function in Primary Aldosteronism
The trial NCT02096939 evaluating microvascular function in primary aldosteronism and essential hypertension has been withdrawn.
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CLINICAL_TRIALS trial_result · 2015-08-20Clinical Trial Update: The Effects of Amiloride and Spironolactone on Renophysiological and Cardiovascular Variables [NA]
Clinical trial evaluated the effects of amiloride and spironolactone on renal physiological and cardiovascular variables in essential hypert…
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CLINICAL_TRIALS trial_result · 2015-08-19Clinical Trial Update: Efficacy and Safety of LCZ696 Compared to Placebo in Patients With Essential Hypertension [Phase 2]
Phase 2 trial comparing Entresto (sacubitril/valsartan) to placebo in essential hypertension evaluated efficacy and safety.
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CLINICAL_TRIALS trial_result · 2015-08-18Clinical Trial Update: Efficacy and Safety of LCZ696 200 mg + Amlodipine 5 mg in Comparison With Amlodipine 5 mg in Hypertensive Patients Not Responding to Amlodipine [Phase 3]
Phase 3 trial evaluating the efficacy and safety of sacubitril/valsartan (LCZ696) 200 mg added to amlodipine 5 mg versus amlodipine 5 mg alo…
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CLINICAL_TRIALS trial_result · 2015-08-18Clinical Trial Update: Efficacy and Safety of LCZ696 in Comparison to Olmesartan in Elderly Patients With Essential Hypertension [Phase 3]
A Phase 3 trial comparing Entresto (sacubitril/valsartan) to olmesartan in elderly patients with essential hypertension to assess efficacy a…
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CLINICAL_TRIALS trial_result · 2015-08-17Clinical Trial Update: Open-Label Long-Term Safety and Efficacy Study of Fixed Dose Combination of Nifedipine Gastrointestinal Therapeutic System and Candesartan Cilexetil in Subjects With Moderate to Severe Essential Hypertension [Phase 3]
Open-label Phase 3 study evaluating the long-term safety and efficacy of a fixed-dose combination of Nifedipine GITS and Candesartan Cilexet…
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CLINICAL_TRIALS trial_result · 2015-08-06Clinical Trial Update: Efficacy and Safety of LCZ696 in Comparison to Olmesartan in Japanese Patients With Essential Hypertension [Phase 3]
Phase 3 trial comparing LCZ696 (sacubitril/valsartan) to olmesartan in Japanese patients with essential hypertension. Results and safety dat…
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CLINICAL_TRIALS trial_result · 2015-07-27Clinical Trial Update: Fimasartan/Amlodipine Combination Phase III [Phase 3]
Phase III trial of the fixed-dose combination fimasartan/amlodipine for essential hypertension has completed (status COMPLETED). No efficacy…
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CLINICAL_TRIALS trial_result · 2015-06-09Clinical Trial Update: Efficacy and Safety of Fimasartan Alone or Combined With HCTZ in Mexican Patients With Essential Hypertension [Phase 3]
Phase 3 trial evaluating the efficacy and safety of fimasartan alone or in combination with hydrochlorothiazide in Mexican patients with ess…
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CLINICAL_TRIALS trial_result · 2015-06-09Clinical Trial Update: The Renin-Angiotensin System in Essential Hypertension [NA]
A clinical trial on the renin-angiotensin system in essential hypertension has been terminated.
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CLINICAL_TRIALS research · 2015-05-22Clinical Trial Update: Evaluation of Stendo Pulsating Suit on Microcirculation and Central Blood Pressure in Essential Hypertension Patients [NA]
This clinical trial evaluates the Stendo Pulsating Suit's impact on microcirculation and central blood pressure in adults with essential hyp…
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FDA approval · 2015-04-28FDA Approved: LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE — Supplemental Application (Jubilant Cadista Pharmaceuticals Inc.)
FDA approved a supplemental application for Jubilant Cadista's generic losartan potassium and hydrochlorothiazide tablet, a combination anti…
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CLINICAL_TRIALS trial_result · 2015-04-02Clinical Trial Update: Efficacy and Safety of Azilsartan Compared to Olmesartan Medoxomil in Chinese Participants With Grade I or II Essential Hypertension [Phase 3]
A Phase 3 trial in Chinese adults with essential hypertension compares azilsartan to olmesartan medoxomil to assess efficacy and safety outc…
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CLINICAL_TRIALS trial_result · 2015-03-30Clinical Trial Update: A Dose Selection Trial of CKD-330 in Patients With Essential Hypertension [Phase 2]
A Phase 2 dose-selection trial of CKD-330 in adults with essential hypertension; the study is sponsored by Chong Kun Dang Pharmaceutical and…
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CLINICAL_TRIALS trial_result · 2015-02-06Clinical Trial Update: Efficacy Study of Nifedipine Controlled-Release Tablets (Xin Ran) to Treat Early Morning Blood Pressure and Central Arterial Pressure [Phase 4]
Phase 4 efficacy study update for Xin Ran (nifedipine controlled-release tablets) evaluating early morning blood pressure and central arteri…
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CLINICAL_TRIALS trial_result · 2015-02-05Clinical Trial Update: Efficacy Study of Nifedipine Controlled-Release Tablets (Xin Ran) to Treat Mild to Moderate Essential Hypertension [Phase 4]
Phase 4 efficacy study of nifedipine controlled-release tablets (Xin Ran) for essential hypertension has completed; the snippet does not rep…
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CLINICAL_TRIALS trial_result · 2014-11-18Clinical Trial Update: GRK4 Polymorphisms Blood Pressure Response to Candesartan [Phase 4]
Phase 4 clinical trial update investigating whether GRK4 polymorphisms influence blood pressure response to candesartan in patients with ess…
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FDA approval · 2014-10-30FDA Approved: BYSTOLIC — Supplemental Application (Allergan, Inc.)
The FDA approved Allergan's supplemental application for BYSTOLIC (nebivolol hydrochloride).
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CLINICAL_TRIALS trial_result · 2014-09-17Clinical Trial Update: Effectiveness of MICARDIS® (Telmisartan) on Blood Pressure Control and Quality of Live in Patients With Essential Hypertension [Phase 4]
This Phase 4 trial assesses the effectiveness of MICARDIS (telmisartan) for blood pressure control in adults with essential hypertension, an…