Essential Hypertension
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CLINICAL_TRIALS trial_result · 2024-05-07Clinical Trial Update: Study to Evaluate the Efficacy and Safety of SPH3127 In Patients With Mild-moderate Essential Hypertension [Phase 3]
This entry notes the completion of a Phase 3 trial evaluating SPH3127 for mild-to-moderate essential hypertension, focusing on efficacy and …
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CLINICAL_TRIALS trial_result · 2024-05-02Clinical Trial Update: Effects of Valsartan vs Amlodipine and Low BP on Kidney Outcomes in Essential Hypertension [Phase 3]
Phase 3 trial comparing valsartan to amlodipine for blood pressure management and kidney outcomes in adults with essential hypertension; the…
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CLINICAL_TRIALS trial_result · 2024-04-05Clinical Trial Update: Clinical Trial to Evaluate the Efficacy and Safety of D064 and D702 Combination Therapy Versus D064 or D702 Monotherapy [Phase 3]
Phase 3 trial evaluating D064 and D702 combination therapy versus monotherapy in essential hypertension has completed.
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CLINICAL_TRIALS trial_result · 2024-04-05Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of AD-209 [Phase 2]
Phase 2 clinical trial assessing efficacy and safety of AD-209 for hypertension (essential hypertension) has completed.
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CLINICAL_TRIALS trial_result · 2024-02-28Clinical Trial Update: Peripheral Vascular Effects of Sulfhydryl-containing Antihypertensive Pharmacotherapy on Microvessels in Humans [Phase 1, Phase 2]
Phase 1/2 trial investigating sulfhydryl-containing antihypertensive therapy and its microvascular effects in humans; the study status is te…
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CLINICAL_TRIALS trial_result · 2024-01-19Clinical Trial Update: Evaluate the Efficacy and Safety of SPC1001 and Monotherapy in Patients With Essential Hypertension [Phase 2]
Phase 2 trial update evaluating SPC1001 with monotherapy for essential hypertension; study completed.
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CLINICAL_TRIALS trial_result · 2023-11-21Clinical Trial Update: NW Roselle in Grade 1 Essential Hypertension: Phase III Clinical Trial [Phase 3]
Phase III clinical trial update for NW Roselle in essential hypertension; status unknown.
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FDA approval · 2023-10-23FDA Approved: HYDROCHLOROTHIAZIDE — Supplemental Application (Oxford Pharmaceuticals, LLC)
FDA approved a supplemental application for hydrochlorothiazide from Oxford Pharmaceuticals, LLC. This action pertains to regulatory approva…
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FDA approval · 2023-09-14FDA Approved: IRBESARTAN AND HYDROCHLOROTHIAZIDE — Supplemental Application (Aurobindo Pharma Limited)
The FDA approved a supplemental application for the irbesartan and hydrochlorothiazide combination from Aurobindo Pharma Limited.
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FDA approval · 2023-08-25FDA Approved: NEBIVOLOL HYDROCHLORIDE — Supplemental Application (Unichem Pharmaceuticals (USA), Inc.)
FDA approved a supplemental application for Nebivolol hydrochloride (Unichem Pharmaceuticals USA) for a generic product. Nebivolol hydrochlo…
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CLINICAL_TRIALS trial_result · 2023-08-18Clinical Trial Update: Clinical Efficacy and Safety Evaluation of Irbesartan and Amlodipine Combined Therapy in Essential Hypertension Patients [Phase 3]
Phase 3 clinical trial evaluating the efficacy and safety of combined irbesartan and amlodipine therapy in essential hypertension has comple…
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CLINICAL_TRIALS trial_result · 2023-08-18Clinical Trial Update: Clinical Efficacy and Safety Evaluation of Irbesartan High and Amlodipine Combined Therapy in Essential Hypertension Patients [Phase 3]
Phase 3 trial evaluating the efficacy and safety of high-dose irbesartan combined with amlodipine for essential hypertension has been comple…
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FDA approval · 2023-06-28FDA Approved: SPIRONOLACTONE — Supplemental Application (Amneal Pharmaceuticals LLC)
The FDA approved a supplemental application for Spironolactone from Amneal Pharmaceuticals LLC.
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CLINICAL_TRIALS trial_result · 2023-05-06Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Amlodipine Besylate and Candesartan Cilexetil in Essential Hypertension Patient Who Are Not Adequately Controlled With Candesartan Cilexetil Monotherapy [Phase 3]
Phase 3 trial evaluating the combination of amlodipine besylate and candesartan cilexetil in essential hypertension inadequately controlled …
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CLINICAL_TRIALS trial_result · 2023-05-06Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Amlodipine Besylate and Candesartan Cilexetil in Essential Hypertension Patient Who Are Not Adequately Controlled With Amlodipine Besylate Monotherapy [Phase 3]
Phase 3 trial evaluating add-on amlodipine besylate with candesartan cilexetil in patients with essential hypertension not adequately contro…
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CLINICAL_TRIALS trial_result · 2023-05-06Clinical Trial Update: A Clinical Trial to Evaluate the Blood Pressure Control of Telmisartan or Losartan in Essential Hypertensive Patients With Metabolic Syndrome [Phase 4]
A Phase 4 clinical trial evaluating blood pressure control with telmisartan or losartan in patients with essential hypertension and metaboli…
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CLINICAL_TRIALS trial_result · 2023-02-01Clinical Trial Update: Evaluation of Efficacy and Safety of ATB-1011+ATB-1012 Co-administration for Essential Hypertension and Type II Diabetes [Phase 3]
Phase 3 trial evaluating the efficacy and safety of co-administration of ATB-1011 with ATB-1012 for essential hypertension and type 2 diabet…
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CLINICAL_TRIALS trial_result · 2023-02-01Clinical Trial Update: Study MIPAE - Melatonin and Essential Arterial Hypertension [Phase 2]
Phase 2 trial update for MIPAE evaluating melatonin in essential hypertension; current status unknown.
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CLINICAL_TRIALS trial_result · 2022-12-07Clinical Trial Update: Study on Human Mass Balance of SPH3127 Tablets [Phase 1, Phase 2]
Phase 1/2 study evaluating human mass balance of SPH3127 tablets for hypertension has completed.
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CLINICAL_TRIALS trial_result · 2022-11-28Clinical Trial Update: Clinical Trial to Evaluate the Efficacy and Safety of D064 and D701 Combination Therapy [Phase 3]
A Phase 3 clinical trial update evaluating the combination therapy of D064 and D701 for essential hypertension is ongoing with unknown statu…
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CLINICAL_TRIALS trial_result · 2022-08-18Clinical Trial Update: Phase III Study to Evaluate the Efficacy and Safety of AGSAVI in Patients With Essential Hypertension Inadequately Controlled With AGLS [Phase 3]
Phase III study evaluating efficacy and safety of AGSAVI in patients with essential hypertension inadequately controlled with AGLS; status i…
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CLINICAL_TRIALS trial_result · 2022-07-14Clinical Trial Update: A Phase 2 Study to Assess Dose-response Relationship of HCP1803 in Patients With Essential Hypertension [Phase 2]
Phase 2 study assessing dose-response of HCP1803 in patients with essential hypertension has completed.
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CLINICAL_TRIALS trial_result · 2022-06-30Clinical Trial Update: Phase 2 Study to Evaluate the Efficacy and Safety of Irbesartan and Amlodipine Combined or Alone in Patients With Essential Hypetension [Phase 2]
Phase 2 study assessing efficacy and safety of irbesartan and amlodipine combined or alone in essential hypertension has completed.
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CLINICAL_TRIALS trial_result · 2021-11-15Clinical Trial Update: Safety and Efficacy of SPH3127 on Treating Mild-moderate Essential Hypertension Patients [Phase 2]
Phase 2 trial update on SPH3127 for mild-to-moderate essential hypertension evaluating safety and efficacy.
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CLINICAL_TRIALS trial_result · 2021-09-21Clinical Trial Update: An Integrated Assessment of the Safety and Effectiveness of Bexagliflozin for the Management of Essential Hypertension [Phase 2, Phase 3]
A trial update evaluating the safety and effectiveness of bexagliflozin for essential hypertension across Phase 2 and Phase 3 stages; study …