Essential Hypertension
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2014-01-14Clinical Trial Update: Efficacy and Safety of Carvedilol SR Versus Carvedilol IR in Patients With Essential Hypertension [Phase 3]
A Phase 3 trial comparing carvedilol sustained-release to carvedilol immediate-release in adults with essential hypertension to evaluate com…
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CLINICAL_TRIALS trial_result · 2014-01-06Clinical Trial Update: A Long-term Study of the Safety of MK-0954A in Patients With Essential Hypertension (MK-0954A-351) [Phase 3]
A Phase 3 long-term safety study of MK-0954A in patients with essential hypertension completed, with results posted in 2014.
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CLINICAL_TRIALS trial_result · 2013-12-06Clinical Trial Update: Aliskiren in Combination With Amlodipine in Hypertensive Patients Not Responding to Angiotensin Receptor Blocker (ARB) Plus Amlodipine [Phase 3]
This Phase 3 trial update reports on evaluating aliskiren in combination with amlodipine for hypertensive patients not responding to ARB plu…
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CLINICAL_TRIALS trial_result · 2013-11-11Clinical Trial Update: Study to Evaluate the Trough and Peak Effect of Once Daily Telmisartan 80 mg/Hydrochlorothiazide 12.5 mg (Micardis Plus) by Ambulatory Blood Pressure Monitoring (ABPM) in Patients With Mild to Moderate Essential Hypertension [Phase 3]
Phase 3 study evaluating the trough and peak effect of once-daily telmisartan 80 mg with hydrochlorothiazide 12.5 mg (Micardis Plus) using a…
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CLINICAL_TRIALS trial_result · 2013-11-05Clinical Trial Update: Combination of Telmisartan 40 mg Plus Hydrochlorothiazide (HCTZ) 12.5 mg vs. Telmisartan 40 mg Alone in Patients With Essential Hypertension Who Fail to Respond Adequately to Telmisartan Monotherapy [Phase 3]
Phase 3 trial comparing the combination of telmisartan and hydrochlorothiazide against telmisartan alone in patients with essential hyperten…
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CLINICAL_TRIALS trial_result · 2013-10-08Clinical Trial Update: Efficacy of Amlodipine-Folic Acid Tablets on Reduction of Blood Pressure and Plasma Homocysteine [Phase 2, Phase 3]
Phase 2/3 clinical trial update examining whether amlodipine-folic acid tablets reduce blood pressure and plasma homocysteine in essential h…
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CLINICAL_TRIALS trial_result · 2013-08-01Clinical Trial Update: Study to Investigate the Effect of Atorvastatin on the Pharmacokinetic Properties of Telmisartan/S-amlodipine [Phase 1]
Phase 1 study evaluating whether atorvastatin affects the pharmacokinetics of Telmisartan/S-amlodipine in patients with essential hypertensi…
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CLINICAL_TRIALS trial_result · 2013-08-01Clinical Trial Update: Study to Investigate the Effect of Telmisartan/S-amlodipine on the Pharmacokinetic Properties of Atorvastatin. [Phase 1]
A Phase 1 trial evaluating whether telmisartan/S-amlodipine affects the pharmacokinetics of atorvastatin has completed.
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CLINICAL_TRIALS trial_result · 2013-07-16Clinical Trial Update: Study of the Product QGC001 as a Single Dose and Multiple Doses Administered Orally to Healthy Adult Subjects [Phase 1]
A Phase 1 trial of QGC001 evaluating single-dose and multiple-dose oral administration in healthy adults for essential hypertension has comp…
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CLINICAL_TRIALS trial_result · 2013-07-16Clinical Trial Update: Phase I Study in Healthy Male Subjects Comparing QGC001 to Placebo [Phase 1]
Phase I randomized, placebo-controlled study in healthy male volunteers to evaluate safety, tolerability, and pharmacokinetics of QGC001 com…
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CLINICAL_TRIALS trial_result · 2013-06-12Clinical Trial Update: Monotherapy Versus Dual Therapy for Initial Treatment for Hypertension [Phase 4]
Phase 4 clinical trial update comparing monotherapy versus dual therapy as initial treatment for hypertension; current status is unknown.
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CLINICAL_TRIALS trial_result · 2013-06-10Clinical Trial Update: The Prevalence of Sympathetic Overactivity in Primary Hypertensive Patients.
The clinical trial evaluating sympathetic overactivity in essential hypertension has completed.
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CLINICAL_TRIALS trial_result · 2013-05-14Clinical Trial Update: Effects of Combination Therapy With Alpha-1 Blocker (Bunazosin or Doxazosin) in the Treatment of Patients With Mild to Moderate Essential Hypertension [Phase 4]
Phase 4 clinical trial evaluating the effects of combining alpha-1 blockers Bunazosin or Doxazosin in patients with mild to moderate essenti…
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CLINICAL_TRIALS trial_result · 2013-05-08Clinical Trial Update: Efficacy of Amlodipine-folic Acid Tablets on Reduction of Blood Pressure and Plasma Homocysteine [Phase 2, Phase 3]
The trial evaluates the efficacy of an amlodipine–folic acid combination tablet for lowering blood pressure and plasma homocysteine in essen…
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CLINICAL_TRIALS trial_result · 2013-04-17Clinical Trial Update: Effectiveness of Eplerenone to Improve Target Organ Damage in Patients With Resistant Arterial Hypertension [Phase 3]
A Phase 3 trial evaluating eplerenone for reducing target organ damage in patients with resistant arterial hypertension has completed. The u…
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CLINICAL_TRIALS trial_result · 2013-02-18Clinical Trial Update: Motivational Interviewing [NA]
A clinical trial assessing motivational interviewing for essential hypertension has been terminated.
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CLINICAL_TRIALS trial_result · 2013-01-08Clinical Trial Update: Effects of Bisoprolol and Atenolol on Sympathetic Nervous Activity and Central Aortic Pressure in Patients With Essential Hypertension [Phase 4]
Phase 4 study evaluating the effects of bisoprolol and atenolol on sympathetic nervous activity and central aortic pressure in patients with…
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CLINICAL_TRIALS trial_result · 2013-01-04Clinical Trial Update: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Response of Vasomera (PB1046) Injection Following a Single Subcutaneous Dose in Subjects With Stage 1 or 2 Essential Hypertension [Phase 1]
Phase 1 study evaluating safety, tolerability, and pharmacokinetics/pharmacodynamics of a single subcutaneous dose of Vasomera (PB1046) in a…
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CLINICAL_TRIALS trial_result · 2012-11-12Clinical Trial Update: Safety and Tolerability of Azilsartan Medoxomil Plus Chlorthalidone Compared to Olmesartan Medoxomil Plus Hydrochlorothiazide in Participants With Essential Hypertension [Phase 3]
Phase 3 safety and tolerability comparison of azilsartan medoxomil with chlorthalidone versus olmesartan medoxomil with hydrochlorothiazide …
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CLINICAL_TRIALS trial_result · 2012-10-10Clinical Trial Update: Ramipril and Hydrochlorothiazide Alone and in Combination for the Treatment of Essential Hypertension [Phase 3]
A Phase 3 trial evaluating ramipril and hydrochlorothiazide alone and in combination for essential hypertension has completed.
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CLINICAL_TRIALS trial_result · 2012-08-28Clinical Trial Update: Effects of Spironolactone Combination Therapy on Proteinuria, Kidney Function, and Blood Pressure [Phase 2]
Phase 2 results from Tehran University of Medical Sciences evaluate spironolactone in combination therapy for reducing proteinuria, preservi…
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CLINICAL_TRIALS trial_result · 2012-08-21Clinical Trial Update: Safety, Tolerability, Pharmacodynamic Effects and Preliminary Evidence for Efficacy of the Anti-Hypertension Vaccine CYT006-AngQb [Phase 1, Phase 2]
Phase 1/2 trial update reporting safety and tolerability, pharmacodynamic effects and preliminary evidence of efficacy for the anti-hyperten…
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CLINICAL_TRIALS trial_result · 2012-08-15Clinical Trial Update: Inflammatory Response to Salt in Essential Hypertension [Phase 3]
A Phase 3 clinical trial evaluating the inflammatory response to salt in individuals with essential hypertension has completed.
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CLINICAL_TRIALS trial_result · 2012-08-13Clinical Trial Update: Effects of Angiotensin II Receptor Blocker Compared With Diuretics in High-risk Hypertensive Patients [Phase 4]
This report summarizes a Phase 4 clinical trial comparing an angiotensin II receptor blocker with a diuretic in high-risk patients with esse…
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CLINICAL_TRIALS trial_result · 2012-07-10Clinical Trial Update: L-Arginine Metabolism in Essential Hypertension [Phase 2, Phase 3]
The document reports completion of a Phase 2/Phase 3 clinical trial investigating L-Arginine metabolism in essential hypertension.