Esophageal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Statistical Analysis Plan for the SANO-trial: Neoadjuvant Chemoradiotherapy Followed by Surgery Versus Active Surveillance for Oesophageal Cancer [NA]
This document outlines the statistical analysis plan for the SANO-trial, which compares neoadjuvant chemoradiotherapy followed by surgery ve…
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CLINICAL_TRIALS other · 2024-09-19Clinical Trial Update: Efficacy and Safety of Penpulimab Combined With Anlotinib and Chemotherapy [Phase 2]
A Phase 2 clinical trial is evaluating Penpulimab in combination with Anlotinib and chemotherapy for esophageal cancer. The trial is current…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Study of Adebrelimab With Chemotherapy, Endoscopy and Sequential Chemoradiotherapy In Inoperable Esophageal Cancer [Phase 2]
Phase 2 clinical trial evaluating Adebrelimab with chemotherapy, endoscopy, and sequential chemoradiotherapy in esophageal squamous cell car…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Maintenance Chemotherapy With S-1, Locally Advanced Esophageal Cancer Receiving Definitive CCRT [Phase 2]
Phase 2 trial evaluating maintenance chemotherapy with S-1 for locally advanced unresectable esophageal cancer receiving definitive concurre…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Treatment Outcomes of Esophageal Cancer
A UCSF-sponsored clinical trial is recruiting to study treatment outcomes for esophageal cancer.
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CLINICAL_TRIALS trial_result · 2024-09-04Clinical Trial Update: ADP-A2M4CD8 in HLA-A2+ Subjects With MAGE-A4 Positive Esophageal or Esophagogastric Junction Cancers (SURPASS-2) [Phase 2]
Phase 2 SURPASS-2 trial evaluating ADP-A2M4CD8 in HLA-A2+ patients with MAGE-A4 positive esophageal or esophagogastric junction cancers was …
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CLINICAL_TRIALS trial_result · 2024-08-28Clinical Trial Update: Preoperative Chemotherapy vs. Chemoradiation in Esophageal / GEJ Adenocarcinoma [Phase 2, Phase 3]
This clinical trial update describes the completion of Phase 2 and Phase 3 trials comparing preoperative chemotherapy versus preoperative ch…
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CLINICAL_TRIALS trial_result · 2024-08-27Clinical Trial Update: Temporal Variation in Exhaled Volatile Organic Compounds in Esophageal Cancer Patients [NA]
A completed clinical trial from Benaroya Research Institute evaluating temporal variation in exhaled volatile organic compounds in patients …
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CLINICAL_TRIALS research · 2024-08-26Clinical Trial Update: The Study on the Mechanism of Radiotherapy-elicited Immune Response
A study at Fudan University is investigating how radiotherapy elicits an immune response in esophageal cancer and is currently recruiting pa…
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CLINICAL_TRIALS trial_result · 2024-08-26Clinical Trial Update: Trilaciclib Combined With Concurrent Chemoradiotherapy and Immunotherapy in the Treatment of Esophageal Cancer [Phase 2]
A Phase 2 clinical trial is evaluating trilaciclib in combination with concurrent chemoradiotherapy and immunotherapy for esophageal cancer;…
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CLINICAL_TRIALS research · 2024-08-26Clinical Trial Update: A Study of Bi-Ligand-Drug Conjugate CBP-1019 in Patients With Advanced Solid Tumors [Phase 1, Phase 2]
This clinical trial update reports on a Phase 1/2 study of CBP-1019, a bi-ligand-drug conjugate, in patients with advanced solid tumors incl…
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CLINICAL_TRIALS research · 2024-08-23Clinical Trial Update: Prehab for Lung and Esophageal Cancer [NA]
A clinical trial is recruiting to study prehabilitation (exercise before surgery) for patients with lung and esophageal cancer.
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CLINICAL_TRIALS research · 2024-08-21Clinical Trial Update: Erasme Randomized Controlled Trial Surveys Hemodynamic Excursions During Esophagectomy [NA]
A randomized controlled trial at Erasme University Hospital is examining hemodynamic excursions during esophagectomy, including anesthesia a…
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CLINICAL_TRIALS other · 2024-08-20Clinical Trial Update: A Phase I/II Trial of UCB4594 in Participants With Advanced Cancer [Phase 1, Phase 2]
This entry describes a Phase I/II clinical trial of UCB4594 for multiple advanced solid tumors, including head and neck squamous cell carcin…
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CLINICAL_TRIALS research · 2024-08-16Clinical Trial Update: Reirradiation Dose Escalation in Thoracic Cancers [Phase 1]
Phase 1 trial evaluating dose escalation of reirradiation in thoracic cancers, currently not yet recruiting.
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CLINICAL_TRIALS research · 2024-08-13Clinical Trial Update: HER2 Status in Esophagogastric Adenocarcinoma and Its Associations With Patient's Clinicopathological Outcomes
A clinical trial is investigating HER2 status (HER2-positive vs HER2-low) in esophagogastric adenocarcinoma and its associations with clinic…
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CLINICAL_TRIALS trial_result · 2024-08-13Clinical Trial Update: Tislelizumab Combined With Chemotherapy or Radiotherapy in the Treatment of Advanced or Recurrent Metastatic Elderly Esophageal Cancer [Phase 2]
Phase 2 study evaluating tislelizumab in combination with chemotherapy or radiotherapy for advanced or recurrent metastatic elderly esophage…
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CLINICAL_TRIALS research · 2024-08-09Clinical Trial Update: CEA Targeting Chimeric Antigen Receptor T Lymphocytes (CAR-T) in the Treatment of CEA Positive Advanced Solid Tumors [Phase 1, Phase 2]
This clinical trial update describes an ongoing Phase 1/2 study of CAR-T cells targeting the carcinoembryonic antigen (CEA) for CEA-positive…
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CLINICAL_TRIALS research · 2024-08-09Clinical Trial Update: Impact of Dose to Cardiac Substructures on Survival in Patients With Esophageal Cancer Treated With Radiotherapy or Chemoradiotherapy (SATIATION)
A clinical trial update examining how the radiation dose to cardiac substructures influences survival in patients with esophageal cancer tre…
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CLINICAL_TRIALS trial_result · 2024-08-07Clinical Trial Update: Radiotherapy Assessments During Intervention ANd Treatment (RADIANT)
Clinical trial update for the RADIANT study evaluating radiotherapy assessments during intervention and treatment; the trial covers multiple…
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CLINICAL_TRIALS research · 2024-08-06Clinical Trial Update: MRD-Guided Consolidation Therapy Following Definitive Radiotherapy in Esophageal Cancer [Phase 2]
Phase 2 trial investigating MRD-guided consolidation therapy after definitive radiotherapy in esophageal cancer; currently recruiting.
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CLINICAL_TRIALS withdrawal · 2024-08-05Clinical Trial Update: Phase I/II Evaluation of a Cancer Lysate Vaccine and Montanide(R) ISA-51 VG With Entinostat and Nivolumab as Adjuvant Therapy Following Chemoradiation Therapy With or Without Surgery for Locally Advanced Esophageal Cancer [Phase 1, Phase 2]
Phase I/II trial evaluating a cancer lysate vaccine with Montanide ISA-51 VG, entinostat, and nivolumab as adjuvant therapy after chemoradia…
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CLINICAL_TRIALS research · 2024-07-30Clinical Trial Update: Anti-Migration System for Anti-reflux Oeso-gastric Stent (ANTIMIG) [NA]
Clinical trial update for the Anti-Migration System (ANTIMIG) designed to prevent migration of an anti-reflux esophagogastric stent, with re…
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CLINICAL_TRIALS research · 2024-07-26Clinical Trial Update: TGF-β And PDL-1 Inhibition in Esophageal Squamous Cell Carcinoma Combined With Chemoradiation TheRapY [NA]
A clinical trial evaluating the combination of TGF-β inhibition and PD-L1 inhibition with chemoradiation for esophageal squamous cell carcin…
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CLINICAL_TRIALS trial_result · 2024-07-26Clinical Trial Update: Avelumab With Chemoradiation for Stage II/III Resectable Esophageal and Gastroesophageal Cancer [Phase 1, Phase 2]
A phase 1/2 trial evaluated avelumab with chemoradiation for resectable stage II/III esophageal and gastroesophageal cancer; the study has c…