Esophageal Cancer

• CLINICAL_TRIALS trial_result · 2023-07-13
  Clinical Trial Update: A Clinical Trial of KVA12123 Treatment Alone and in Combination With Pembrolizumab In Advanced Solid Tumors (VISTA-101) [Phase 1, Phase 2]

  Clinical trial update for KVA12123 as a standalone and in combination with pembrolizumab in advanced solid tumors; current status is unknown…

• CLINICAL_TRIALS trial_result · 2023-06-22
  Clinical Trial Update: Combination Chemotherapy After Surgery in Treating Patients With Cancer of the Esophagus or Stomach [Phase 2]

  Phase 2 clinical trial update evaluating combination chemotherapy after surgery in patients with esophageal or gastric cancer.

• CLINICAL_TRIALS trial_result · 2023-06-15
  Clinical Trial Update: Docetaxel Plus Carboplatin in Treating Patients With Advanced Cancer of the Esophagus [Phase 2]

  Phase 2 clinical trial evaluating docetaxel plus carboplatin in advanced esophageal cancer has completed.

• CLINICAL_TRIALS trial_result · 2023-05-25
  Clinical Trial Update: Irinotecan and Taxotere With Radiotherapy as Preoperative Treatment in Resectable Esophageal Cancer [Phase 2]

  Phase 2 trial evaluating preoperative irinotecan and Taxotere with radiotherapy for resectable esophageal cancer has completed.

• CLINICAL_TRIALS trial_result · 2023-05-19
  Clinical Trial Update: Utidelone and Anlotinib in Advanced Recurrent Metastatic Esophageal Cancer [Phase 2]

  Phase 2 clinical trial update evaluating utidelone and anlotinib in advanced recurrent metastatic esophageal cancer.

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• CLINICAL_TRIALS trial_result · 2023-05-09
  Clinical Trial Update: Staging of Superficial EAC Using VLE [NA]

  A clinical trial update on staging superficial esophageal adenocarcinoma using volumetric laser endomicroscopy (VLE) has been terminated; re…

• CLINICAL_TRIALS trial_result · 2023-04-26
  Clinical Trial Update: Early Palliative Care in Patients With Metastatic Upper Gastrointestinal Cancers Treated With First-line Chemotherapy [Phase 3]

  Phase 3 trial evaluating early palliative care in patients with metastatic upper gastrointestinal cancers treated with first-line chemothera…

• CLINICAL_TRIALS trial_result · 2023-04-25
  Clinical Trial Update: Envafolimab Combined With Abraxane and Cisplatinas as Neoadjuvant Treatment for Resectable Esophageal Cancer [Phase 2]

  Phase 2 clinical trial exploring neoadjuvant envafolimab with Abraxane and cisplatin for resectable esophageal cancer.

• CLINICAL_TRIALS trial_result · 2023-04-18
  Clinical Trial Update: Toripalimab Plus Radiotherapy for Elderly Esophageal Cancer Patients Treated With Non-chemotherapy Strategy [Phase 2, Phase 3]

  Phase 2/3 trial investigating toripalimab plus radiotherapy for elderly esophageal cancer patients managed without chemotherapy; status curr…

• CLINICAL_TRIALS trial_result · 2023-03-22
  Clinical Trial Update: Safety and Feasibility of Irradiation and Nivolumab in Esophageal Cancer (INEC) [Phase 1, Phase 2]

  A Phase 1/2 trial assessing safety and feasibility of combining irradiation with nivolumab in esophageal cancer.

• CLINICAL_TRIALS trial_result · 2023-02-16
  Clinical Trial Update: Botulinum Toxin Type A in Preventing Complications After Surgery in Patients With Esophageal Cancer [Phase 2]

  Phase 2 clinical trial evaluating botulinum toxin type A to prevent complications after esophageal cancer surgery.

• CLINICAL_TRIALS trial_result · 2023-02-16
  Clinical Trial Update: FOLFIRI as Second Line Chemotherapy for Metastatic Esophageal Carcinoma [Phase 2]

  Phase 2 trial update evaluating FOLFIRI as second-line chemotherapy for metastatic esophageal carcinoma.

• CLINICAL_TRIALS trial_result · 2023-02-09
  Clinical Trial Update: Phase II Trial of Pembrolizumab With Trastuzumab and Chemotherapy in Advanced HER2 Positive Esophagogastric (EG) Cancer [Phase 2]

  Phase II trial evaluating pembrolizumab with trastuzumab and chemotherapy in advanced HER2-positive esophagogastric cancer has completed and…

• CLINICAL_TRIALS trial_result · 2023-02-08
  Clinical Trial Update: ExeNTrO: Exercise During Neoadjuvant Chemoradiation Treatment to Improve Rectal and Esophageal Cancer Outcome - Pilot Trial [Phase 2]

  A Phase 2 pilot trial examining exercise during neoadjuvant chemoradiation to improve outcomes in rectal and esophageal cancer.

• CLINICAL_TRIALS trial_result · 2023-02-08
  Clinical Trial Update: Carboplatin, Nab-Paclitaxel, Durvalumab Before Surgery and Adjuvant Therapy in Head and Neck Squamous Cell Carcinoma [Phase 2]

  Phase 2 trial evaluating preoperative and adjuvant therapy with carboplatin, nab-paclitaxel, and durvalumab for head and neck squamous cell …

• CLINICAL_TRIALS trial_result · 2023-02-01
  Clinical Trial Update: A Single-Arm Pilot Study of Adjuvant Pembrolizumab Plus Trastuzumab in HER2+ Esophagogastric Tumors With Persistent Circulating Tumor DNA Following Curative Resection [Phase 2]

  Phase 2 single-arm pilot studying adjuvant pembrolizumab plus trastuzumab in HER2-positive esophagogastric tumors with persistent circulatin…

• CLINICAL_TRIALS trial_result · 2023-02-01
  Clinical Trial Update: A Study on the Safety of GEN1044 (DuoBody®-CD3x5T4) in Patients With Malignant Solid Tumors [Phase 1, Phase 2]

  A Phase 1/2 study of GEN1044 (DuoBody-CD3x5T4) in malignant solid tumors has been terminated with posted results.

• CLINICAL_TRIALS trial_result · 2022-12-07
  Clinical Trial Update: Study of SHR-1210 in Combination With Chemotherapy in Advanced Esophageal Cancer [Phase 3]

  Phase 3 trial update of SHR-1210 in combination with chemotherapy in advanced esophageal cancer has completed.

• CLINICAL_TRIALS trial_result · 2022-11-02
  Clinical Trial Update: A Study of T3011 Administered Via Intratumoral Injection in Patients With Advanced Solid Tumors [Phase 1, Phase 2]

  A clinical trial update for T3011 administered intratumorally in advanced solid tumors, including phase 1 and phase 2 cohorts.

• CLINICAL_TRIALS trial_result · 2022-10-04
  Clinical Trial Update: Neo-adjuvant Immunochemotheray Versus Neo-adjuvant Chemotherapy for Resectable Esophageal Carcinoma [Phase 3]

  A Phase 3 clinical trial comparing neoadjuvant immunochemotherapy to neoadjuvant chemotherapy for resectable esophageal carcinoma is current…

• CLINICAL_TRIALS trial_result · 2022-10-04
  Clinical Trial Update: The Efficacy of Neoadjuvant Chemoradiotherapy in Comparison With Neoadjuvant Chemotherapy in Patients With Resectable Squamous Cell Esophageal Cancer [Phase 3]

  A Phase 3 trial comparing neoadjuvant chemoradiotherapy to neoadjuvant chemotherapy in resectable squamous cell esophageal cancer is current…

• CLINICAL_TRIALS trial_result · 2022-09-29
  Clinical Trial Update: A Multicenter Open-label Phase II Trial to Evaluate Nivolumab and Ipilimumab for 2nd Line Therapy in Elderly Patients With Advanced Esophageal Squamous Cell Cancer [Phase 2]

  A multicenter open-label Phase II trial evaluated nivolumab plus ipilimumab as second-line therapy in elderly patients with advanced esophag…

• CLINICAL_TRIALS trial_result · 2022-09-13
  Clinical Trial Update: Safety and Efficacy of CEA-targeted CAR-T for CEA-positive Advanced Malignant Solid Tumors [Phase 1, Phase 2]

  A Phase 1/2 trial evaluating a CEA-targeted CAR-T therapy for CEA-positive advanced solid tumors, with stated gastric, colon, rectal, esopha…

• CLINICAL_TRIALS trial_result · 2022-09-07
  Clinical Trial Update: Bevacizumab and Combination Chemotherapy Before Surgery in Treating Patients With Locally Advanced Esophageal or Stomach Cancer [Phase 2]

  Phase 2 trial evaluating bevacizumab with combination chemotherapy before surgery for locally advanced esophageal or gastroesophageal juncti…

• CLINICAL_TRIALS trial_result · 2022-09-06
  Clinical Trial Update: A Phase II Study of HR070803 in the Treatment of Advanced Esophageal Cancer [Phase 2]

  Phase II study update for HR070803 in advanced esophageal cancer.