Esophageal Cancer

CLINICAL_TRIALS trial_result · 2025-06-13

Clinical Trial Update: Efficacy and Safety Study of Multiple Doses of IMAB362 in Patients With Advanced Gastroesophageal Cancer [Phase 2]

Phase 2 study evaluating efficacy and safety of multiple doses of IMAB362 in patients with advanced gastroesophageal cancer. The trial statu…

CLINICAL_TRIALS trial_result · 2025-06-08

Clinical Trial Update: Testing the Addition of an Anti-cancer Drug, Adavosertib, to Radiation Therapy for Patients With Incurable Esophageal and Gastroesophageal Junction Cancers [Phase 1]

Phase 1 trial updating on the addition of Adavosertib to radiation therapy in patients with incurable esophageal and gastroesophageal juncti…

CLINICAL_TRIALS trial_result · 2025-06-05

Clinical Trial Update: Nasal Mask Kit in Gastrointestinal Endoscopy [NA]

A completed clinical trial evaluating a nasal mask kit used during gastrointestinal endoscopy, with indications including gastric cancer, co…

CLINICAL_TRIALS trial_result · 2025-06-04

Clinical Trial Update: Olaparib and Ramucirumab in Treating Patients With Metastatic or Locally Recurrent Gastric or Gastroesophageal Junction Cancer That Cannot Be Removed by Surgery [Phase 1, Phase 2]

This update covers a Phase 1/2 trial of olaparib plus ramucirumab in patients with metastatic or locally recurrent gastric or gastroesophage…

CLINICAL_TRIALS trial_result · 2025-06-04

Clinical Trial Update: PG2 Concurrent With Chemoradiation for Locally Advanced Esophageal Cancer [Phase 2]

Phase 2 trial evaluating PG2 in combination with chemoradiation for locally advanced esophageal cancer has completed.

CLINICAL_TRIALS trial_result · 2025-05-31

Clinical Trial Update: Retrospective Evaluation of Nivolumab in Adjuvant Esophageal Cancer/Gastroesophageal Junction Cancer

This clinical trial update summarizes a retrospective evaluation of nivolumab as adjuvant therapy for esophageal cancer and gastroesophageal…

CLINICAL_TRIALS trial_result · 2025-05-30

Clinical Trial Update: Study of PD-1 Antibody Combined With Chemoradiotherapy in Oligometastatic Esophageal Cancer [Phase 2]

This Phase 2 trial evaluates a PD-1 antibody in combination with chemoradiotherapy for oligometastatic esophageal cancer and has completed.

CLINICAL_TRIALS trial_result · 2025-05-29

Clinical Trial Update: Study of NGM120 in Subjects With Advanced Solid Tumors, Pancreatic Cancer, and Prostate Cancer Using Combination Therapy [Phase 1, Phase 2]

This update reports results from a Phase 1/2 study of NGM120 in combination therapy for patients with advanced solid tumors, including pancr…

CLINICAL_TRIALS trial_result · 2025-05-28

Clinical Trial Update: Study of PF-06940434 in Patients With Advanced or Metastatic Solid Tumors. [Phase 1]

Pfizer's Phase 1 study of PF-06940434 in advanced or metastatic solid tumors has been terminated. The trial enrolled several solid tumor typ…

CLINICAL_TRIALS trial_result · 2025-05-25

Clinical Trial Update: Transnasal Esophagoscopy (TNE) Esophageal Cancer Screening

The clinical trial evaluating transnasal esophagoscopy for esophageal cancer screening was terminated.

CLINICAL_TRIALS trial_result · 2025-05-21

Clinical Trial Update: COMBO Endoscopy Oropharyngeal Airway in Sedated Gastrointestinal Endoscopy for Obese Patients [Phase 2]

Phase 2 trial of the COMBO Endoscopy Oropharyngeal Airway used during sedated gastrointestinal endoscopy in obese patients has completed rec…

CLINICAL_TRIALS trial_result · 2025-05-18

Clinical Trial Update: Contrast-Enhanced Ultrasound Identification of Sentinel Nodes in Esophageal Cancer [EARLY_Phase 1]

The clinical trial update reports that the EARLY_PHASE1 study using contrast-enhanced ultrasound to identify sentinel nodes in Esophageal ca…

CLINICAL_TRIALS trial_result · 2025-05-16

Clinical Trial Update: A Study of PET Scans With the Radioactive Tracer 18F-BMS-986229 in Patients With Esophageal, Stomach, or Gastroesophageal Junction Cancer

A completed clinical trial evaluating PET imaging with the radiotracer 18F-BMS-986229 in patients with cancers of the esophagus, stomach, or…

CLINICAL_TRIALS trial_result · 2025-05-15

Clinical Trial Update: Real-Time Monitoring of Chemotherapy Side-Effects in Patients With Gastrointestinal Cancers, RT-CAMSS Study [NA]

The RT-CAMSS study, a real-time monitoring trial of chemotherapy side-effects in gastrointestinal cancers, has completed.

CLINICAL_TRIALS trial_result · 2025-05-09

Clinical Trial Update: Clinical Study on the Treatment of Anorexia and Cachexia in Advanced Gastric and Esophageal Cancer With Nanosized Megestrol Acetate Combined With Immunochemotherapy [Phase 4]

A Phase 4 clinical trial from Peking University is evaluating nanosized Megestrol Acetate combined with immunochemotherapy to treat anorexia…

CLINICAL_TRIALS trial_result · 2025-05-08

Clinical Trial Update: A Trial of Durvalumab and Tremelimumab in Combination With SBRT in Patients With Metastatic Cancer [Phase 1, Phase 2]

This clinical trial update reports a completed Phase 1/2 study evaluating durvalumab in combination with tremelimumab and SBRT for metastati…

CLINICAL_TRIALS trial_result · 2025-05-01

Clinical Trial Update: A Phase III, Randomized, Study of Aspirin and Esomeprazole Chemoprevention in Barrett's Metaplasia [Phase 3]

Phase III randomized trial evaluating aspirin plus esomeprazole for chemoprevention in Barrett's esophagus. The study has completed and resu…

CLINICAL_TRIALS trial_result · 2025-04-27

Clinical Trial Update: A Study to Evaluate the Clinical Efficacy of JNJ-42756493 (Erdafitinib), A Pan-Fibroblast Growth Factor Receptor (FGFR) Tyrosine Kinase Inhibitor, In Asian Participants With Advanced Non-Small-Cell Lung Cancer, Urothelial Cancer, Esophageal Cancer Or Cholangiocarcinoma [Phase 2]

A Phase 2 study completed in Asian participants evaluated Erdafitinib, a pan-FGFR tyrosine kinase inhibitor, for efficacy in advanced non-sm…

CLINICAL_TRIALS trial_result · 2025-04-24

Clinical Trial Update: Do Changes in ctDNA Predict Response for Patients With Oesophageal Cancer Receiving Durvalumab [Phase 2]

A Phase 2 clinical trial update evaluating whether changes in circulating tumor DNA predict response in patients with esophageal cancer trea…

CLINICAL_TRIALS trial_result · 2025-04-22

Clinical Trial Update: A Clinical Study of CEA-targeted CAR-T in the Treatment of CEA-positive Advanced Malignant Solid Tumors [Phase 1]

This clinical trial update reports the completion of a Phase 1 study of CEA-targeted CAR-T therapy for CEA-positive advanced solid tumors, i…

CLINICAL_TRIALS trial_result · 2025-04-10

Clinical Trial Update: Genomic Testing and Resulting Medical Decisions

This update reports on a completed clinical trial evaluating genomic testing to guide medical decisions across multiple cancer types, descri…

CLINICAL_TRIALS trial_result · 2025-04-06

Clinical Trial Update: Proton Beam Therapy in the Treatment of Esophageal Cancer [NA]

A clinical trial evaluating proton beam therapy for esophageal cancer reports results as of April 6, 2025, in a Washington University School…

CLINICAL_TRIALS trial_result · 2025-04-03

Clinical Trial Update: Study of Seribantumab in Adult Patients With NRG1 Gene Fusion Positive Advanced Solid Tumors [Phase 2]

A Phase 2 study of seribantumab in adults with NRG1 gene fusion-positive advanced solid tumors has been terminated, with results posted in A…

CLINICAL_TRIALS trial_result · 2025-04-02

Clinical Trial Update: A Phase 1/2, Open-label, Multi-center Study of the Safety and Efficacy of Alomfilimab (KY1044) as Single Agent and in Combination With Anti-PD-L1 (Atezolizumab) in Adult Patients With Selected Advanced Malignancies [Phase 1, Phase 2]

Phase 1/2 open-label study evaluating Alomfilimab (KY1044) alone and with atezolizumab in multiple advanced cancers. The trial was terminate…

CLINICAL_TRIALS trial_result · 2025-04-01

Clinical Trial Update: Methylation Biomarkers for Pioneering Early Esophageal Cancer Detection

A completed clinical trial by Singlera Genomics evaluating methylation biomarkers for early detection of esophageal cancer.

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