Epstein-barr Virus Infection
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-07-09Clinical Trial Update: A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors [Phase 1, Phase 2]
STAR0602, a bifunctional TCR-targeting antibody-fusion, is being studied in a Phase 1/2 trial for advanced solid tumors and related female g…
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CLINICAL_TRIALS trial_result · 2025-07-03Clinical Trial Update: Allogeneic Multivirus - Directed Cytotoxic T Lymphocytes (CTL) [Phase 1]
This is a Phase 1 trial update reporting completion of a study evaluating allogeneic multivirus-directed cytotoxic T lymphocytes for Epstein…
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CLINICAL_TRIALS research · 2025-06-25Clinical Trial Update: Anti-viral T-cell Therapy by Gamma Capture [Phase 1, Phase 2]
Phase 1/2 clinical trial update of an anti-viral T-cell therapy using Gamma Capture for viral infections, currently enrolling by invitation.
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CLINICAL_TRIALS research · 2025-05-15Clinical Trial Update: A Study of an Epstein-Barr Virus (EBV) Candidate Vaccine, mRNA-1189, in 10- to 30-Year-Old Healthy Adolescents and Adults [Phase 1, Phase 2]
A status update on Moderna's Epstein-Barr Virus vaccine candidate mRNA-1189 in Phase 1/2 trials enrolling healthy adolescents and adults, wh…
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CLINICAL_TRIALS research · 2025-05-11Clinical Trial Update: Antiviral Cellular Therapy for Enhancing T-cell Reconstitution Before or After Hematopoietic Stem Cell Transplantation [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/2 study of antiviral cellular therapy intended to enhance T-cell reconstitution around hemato…
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CLINICAL_TRIALS trial_result · 2025-03-20Clinical Trial Update: A Study to Assess Safety and Feasibility of Direct Infusions of Donor-derived Virus-specific T-cells in Recipients of Hematopoietic Stem Cell Transplantation With Post-transplant Viral Infections Using the Cytokine Capture System® [Phase 2]
Phase 2 study evaluating the safety and feasibility of infusing donor-derived virus-specific T cells for post-transplant viral infections in…
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CLINICAL_TRIALS research · 2025-02-25Clinical Trial Update: Occurrence of Antibodies Cross-reacting With Autoantigens in Primary EBV Infection
This clinical trial at University Hospital Basel is investigating antibodies that cross-react with autoantigens during primary Epstein-Barr …
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CLINICAL_TRIALS research · 2024-12-30Clinical Trial Update: KSD-101 Therapy for Standard Treatment Failed EBV-associated Nasopharyngeal Carcinoma: an Exploratory Clinical Trial [EARLY_Phase 1]
Exploratory EARLY_PHASE1 trial of KSD-101 for EBV-associated nasopharyngeal carcinoma; the study is not yet recruiting.
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CLINICAL_TRIALS other · 2024-12-30Clinical Trial Update: R-MVST Cells for Treatment of Viral Infections [Phase 1]
Phase 1 clinical trial evaluating R-MVST cells for the treatment of viral infections, currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-12-27Clinical Trial Update: T Lymphocytes for the Treatment of AdV, CMV, EBV, BKV and Aspergillus Fumigatus Infections After Allogeneic Stem Cell Transplantation [Phase 1, Phase 2]
A completed Phase 1/2 trial evaluating donor-derived T lymphocytes for infections caused by adenovirus, cytomegalovirus, Epstein-Barr virus,…
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CLINICAL_TRIALS research · 2024-11-14Clinical Trial Update: Investigating Epstein-Barr Virus Associated Conjunctivitis
A Moorfields Eye Hospital clinical trial is enrolling participants to study Epstein-Barr virus-associated conjunctivitis.
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CLINICAL_TRIALS trial_result · 2024-11-08Clinical Trial Update: Clinical Performance Evaluation of the NeuMoDx™ EBV Quant Assay 2.0 in Immunocompromised Transplant Patients
A completed clinical trial evaluated the performance of the NeuMoDx EBV Quant Assay 2.0 in immunocompromised transplant patients with Epstei…
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CLINICAL_TRIALS research · 2024-10-30Clinical Trial Update: Study to Evaluate the Efficacy of 2LEBV® and 2LXFS® on Asthenia in Patients With an Epstein-Barr Virus Infection [Phase 4]
A Phase 4 trial to evaluate the efficacy of two products, 2LEBV and 2LXFS, on asthenia in patients with Epstein-Barr virus infection, curren…
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CLINICAL_TRIALS research · 2024-08-28Clinical Trial Update: Adoptive Cord Blood Immunotherapy for EBV, CMV, BKV and Adenovirus Reactivation/Infection or Prophylaxis [Phase 1, Phase 2]
The document describes a Phase 1/2 clinical trial evaluating adoptive cord blood immunotherapy to prevent or treat reactivation/infection wi…
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CLINICAL_TRIALS research · 2024-08-15Clinical Trial Update: Evaluation of CMV/EBV-CMI in Haploid HSCT
A study evaluating CMV/EBV-specific cellular immune responses in haploid hematopoietic stem cell transplantation is currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-05-16Clinical Trial Update: Study of Posoleucel (ALVR105,Viralym-M) for Multi-Virus Prevention in Patients Post-Allogeneic Hematopoietic Cell Transplant [Phase 2, Phase 3]
Clinical trial update reports termination of a Phase 2/Phase 3 study of posoleucel (ALVR105, Viralym-M) for multi-virus prevention in patien…
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CLINICAL_TRIALS trial_result · 2022-01-05Clinical Trial Update: PD1 Antibody and Lenalidomide as a Treatment for EBV-HLH or CAEBV [Phase 3]
Phase 3 trial updating PD-1 antibody plus lenalidomide for EBV-related diseases is underway, status not yet disclosed.
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CLINICAL_TRIALS trial_result · 2021-09-09Clinical Trial Update: Programmed Cell Death Protein-1 (PD-1) Monoclonal Antibody for EBV-HLH and CAEBV as First-line Therapy [Phase 4]
A Phase 4 clinical trial update investigating a PD-1 monoclonal antibody as first-line therapy for EBV-related hemophagocytic lymphohistiocy…
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CLINICAL_TRIALS trial_result · 2018-07-17Clinical Trial Update: A Phase Ib Trial of MVA-EBNA1/LMP2 Vaccine in Nasopharyngeal Carcinoma [Phase 1]
Phase Ib trial evaluating the MVA-EBNA1/LMP2 vaccine for nasopharyngeal carcinoma has been completed.
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Effects of Long-Term Treatment With Valaciclovir (Valtrex) on Epstein-Barr Virus
This completed trial evaluated the effects of long-term valacyclovir (Valtrex) treatment on Epstein-Barr virus activity. The study included …
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CLINICAL_TRIALS research · 2017-07-02Clinical Trial Update: Protein Studies of the Epstein-Barr Virus in Ethnically Diverse Populations
The NIH-sponsored clinical trial examining Epstein-Barr virus protein studies across ethnically diverse populations has completed.
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CLINICAL_TRIALS trial_result · 2017-06-28Clinical Trial Update: Chronic Fatigue Following Acute Epstein-Barr Virus Infection in Adolescents
This update notes that a clinical trial examining chronic fatigue following acute Epstein-Barr virus infection in adolescents has completed.
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CLINICAL_TRIALS trial_result · 2016-08-25Clinical Trial Update: Differences Between Chidamide Taken Daily and Twice a Week in Therapeutic Effect，Pharmacokinetics, Pharmacodynamics and EB Virus Activation [Phase 2]
Phase 2 trial comparing daily versus twice-weekly dosing of chidamide and evaluating differences in therapeutic effect, pharmacokinetics/pha…
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CLINICAL_TRIALS research · 2016-07-21Clinical Trial Update: Partially HLA-matched Third Party Antigen Specific T-cells for Infection Post-stem Cell or Solid Organ Transplantation [Phase 1]
Phase 1 clinical trial evaluating partially HLA-matched third-party antigen-specific T-cells for preventing or treating CMV, EBV, and adenov…
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CLINICAL_TRIALS trial_result · 2016-06-10Clinical Trial Update: Nelfinavir for the Treatment of Gammaherpesvirus-Related Tumors [EARLY_Phase 1]
Early-phase 1 clinical trial update for nelfinavir in gammaherpesvirus-related tumors, noting termination of the study despite investigation…