Epilepsy
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Microelectrode Recordings From the Vagus Nerve in Awake Humans [Phase 1]
Phase 1 trial exploring microelectrode recordings from the vagus nerve in awake humans for epilepsy. Recruitment is ongoing.
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Methylphenidate for the Treatment of Epilepsy-related Cognitive Deficits [Phase 4]
A Phase 4 clinical trial is evaluating methylphenidate for epilepsy-related cognitive deficits and is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Genetic and Electrophysiologic Study in Focal Drug-resistant Epilepsies
This ClinicalTrials.gov update outlines a genetic and electrophysiologic study investigating drug-resistant focal epilepsies in pediatric pa…
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CLINICAL_TRIALS trial_result · 2026-04-17Clinical Trial Update: Coenzyme Q10 as Adjunctive Therapy in Drug-Resistant Epilepsy [NA]
A completed clinical trial evaluated Coenzyme Q10 as an adjunctive therapy for drug-resistant epilepsy.
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: Patterns of Neurodevelopmental Disorders
This clinical trial update reports that a Richard Frye-sponsored study on patterns of neurodevelopmental disorders, including autism spectru…
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CLINICAL_TRIALS trial_result · 2026-04-15Clinical Trial Update: Impact of Thermocoagulation During Invasive EEG Monitoring in Children With Focal Drug-resistant Epilepsies [NA]
This clinical trial update reports a completed study evaluating the use of thermocoagulation during invasive EEG monitoring in children with…
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CLINICAL_TRIALS trial_result · 2026-04-15Clinical Trial Update: Evaluation of Optical Pumping Magnetometer Sensors for MagnetoEncephaloGraphy Imaging [NA]
A completed study evaluating optical pumping magnetometer sensors for magnetoencephalography imaging in epilepsy.
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: S100B Protein: a Diagnostic Aid in Episodes of Transient Loss of Consciousness?
A clinical trial is evaluating whether measuring S100B protein can serve as a diagnostic aid during episodes of transient loss of consciousn…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Noninvasive Pre-surgical Evaluation of Patients With Focal Epilepsy and Establishment of a Normative Imaging Database
This clinical trial investigates noninvasive methods for pre-surgical evaluation in patients with focal epilepsy and aims to establish a nor…
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FDA approval · 2026-04-13FDA Approved: LAMOTRIGINE — Supplemental Application (Alembic Pharmaceuticals Limited)
FDA approved a supplemental application for Lamotrigine from Alembic Pharmaceuticals Limited under ANDA 090607.
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Effects of Mega-dose Vitamin D Pulse and Maintenance Therapy on Seizure Frequency, Fatigue, and Quality of Life: A Prospective Study [NA]
A prospective study evaluating mega-dose Vitamin D pulse therapy with maintenance in people with epilepsy. The trial aims to assess effects …
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Combined CM and STN Stimulation for Motor Epilepsy [NA]
The trial investigates combined centromedian (CM) and subthalamic nucleus (STN) stimulation as a treatment for motor epilepsy. It is not yet…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: An Open-label Study of XEN1101 in Epilepsy [Phase 3]
An open-label Phase 3 study evaluating XEN1101 for epilepsy is underway, with enrollment by invitation.
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EMA safety_alert · 2026-04-10Meeting highlights from the Pharmacovigilance Risk Assessment Committee (PRAC) 7-10 April 2026
PRAC agreed to issue a communication to healthcare professionals about cases of severe liver injury linked to epilepsy medicines.
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FDA approval · 2026-04-10FDA Approved: LAMOTRIGINE KIT — Supplemental Application (OWP Pharmaceuticals, Inc.)
FDA approved a supplemental application for Lamotrigine Kit, a generic lamotrigine product by OWP Pharmaceuticals, Inc.
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FDA approval · 2026-04-09FDA Approved: LAMOTRIGINE — Supplemental Application (Aurobindo Pharma Limited)
FDA approved a supplemental application for Lamotrigine submitted by Aurobindo Pharma Limited.
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CLINICAL_TRIALS trial_result · 2026-04-09Clinical Trial Update: RNS® System Epilepsy Post-Approval Study
This document reports the completion of NeuroPace's post-approval study of the RNS System for epilepsy.
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Cholinergic Enhancement of Theta [EARLY_Phase 1]
This is an early-phase 1 trial evaluating cholinergic enhancement of theta activity in epilepsy-related cognitive conditions. The study stat…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: MiCrobiota-gut-brain Axis in Resistant Epilepsy [NA]
A clinical trial exploring the gut microbiota–brain axis in drug-resistant epilepsy is currently recruiting at Niguarda Hospital.
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: A Safety, Tolerability, and Preliminary Efficacy of Low-intensity Focused Ultrasound Neuromodulation in Patients With Drug-resistant Epilepsy [Phase 1, Phase 2]
NaviFUS Corporation is conducting a Phase 1/2 clinical trial to evaluate the safety, tolerability, and preliminary efficacy of low-intensity…
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CLINICAL_TRIALS trial_result · 2026-04-09Clinical Trial Update: NaviFUS™ System Neuromodulating Treatment for Patients With Drug Resistant Epilepsy [NA]
A completed clinical trial evaluating the NaviFUS neuromodulation system for patients with drug-resistant epilepsy.
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Intracranial Stimulation Mapping In Epilepsy [NA]
This clinical trial update reports recruitment for a study on intracranial stimulation mapping in epilepsy, sponsored by the University of M…
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CLINICAL_TRIALS trial_result · 2026-04-09Clinical Trial Update: Observational Study on Dynamic Changes of Blood Pressure During Post-epileptic Seizure Stage (OCBPS)
This is a completed observational study from Xuanwu Hospital in Beijing examining how blood pressure changes during the post-seizure period …
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FDA approval · 2026-04-09FDA Approved: LAMOTRIGINE — Supplemental Application (Unichem Pharmaceuticals (USA), Inc.)
FDA approved a supplemental application for a generic lamotrigine product from Unichem Pharmaceuticals (USA), Inc.
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Lily's Grace Temporal Interference [NA]
This clinical trial update notes a not-yet-recruiting epilepsy study titled 'Lily's Grace Temporal Interference' sponsored by the University…