Epilepsy
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CLINICAL_TRIALS trial_result · 2011-03-17Clinical Trial Update: Multicenter Trial for Adults With Partial Seizures [Phase 2]
Phase 2 multicenter trial in adults with partial seizures (epilepsy) sponsored by Teva; the study status is completed.
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CLINICAL_TRIALS trial_result · 2011-03-08Clinical Trial Update: Transcutaneous Non-invasive Stimulation of the Vagus Nerve for the Treatment of Difficult-to-treat Epilepsy [NA]
This entry notes the completion of a clinical trial evaluating transcutaneous non-invasive vagus nerve stimulation for difficult-to-treat ep…
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CLINICAL_TRIALS trial_result · 2011-02-25Clinical Trial Update: Open-label Study of Levetiracetam Intravenous Infusion in Children (1 Month-4 Years Old) With Epilepsy [Phase 2]
An open-label Phase 2 study evaluating intravenous levetiracetam in children aged 1 month to 4 years with epilepsy has completed and posted …
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CLINICAL_TRIALS trial_result · 2011-02-25Clinical Trial Update: Open-label Study of Levetiracetam Intravenous Infusion in Children (4-16 Years Old) With Epilepsy [Phase 2]
An open-label Phase 2 study evaluating intravenous levetiracetam in children aged 4-16 with epilepsy; results were posted in 2011.
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CLINICAL_TRIALS trial_result · 2011-01-24Clinical Trial Update: Heart Rate Changes During Normal Activity, Exercise, and Sleep in Normal Healthy Subjects With and Without Epilepsy
This completed trial evaluated heart rate changes during rest, exercise, and sleep in healthy subjects, comparing those with epilepsy to tho…
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CLINICAL_TRIALS trial_result · 2010-12-20Clinical Trial Update: Conversion to Monotherapy Study With Keppra XR for Partial Seizures [Phase 3]
Phase 3 trial evaluating conversion to Keppra XR monotherapy for partial seizures in epilepsy; results from the completed study have been po…
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CLINICAL_TRIALS trial_result · 2010-11-23Clinical Trial Update: Characterization of Epileptic Motor Patterns by Tridimensional Analysis of Movement 2 [NA]
The study evaluating tridimensional analysis of motor patterns in epileptic seizures was terminated; the update notes the status rather than…
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CLINICAL_TRIALS trial_result · 2010-11-15Clinical Trial Update: A Study of the Effectiveness and Safety of Topiramate Monotherapy in Patients With Recently Diagnosed Partial-Onset Seizure [Phase 3]
Phase 3 trial evaluating the effectiveness and safety of topiramate as monotherapy for recently diagnosed partial-onset seizures has complet…
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CLINICAL_TRIALS trial_result · 2010-10-20Clinical Trial Update: Safety of Intravenous Lacosamide Dose Followed by Twice Daily Oral Lacosamide in Subjects With Partial-onset Seizures [Phase 3]
Phase 3 trial update reports safety findings for intravenous lacosamide followed by twice-daily oral lacosamide in adults with partial-onset…
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CLINICAL_TRIALS trial_result · 2010-08-26Clinical Trial Update: Study of an External Responsive Neurostimulator System on Epileptiform Activity [Phase 2]
Phase 2 study of the External Responsive Neurostimulator System for epilepsy has completed.
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CLINICAL_TRIALS trial_result · 2010-07-09Clinical Trial Update: Tolerability and Efficacy of Depakote-extended Release in the Elderly [NA]
A completed clinical trial evaluating tolerability and efficacy of Depakote extended-release in elderly patients with epilepsy/seizures.
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CLINICAL_TRIALS trial_result · 2010-06-24Clinical Trial Update: Non-Interventional Study With LYRICA (Pregabalin) In Patients With Epilepsy As Adjunctive Therapy Of Partial Seizures To Reduce Seizure Frequency
A completed non-interventional study evaluating pregabalin (LYRICA) as adjunctive therapy for partial seizures in epilepsy; results posted i…
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CLINICAL_TRIALS trial_result · 2010-05-27Clinical Trial Update: Use of the Atkins Diet for Children With Sturge Weber Syndrome [Phase 1]
A Phase 1 clinical trial evaluated the Atkins diet as a dietary intervention for epilepsy in children with Sturge-Weber syndrome; the study …
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CLINICAL_TRIALS trial_result · 2010-05-25Clinical Trial Update: A Study of the Pharmacokinetics, Safety and Tolerability of Topiramate in Infants (Age 1-24 Months) With Refractory Partial-onset Seizures [Phase 1]
Completed Phase 1 study assessing pharmacokinetics, safety and tolerability of topiramate in infants aged 1-24 months with refractory partia…
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CLINICAL_TRIALS trial_result · 2010-05-24Clinical Trial Update: The Study of NPC-06 - Investigation of Safety, Efficacy and Pharmacokinetics of Fosphenytoin [Phase 3]
Phase 3 clinical trial update for NPC-06 evaluating the safety, efficacy, and pharmacokinetics of fosphenytoin in epilepsy has completed.
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CLINICAL_TRIALS trial_result · 2010-05-18Clinical Trial Update: Study Evaluating LAMICTAL Extended-Release Therapy Added To Current Seizure Treatments In Patients With Primary Generalized Tonic-Clonic Seizures (PGTC) Seizures [Phase 3]
A Phase 3 study evaluating Lamictal Extended-Release as add-on therapy for primary generalized tonic-clonic seizures has completed and resul…
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CLINICAL_TRIALS trial_result · 2010-05-17Clinical Trial Update: Study Comparing Best Medical Practice With or Without VNS Therapy in Pharmacoresistant Partial Epilepsy Patients [Phase 4]
Phase 4 clinical trial comparing best medical practice with or without vagus nerve stimulation in pharmacoresistant partial epilepsy; the st…
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CLINICAL_TRIALS trial_result · 2010-04-28Clinical Trial Update: Prospective Pilot Study on Metabolism and Weight Changes in Topiramate-Treated Epilepsy Patients [Phase 3]
A Phase 3 pilot trial evaluating metabolism and weight changes in epilepsy patients treated with topiramate has completed.
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CLINICAL_TRIALS trial_result · 2010-04-27Clinical Trial Update: An Observational Study of the Safety of Topiramate in Adults and Children With Epilepsy
This is an observational safety study evaluating topiramate in adults and children with epilepsy, reporting safety outcomes from a completed…
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CLINICAL_TRIALS trial_result · 2010-04-27Clinical Trial Update: A Study of the Prevalence of Headache in Epileptic Patients
A completed clinical trial studying the prevalence of headache among patients with epilepsy.
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CLINICAL_TRIALS trial_result · 2010-04-23Clinical Trial Update: A Study of the Pharmacokinetics (PK) and Safety of IV Carbamazepine Relative to Oral Carbamazepine in Adults With Epilepsy [Phase 1]
Phase 1 study analyzes pharmacokinetics and safety of intravenous carbamazepine relative to oral carbamazepine in adults with epilepsy. The …
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CLINICAL_TRIALS trial_result · 2010-02-23Clinical Trial Update: Early Surgical Intervention to Treat Epilepsy [Phase 3]
A Phase 3 trial sponsored by UCLA evaluated early surgical intervention for epilepsy, specifically temporal lobe epilepsy. The study status …
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CLINICAL_TRIALS trial_result · 2010-02-03Clinical Trial Update: Thalidomide Low Threshold in Epilepsy [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating thalidomide for refractory epilepsy has completed, with results posted in 2010. The study was sponsored …
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CLINICAL_TRIALS trial_result · 2010-01-27Clinical Trial Update: Use of the Atkins Diet for Adults With Intractable Epilepsy [NA]
A completed clinical trial assessed the Atkins diet as a treatment option for adults with intractable epilepsy. The study was sponsored by J…
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CLINICAL_TRIALS trial_result · 2010-01-20Clinical Trial Update: Fasted Bioequivalence Study of Primidone Tablets and Mysoline Tablets [Phase 1]
Phase 1 fasting bioequivalence study comparing Primidone tablets and Mysoline tablets to establish therapeutic equivalence.