Epilepsy
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2014-08-08Clinical Trial Update: Comparative Study Of Pregabalin And Gabapentin As Adjunctive Therapy In Subjects With Partial Seizures [Phase 4]
Phase 4 comparative study of pregabalin vs gabapentin as adjunctive therapy in partial seizures completed with results posted in 2014.
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CLINICAL_TRIALS trial_result · 2014-08-07Clinical Trial Update: Heart Rate Changes in Subjects With Epilepsy
A completed clinical trial evaluated heart rate changes in epilepsy patients treated with vagus nerve stimulation (VNS Therapy), with result…
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CLINICAL_TRIALS trial_result · 2014-08-07Clinical Trial Update: 3-Dimensional Accelerometer Sub-Study [NA]
This document notes the completion of a 3-Dimensional Accelerometer Sub-Study within an epilepsy trial sponsored by Cyberonics.
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CLINICAL_TRIALS trial_result · 2014-08-04Clinical Trial Update: Long-term, Open-label Safety Extension Study of Retigabine/Ezogabine in Pediatric Subjects (>= 12 Years Old) With POS or LGS [Phase 3]
Phase 3 long-term open-label safety extension for retigabine/ezogabine in pediatric subjects with epilepsy has been terminated; results post…
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CLINICAL_TRIALS trial_result · 2014-07-18Clinical Trial Update: Safety and Efficacy of Eslicarbazepine Acetate as Adjunctive Therapy for Partial Seizures in Elderly Patients [Phase 3]
This update reports the completion of a Phase 3 trial evaluating eslicarbazepine acetate as add-on therapy for partial seizures in elderly p…
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CLINICAL_TRIALS trial_result · 2014-07-01Clinical Trial Update: Study of Intranasal Clonazepam in Adult Subjects With Epileptic Seizures [Phase 2]
A Phase 2 trial evaluating intranasal clonazepam for adult epileptic seizures has completed, and results were posted in 2014.
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CLINICAL_TRIALS trial_result · 2014-06-27Clinical Trial Update: Efficacy and Safety of an add-on Treatment With Zonisamide in Adults With Focal Epileptic Seizures With or Without Secondary Generalization [Phase 4]
Phase 4 trial evaluating add-on zonisamide for adults with focal epilepsy (with or without secondary generalization); the study assessing ef…
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CLINICAL_TRIALS trial_result · 2014-06-26Clinical Trial Update: Trial to Assess Vagus Nerve Stimulation Therapy vs. Anti-Epileptic Drug (AED) Treatment in Children With Refractory Seizures [Phase 4]
Phase 4 trial comparing vagus nerve stimulation therapy to anti-epileptic drug treatment in children with refractory seizures; the study was…
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CLINICAL_TRIALS trial_result · 2014-06-20Clinical Trial Update: A Study of Diazepam After Intranasal and Intravenous Administration to Healthy Volunteers [Phase 1]
Phase 1 study examining diazepam administration routes (intranasal and intravenous) in healthy volunteers; completed with results posted in …
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CLINICAL_TRIALS trial_result · 2014-05-23Clinical Trial Update: Study on Migraine and Headache in Epileptic Patients
The clinical trial evaluating migraine and headache in epileptic patients has completed. No specific drug names are provided in the excerpt.
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CLINICAL_TRIALS trial_result · 2014-05-22Clinical Trial Update: Development and Clinical Application of [11C]Verapamil-PET [Phase 2]
Phase 2 trial update on using [11C]Verapamil-PET imaging for epilepsy.
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CLINICAL_TRIALS trial_result · 2014-05-13Clinical Trial Update: Combined Role of Position Emission Tomography (PET) and Magnetoencephalography (MEG) in Nonlesional Epilepsy [Phase 3]
Phase 3 clinical trial evaluating the combined use of PET and MEG for nonlesional epilepsy has completed.
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CLINICAL_TRIALS trial_result · 2014-05-07Clinical Trial Update: Study to Evaluate the Safety and Effectiveness of USL255 in Patients With Refractory Partial-onset Seizures [Phase 3]
Phase 3 study evaluating USL255 for refractory partial-onset seizures has completed. Results were posted in 2014.
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CLINICAL_TRIALS trial_result · 2014-04-23Clinical Trial Update: Trial to Demonstrate the Efficacy and Safety of Conversion to Lacosamide Monotherapy for Partial-onset Seizures [Phase 3]
Phase 3 trial results evaluate converting to lacosamide monotherapy for partial-onset seizures, reporting on efficacy and safety.
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CLINICAL_TRIALS trial_result · 2014-04-03Clinical Trial Update: Double-blind Study in Paediatric Epileptic to Compare the Subject Preference for ESL Suspension Formulation With Alternative Flavours [Phase 2]
Phase 2 double-blind study in pediatric epilepsy comparing subject flavor preference for an eslicarbazepine acetate suspension formulation (…
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CLINICAL_TRIALS trial_result · 2014-03-27Clinical Trial Update: Biomarkers In Seizure To Predict Recurrence and Severe Outcomes
Completed clinical trial evaluating biomarkers S-100b and copeptin to predict seizure recurrence and severe outcomes.
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CLINICAL_TRIALS trial_result · 2014-03-26Clinical Trial Update: Topiramate as Adjunctive Therapy in Infants 1-24 Months for the Control of Partial Onset Seizures [Phase 3]
Phase 3 study evaluating adjunctive topiramate in infants aged 1–24 months for partial-onset seizures has completed.
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CLINICAL_TRIALS trial_result · 2014-03-17Clinical Trial Update: Controlled Randomized Vagus Nerve Stimulation (VNS) Therapy Versus Resection (CoRaVNStiR) [NA]
Clinical trial comparing vagus nerve stimulation therapy to surgical resection for epilepsy; current status is unknown.
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CLINICAL_TRIALS trial_result · 2014-02-27Clinical Trial Update: The Effect of BIA 2-093 on the Steady-state Pharmacokinetic Profile of Phenytoin in Patients [Phase 1]
Phase 1 study evaluating the effect of BIA 2-093 on the steady-state pharmacokinetics of phenytoin in patients with epilepsy. The trial stat…
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CLINICAL_TRIALS trial_result · 2014-02-14Clinical Trial Update: Animal Assisted Therapy in a Pediatric Setting [Phase 1, Phase 2]
Clinical trial update indicates an animal-assisted therapy study in a pediatric setting completed Phase 1 and Phase 2 trials across several …
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CLINICAL_TRIALS trial_result · 2014-02-12Clinical Trial Update: Mindfulness-based Psychotherapy for Drug-resistant Epilepsy [NA]
A completed clinical trial evaluating mindfulness-based psychotherapy for drug-resistant epilepsy.
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CLINICAL_TRIALS trial_result · 2014-02-12Clinical Trial Update: Preventing Depression in People With Epilepsy: an Extension of Project UPLIFT [NA]
This is a completed extension study of Project UPLIFT focused on preventing depressive symptoms in people with epilepsy.
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CLINICAL_TRIALS trial_result · 2014-01-31Clinical Trial Update: Efficacy of YKP3089 in Patients With Photosensitive Epilepsy [Phase 2]
This update reports the completion of a Phase 2 trial evaluating the efficacy of YKP3089 in patients with photosensitive epilepsy.
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CLINICAL_TRIALS trial_result · 2014-01-29Clinical Trial Update: Evaluation of Individual Bioequivalence of Gabasandoz® Relative to Neurontin® in Healthy Volunteers [Phase 1]
Phase 1 bioequivalence study comparing Gabasandoz to Neurontin (gabapentin) in healthy volunteers has completed.
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CLINICAL_TRIALS trial_result · 2014-01-14Clinical Trial Update: Brain Stimulation for Epilepsy Long Term Follow-up
Long-term follow-up results from a brain stimulation trial for epilepsy have been reported. The update indicates continued safety and effect…