Epilepsy
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CLINICAL_TRIALS trial_result · 2014-12-08Clinical Trial Update: Study of Human Sensory Perception
This entry reports a completed clinical trial update for a study on human sensory perception sponsored by Swedish Medical Center in people w…
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CLINICAL_TRIALS trial_result · 2014-12-03Clinical Trial Update: Disposition of Eslicarbazepine Acetate and Its Metabolites S-licarbazepine and R-licarbazepine [Phase 1]
Phase 1 trial update reporting the disposition of eslicarbazepine acetate and its metabolites S-licarbazepine and R-licarbazepine, with resu…
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CLINICAL_TRIALS trial_result · 2014-12-03Clinical Trial Update: Effect of BIA 2-093 on the Pharmacokinetics of a Combined Oral Contraceptive. [Phase 1]
Phase 1 trial evaluating the effect of BIA 2-093 on the pharmacokinetics of a combined oral contraceptive; results were posted.
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CLINICAL_TRIALS trial_result · 2014-12-02Clinical Trial Update: Cortical Excitability Changes Induced by Retigabine: a Transcranial Magnetic Stimulation Study [Phase 3]
Phase 3 study results examining how retigabine (ezogabine) affects cortical excitability as measured by transcranial magnetic stimulation in…
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CLINICAL_TRIALS trial_result · 2014-12-02Clinical Trial Update: Trial of Melatonin to Improve Sleep in Children With Epilepsy and Neurodevelopmental Disabilities [Phase 3]
Phase 3 clinical trial evaluating melatonin to improve sleep in children with epilepsy and neurodevelopmental disabilities has completed.
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CLINICAL_TRIALS trial_result · 2014-12-01Clinical Trial Update: The Effect of BIA 2-093 on the Steady-state Pharmacodynamic and Pharmacokinetic Profiles of Warfarin [Phase 1]
Phase 1 trial assessing the effect of BIA 2-093 on the steady-state pharmacodynamic and pharmacokinetic profiles of warfarin, with results p…
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CLINICAL_TRIALS trial_result · 2014-11-26Clinical Trial Update: eValuation of the Efficacy and toleRability of Vimpat When Added to lEvetiracetam [Phase 3]
Phase 3 trial evaluating the efficacy and tolerability of adding lacosamide (Vimpat) to levetiracetam in epilepsy has completed with results…
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CLINICAL_TRIALS trial_result · 2014-11-21Clinical Trial Update: Cerebral Metabolic Changes Associated With Thalamic Stimulation [Phase 3]
This clinical trial update notes cerebral metabolic changes associated with thalamic stimulation in a Phase 3 study for epilepsy. The trial …
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CLINICAL_TRIALS trial_result · 2014-11-19Clinical Trial Update: Observational Study in Infants Who Are Prescribed Treatment With Keppra® (Levetiracetam) Oral Solution
This document reports the completion and posting of results for an observational study of infants prescribed Keppra (levetiracetam) oral sol…
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CLINICAL_TRIALS trial_result · 2014-11-05Clinical Trial Update: Open-label Drug Interaction Study Between Eslicarbazepine Acetate and Lamotrigine. [Phase 1]
Open-label Phase 1 study evaluating drug interaction between eslicarbazepine acetate and lamotrigine in epilepsy; study completed.
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CLINICAL_TRIALS trial_result · 2014-10-17Clinical Trial Update: Enteral Levetiracetam For Seizure Control In Pediatric Cerebral Malaria [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating enteral levetiracetam for seizure control in pediatric cerebral malaria has completed with results poste…
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CLINICAL_TRIALS trial_result · 2014-10-13Clinical Trial Update: An Open Label Study of Levetiracetam Monotherapy in Patients With Newly Diagnosed Focal Epilepsy [Phase 3]
Phase 3 open-label study assessing levetiracetam monotherapy in patients with newly diagnosed focal epilepsy.
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CLINICAL_TRIALS trial_result · 2014-10-01Clinical Trial Update: REMS Retigabine Study
A REMS-related clinical trial update for retigabine (ezogabine) in epilepsy has completed. The study was sponsored by GlaxoSmithKline.
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CLINICAL_TRIALS trial_result · 2014-09-22Clinical Trial Update: Safety and Tolerability of Intravenous SPM 927 as Replacement for Oral SPM 927 in Subjects With Partial Seizures [Phase 2, Phase 3]
This clinical trial update reports on the safety and tolerability of intravenous SPM 927 as a replacement for oral SPM 927 in subjects with …
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CLINICAL_TRIALS trial_result · 2014-09-22Clinical Trial Update: SPM 927 (400mg/Day and 600mg/Day) as Adjunctive Therapy in Subjects With Partial Seizures With or Without Secondary Generalization [Phase 3]
A Phase 3 trial evaluating SPM 927 as adjunctive therapy for partial seizures (with or without secondary generalization) completed, sponsore…
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CLINICAL_TRIALS trial_result · 2014-09-17Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Add-on Therapy of Wuling Capsule in Epilepsy Patients With Depression [NA]
A completed study evaluated adding Wuling Capsule to standard therapy for patients with epilepsy and depression.
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CLINICAL_TRIALS trial_result · 2014-09-16Clinical Trial Update: Human Tissue Distribution of Orally Supplemented Natural Vitamin E Tocotrienol [EARLY_Phase 1]
Early Phase 1 trial evaluating tissue distribution of orally administered natural vitamin E tocotrienol across subjects with end-stage heart…
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CLINICAL_TRIALS trial_result · 2014-09-08Clinical Trial Update: Assessment of the Efficacy and Safety of 2 Doses of Retigabine Immediate Release (900 mg/Day and 600 mg/Day) Used as Adjunctive Therapy in Adult Asian Subjects With Drug-resistant Partial-onset Seizures [Phase 3]
A Phase 3 trial evaluating two doses of immediate-release retigabine (900 mg/day and 600 mg/day) as adjunctive therapy in adult Asian subjec…
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CLINICAL_TRIALS trial_result · 2014-09-04Clinical Trial Update: Study in Pediatric Subjects With Epilepsy [Phase 2]
Phase 2 clinical trial in pediatric epilepsy subjects was terminated; results posted in 2014.
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CLINICAL_TRIALS trial_result · 2014-09-01Clinical Trial Update: IVIG Treatment for Refractory Immune-Related Adult Epilepsy [Phase 2]
Phase 2 trial of intravenous immunoglobulin (IVIG) for refractory immune-related epilepsy was terminated. Results have been posted.
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CLINICAL_TRIALS trial_result · 2014-09-01Clinical Trial Update: Pharmacokinetics, Efficacy and Tolerability of BIA 2-093 [Phase 2]
Phase 2 clinical trial update on pharmacokinetics, efficacy, and tolerability of BIA 2-093 in epilepsy completed with results posted in 2014…
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CLINICAL_TRIALS trial_result · 2014-08-27Clinical Trial Update: Clinical Study of Lamotrigine to Treat Newly Diagnosed Typical Absence Seizure in Children and Adolescents [Phase 3]
Phase 3 clinical study of lamotrigine for newly diagnosed typical absence seizures in children and adolescents has completed, with results p…
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CLINICAL_TRIALS trial_result · 2014-08-27Clinical Trial Update: Revisiting Survey Investigating Why Patients Are Not Receiving Home Anti-convulsant Medication Prior to Surgery/or Procedure Involving General Anesthesia
A completed clinical trial update investigates why patients are not taking home anti-convulsant medications before surgery or procedures inv…
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CLINICAL_TRIALS trial_result · 2014-08-12Clinical Trial Update: A Study of Levetiracetam in Japanese Pediatric Patients With Generalized Tonic-clonic Seizures [Phase 3]
Phase 3 study of levetiracetam in Japanese pediatric patients with generalized tonic-clonic seizures has completed. Results have been posted…
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CLINICAL_TRIALS trial_result · 2014-08-12Clinical Trial Update: A Placebo-controlled Study to Investigate Safety and Efficacy of BIA 2-093 [Phase 2]
A phase 2, placebo-controlled trial evaluating the safety and efficacy of BIA 2-093 in epilepsy has completed and results have been posted.