Epilepsy
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CLINICAL_TRIALS trial_result · 2016-08-31Clinical Trial Update: Methylphenidate Treatment of Attention Deficits in Epilepsy [Phase 4]
This update reports results from a Phase 4 trial evaluating methylphenidate for attention deficits in people with epilepsy; the study is com…
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CLINICAL_TRIALS trial_result · 2016-08-24Clinical Trial Update: Retrospective Evaluation of Perampanel in a French Neurology and Epileptology Department (Hospices Civil de Lyon)
A retrospective evaluation of perampanel use in patients with refractory epilepsy at a French neurology and epileptology department summariz…
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CLINICAL_TRIALS trial_result · 2016-08-16Clinical Trial Update: Efficacy and Safety of Diazepam in the Management of Refractory Epilepsy in Selected Patients Who Require Intermittent Medical Intervention for Acute Repetitive Seizures. [Phase 3]
Phase 3 trial evaluating diazepam for management of refractory epilepsy in patients requiring intermittent medical intervention for acute re…
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CLINICAL_TRIALS trial_result · 2016-08-15Clinical Trial Update: Effect of Brivaracetam (BRV) on Nonpsychotic Behavioral Side Effects in Subjects Treated Previously With Levetiracetam (LEV) [Phase 3]
A Phase 3 trial evaluating whether Brivaracetam reduces nonpsychotic behavioral side effects in epilepsy patients previously treated with Le…
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CLINICAL_TRIALS trial_result · 2016-08-15Clinical Trial Update: Brivaracetam Efficacy and Safety Study in Subjects With Partial Onset Seizures [Phase 3]
Phase 3 trial update on brivaracetam for partial onset seizures reports efficacy and safety results.
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CLINICAL_TRIALS trial_result · 2016-08-11Clinical Trial Update: Open-label, Randomized, Active-controlled Study of LEV Used as Monotherapy in Patients With Partial-Onset Seizures [Phase 3]
A Phase 3 open-label, randomized, active-controlled study evaluating levetiracetam as monotherapy for partial-onset seizures has completed; …
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CLINICAL_TRIALS trial_result · 2016-08-04Clinical Trial Update: Mobile Phone Radiation and Brain Rhythm in Epileptic Patients
A completed clinical trial evaluating whether mobile phone radiation affects brain rhythms in patients with epilepsy.
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CLINICAL_TRIALS trial_result · 2016-07-29Clinical Trial Update: A Safety and Feasibility Study of Enteral LVT vs. Standard of Care for Seizure Control in Pediatric CM [Phase 2]
A Phase 2 safety and feasibility trial assessed enteral Levetiracetam (LVT) versus standard of care for seizure control in pediatric cerebra…
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CLINICAL_TRIALS trial_result · 2016-07-22Clinical Trial Update: A Study of Meditation as a Treatment for Epilepsy [NA]
This document reports a completed clinical trial investigating meditation as a treatment for epilepsy.
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CLINICAL_TRIALS trial_result · 2016-06-14Clinical Trial Update: Analysis of Lateralization of Language in Epileptic Children by Near-infrared Spectroscopy (NIRS) [NA]
This clinical trial update analyzes language lateralization in epileptic children using near-infrared spectroscopy (NIRS). The study status …
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CLINICAL_TRIALS trial_result · 2016-06-07Clinical Trial Update: A Study of the Structure and Function of the Retina in Adult Patients With Refractory Complex Partial Seizures Treated With Vigabatrin (Sabril®) [Phase 4]
Phase 4 trial updating retinal structure and function in adults with refractory complex partial seizures treated with vigabatrin (Sabril); r…
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CLINICAL_TRIALS trial_result · 2016-06-02Clinical Trial Update: Evaluation of the Pharmacokinetics, Safety, and Tolerability of TPM XR as Adjunctive Therapy in Pediatric Subjects With Epilepsy [Phase 1, Phase 2]
Phase 1/2 study evaluating the pharmacokinetics, safety, and tolerability of TPM XR as adjunctive therapy in pediatric epilepsy has complete…
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CLINICAL_TRIALS trial_result · 2016-05-20Clinical Trial Update: Stopping and Preventing Epileptic Seizures Using a Partial Rebreathing Mask [NA]
The University of Aarhus reports completion of a clinical trial evaluating a partial rebreathing mask to stop and prevent epileptic seizures…
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CLINICAL_TRIALS trial_result · 2016-05-19Clinical Trial Update: Effect of Eslicarbazepine Acetate on the Pharmacokinetics of Gliclazide in Healthy Volunteers [Phase 1]
Phase 1 study evaluating the effect of eslicarbazepine acetate on the pharmacokinetics of gliclazide in healthy volunteers to assess potenti…
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CLINICAL_TRIALS trial_result · 2016-05-16Clinical Trial Update: Stress and Seizures - Can a Brief Self-help Book Help? [NA]
A completed clinical trial explored whether a brief self-help book could reduce stress-related seizures in individuals with epilepsy or diss…
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CLINICAL_TRIALS trial_result · 2016-05-10Clinical Trial Update: Does Body Positioning Affect the Yield of Hyperventilation in Routine Pediatric Electroencephalography - EEG Studies? [NA]
This clinical trial update examines whether body positioning affects the yield of hyperventilation in routine pediatric EEG studies for epil…
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CLINICAL_TRIALS trial_result · 2016-04-22Clinical Trial Update: P-glycoprotein Inhibition as Adjunct Treatment for Medically Refractory Epilepsy. [Phase 2, Phase 3]
There is a terminated Phase 2/3 clinical trial evaluating P-glycoprotein inhibitors as adjunct therapy for medically refractory epilepsy, wi…
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CLINICAL_TRIALS trial_result · 2016-04-13Clinical Trial Update: Double-blind, Randomized Study Evaluating the Efficacy and Safety of Brivaracetam in Adults With Partial Onset Seizures [Phase 3]
Phase 3 trial evaluating brivaracetam for adults with partial onset seizures has completed; results posted in 2016.
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CLINICAL_TRIALS trial_result · 2016-04-13Clinical Trial Update: Double-blind, Randomized Study Evaluating the Efficacy and Safety of Brivaracetam in Adults With Partial Onset Seizures [Phase 3]
Phase 3 trial evaluating brivaracetam in adults with partial onset seizures has completed; results posted in 2016.
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CLINICAL_TRIALS trial_result · 2016-04-13Clinical Trial Update: A Double-blind, Randomized Conversion to Monotherapy Study to Evaluate the Efficacy and Safety of Brivaracetam in Subjects (≥ 16 to 75 Years Old) With Partial Onset Seizures [Phase 3]
A Phase 3 double-blind, randomized study evaluating brivaracetam monotherapy for partial-onset seizures in adults was terminated but results…
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CLINICAL_TRIALS trial_result · 2016-04-13Clinical Trial Update: Safety and Tolerability of Intravenous Brivaracetam (Infusion or Bolus) as Adjunctive Antiepileptic Therapy [Phase 3]
A Phase 3 clinical trial assessing the safety and tolerability of intravenous brivaracetam as adjunctive therapy for epilepsy has completed …
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CLINICAL_TRIALS trial_result · 2016-03-07Clinical Trial Update: Women With Epilepsy: Pregnancy Outcomes and Deliveries
This is a completed clinical trial update documenting pregnancy outcomes and deliveries in women with epilepsy.
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CLINICAL_TRIALS trial_result · 2016-03-01Clinical Trial Update: Immunotherapy in Intractable Cryptogenic Epilepsy Patients With Autoimmune Antibody [Phase 4]
Phase 4 clinical trial update evaluating immunotherapy for patients with intractable cryptogenic epilepsy and autoimmune antibodies; current…
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CLINICAL_TRIALS trial_result · 2016-02-23Clinical Trial Update: Trial Comparing the Efficacy and Safety of Lacosamide (LCM) to Carbamazepine Controlled-Release (CBZ-CR); Initial Monotherapy in Epilepsy; Subjects Aged 16 and Older [Phase 3]
Phase 3 trial comparing lacosamide to carbamazepine-CR as initial monotherapy in epilepsy shows results completed with posted findings in 20…
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CLINICAL_TRIALS trial_result · 2016-02-12Clinical Trial Update: Levetiracetam Versus Topiramate as Adjunctive Therapy to Evaluate Efficacy and Safety in Subjects With Refractory Partial Onset Seizures [Phase 4]
A Phase 4 trial compared adjunctive levetiracetam to topiramate in adults with refractory partial-onset seizures. The study is completed and…