Epilepsy
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CLINICAL_TRIALS trial_result · 2017-08-02Clinical Trial Update: Evaluating Long Term Safety of Lacosamide (LCM) to Carbamazepine Controlled-release (CBZ-CR); Initial Monotherapy in Epilepsy Subjects 16 Years and Older [Phase 3]
A Phase 3 clinical trial update evaluating the long-term safety of lacosamide versus carbamazepine controlled-release as initial monotherapy…
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CLINICAL_TRIALS trial_result · 2017-07-19Clinical Trial Update: Equivalence Among Antiepileptic Drug Generic and Brand Products in People With Epilepsy: Single-Dose 6-Period Replicate Design (EQUIGEN Single-Dose Study) [Phase 4]
A Phase 4 clinical trial (EQUIGEN Single-Dose Study) evaluates the bioequivalence of generic and brand antiepileptic drugs in people with ep…
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CLINICAL_TRIALS trial_result · 2017-07-12Clinical Trial Update: TAK-935 Multiple Rising Dose Study in Healthy Participants [Phase 1]
Takeda's TAK-935 Phase 1 multiple rising dose study in healthy participants has completed and results were posted in July 2017.
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CLINICAL_TRIALS trial_result · 2017-07-12Clinical Trial Update: Seizure Detection and Warning System in Epilepsy Patients
The Brain Sentinel seizure detection and warning system clinical trial for epilepsy patients has completed.
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CLINICAL_TRIALS trial_result · 2017-07-12Clinical Trial Update: Sabril for Complex Partial Seizures in Adult Tolerability Study (TS) Patients [Phase 4]
A Phase 4 tolerability study of vigabatrin (Sabril) for complex partial seizures was terminated; results were posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-07-11Clinical Trial Update: Does Memantine Improve Verbal Memory Task Performance in Subjects With Partial Epilepsy and Memory Dysfunction? [NA]
A completed clinical trial assessed memantine for improving verbal memory in individuals with partial epilepsy and memory dysfunction. Resul…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Non-Invasive Seizure Localization in Patients With Medically Refractory Localization Related Epilepsy: Synchronized MEG-EEG Recordings
This completed clinical trial evaluated synchronized MEG-EEG recordings as a non-invasive method to localize seizures in patients with local…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Role of Hormones in Susceptibility to Seizures in Women With Epilepsy
An update on a completed clinical trial investigating how hormones influence seizure susceptibility in women with epilepsy. The study status…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Reducing Seizure Frequency Using Cooling of the Head and Neck [Phase 2]
A Phase 2 clinical trial assessing cooling of the head and neck to reduce seizure frequency in epilepsy has completed.
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Brain Tissue Swelling and Seizure Activity in Inactive Cysticercosis
This completed clinical trial investigated brain swelling and seizure activity associated with inactive cysticercosis. The update highlights…
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CLINICAL_TRIALS trial_result · 2017-06-28Clinical Trial Update: Impact of Neuropsychological Evaluation on Epilepsy Treatment [Phase 2]
A Phase 2 clinical trial from the University of South Florida investigates how neuropsychological evaluation affects epilepsy treatment, but…
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CLINICAL_TRIALS trial_result · 2017-06-28Clinical Trial Update: Topiramate Bioequivalence Study Brazil - Fast [Phase 1]
GlaxoSmithKline conducted a Phase 1 bioequivalence study of topiramate in Brazil, and the trial has completed.
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CLINICAL_TRIALS trial_result · 2017-06-27Clinical Trial Update: Preventing Epilepsy After Traumatic Brain Injury With Topiramate [EARLY_Phase 1]
Phase 1 trial evaluating topiramate to prevent epilepsy after traumatic brain injury was terminated early.
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CLINICAL_TRIALS trial_result · 2017-06-23Clinical Trial Update: Cannabidiol Oral Solution in Pediatric Participants With Treatment-resistant Seizure Disorders [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating cannabidiol oral solution in pediatric participants with treatment-resistant seizure disorders has compl…
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CLINICAL_TRIALS trial_result · 2017-06-20Clinical Trial Update: Bioequivalence Study of 300 mg Gabapentin [Phase 1]
A Phase 1 study evaluating the bioequivalence of 300 mg gabapentin formulations has completed.
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CLINICAL_TRIALS trial_result · 2017-06-09Clinical Trial Update: Efficacy, Tolerability and Adherence of the Modified Atkins Diet on Drug-resistant Epilepsy [NA]
This clinical trial update reports on the efficacy, tolerability, and adherence of the Modified Atkins Diet in individuals with drug-resista…
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CLINICAL_TRIALS trial_result · 2017-06-05Clinical Trial Update: Progesterone vs Placebo Therapy for Women With Epilepsy [Phase 3]
A Phase 3 trial comparing progesterone versus placebo for women with epilepsy has completed; results have been posted.
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CLINICAL_TRIALS trial_result · 2017-06-01Clinical Trial Update: The Bioequivalence Study of Lamotrigine Dispersible/Chewable Tablets 5mg×5 Compared With Lamotrigine Compressed Tablet 25mg in Chinese Healthy Male Subjects [Phase 1]
Phase 1 bioequivalence study comparing lamotrigine dispersible/chewable 5mg×5 with lamotrigine 25mg tablet in healthy Chinese male subjects …
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CLINICAL_TRIALS trial_result · 2017-05-31Clinical Trial Update: Safety and Tolerability of OXC XR as Adjunctive Therapy in Subjects With Refractory Partial Epilepsy [Phase 3]
Phase 3 trial assessing the safety and tolerability of OXC XR as adjunctive therapy in adults with refractory partial epilepsy; results were…
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CLINICAL_TRIALS trial_result · 2017-05-30Clinical Trial Update: Lethargic Depression Study [Phase 3]
The Phase 3 Lethargic Depression Study, sponsored by GlaxoSmithKline, has completed. The study investigated epilepsy and major depressive di…
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CLINICAL_TRIALS trial_result · 2017-05-18Clinical Trial Update: A Conversion Study of Immediate Release (IR) and Modified Release (MR) Forms of Topiramate (TPM) [Phase 1]
This clinical trial update reports the completion of a Phase 1 study comparing immediate-release and modified-release topiramate for epileps…
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CLINICAL_TRIALS trial_result · 2017-05-11Clinical Trial Update: Remegal Different Doses in Patients With Refractory Partial Seizures [Phase 2]
Phase 2 trial evaluating different doses of Remegal in patients with refractory partial seizures has completed.
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CLINICAL_TRIALS trial_result · 2017-05-11Clinical Trial Update: Remegal Fixed Dose as Adjunctive Therapy in Patients With Partial Seizures [Phase 3]
A Phase 3 trial of Remegal fixed-dose as adjunctive therapy for partial seizures has completed under sponsor Valexfarm.
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CLINICAL_TRIALS trial_result · 2017-05-10Clinical Trial Update: The Bioequivalence Study of Lamotrigine Dispersible/Chewable Tablets 100mg Compared With Compressed Tablet 100 mg [Phase 1]
Phase 1 bioequivalence study comparing lamotrigine dispersible/chewable 100 mg with lamotrigine 100 mg compressed tablet completed.
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CLINICAL_TRIALS trial_result · 2017-05-09Clinical Trial Update: Effect of Magnesium Supplementation for Children With Drug Resistant Idiopathic Epilepsy [NA]
A clinical trial evaluating magnesium supplementation for children with drug-resistant idiopathic epilepsy has completed. The snippet does n…