Epilepsy
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-07-10Clinical Trial Update: Detecting Generalized Tonic-Clonic Seizures With a Seizure Detection and Warning System in Epilepsy Patients
Completed clinical trial evaluating Brain Sentinel's Seizure Detection and Warning System for detecting generalized tonic-clonic seizures in…
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CLINICAL_TRIALS trial_result · 2018-07-05Clinical Trial Update: The Role of Serotonin in Seizures
A clinical trial exploring the role of serotonin in seizures conducted by NINDS has been terminated.
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CLINICAL_TRIALS trial_result · 2018-07-05Clinical Trial Update: Brain P-gp and Inflammation in People With Epilepsy
This clinical trial update reports the completion of a study evaluating brain P-glycoprotein and inflammation in people with partial epileps…
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CLINICAL_TRIALS trial_result · 2018-07-05Clinical Trial Update: Brain Infusion of Muscimol to Treat Epilepsy [Phase 1]
A Phase 1 clinical trial evaluating brain infusion of muscimol for epilepsy was terminated.
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CLINICAL_TRIALS trial_result · 2018-07-02Clinical Trial Update: An Open-label Extension Study to Evaluate the Safety and Tolerability of Perampanel (E2007) Administered as an Adjunctive Therapy in Epilepsy Subjects [Phase 3]
An open-label extension study assessed the safety and tolerability of perampanel as an adjunctive therapy for epilepsy; the Phase 3 trial is…
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CLINICAL_TRIALS trial_result · 2018-06-20Clinical Trial Update: STEP: Enhanced Physical Activity in Children and Youth With Epilepsy [NA]
The STEP trial evaluating enhanced physical activity in children and youth with epilepsy has completed. The update does not include results.
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CLINICAL_TRIALS trial_result · 2018-06-19Clinical Trial Update: An Open-label, Single-centre Study Evaluating the Pharmacokinetics of Digoxin Alone and When Administered at Various Doses of Ezogabine/Retigabine in Healthy Adults. The Pharmacokinetics of Ezogabine/Retigabine and the N-acetyl Metabolite of Ezogabine/Retigabine (NAMR) Will Also be Assessed [Phase 1]
This open-label Phase 1 study assessed the pharmacokinetics of digoxin when given with various doses of ezogabine/retigabine in healthy adul…
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CLINICAL_TRIALS trial_result · 2018-06-19Clinical Trial Update: An Open Label, Randomised, Repeat Dose Study to Assess the Pharmacokinetic Performance of Five Ezogabine/Retigabine Modified Release (MR) Formulations at Steady State Compared to the Immediate Release (IR) Formulation. [Phase 1]
This Phase 1 open-label, randomized, repeat-dose study compares five ezogabine/retigabine modified-release formulations to the immediate-rel…
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CLINICAL_TRIALS trial_result · 2018-06-19Clinical Trial Update: Crossover Study to Evaluate the Pharmacokinetics of Ezogabine/Retigabine in Taiwanese Subjects [Phase 1]
A Phase 1 crossover study evaluating the pharmacokinetics of ezogabine/retigabine in Taiwanese subjects has been completed.
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CLINICAL_TRIALS trial_result · 2018-06-19Clinical Trial Update: Effect of Haemodialysis on the Pharmacokinetics of Ezogabine/Retigabine and Its N-acetyl Metabolite [Phase 1]
This completed Phase 1 study assessed the effect of haemodialysis on the pharmacokinetics of ezogabine/retigabine and its N-acetyl metabolit…
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CLINICAL_TRIALS trial_result · 2018-06-06Clinical Trial Update: Open-Label Extension Study of the Phase 3 VRX-RET-E22-302 Double-Blind Trial. 115097 [Phase 3]
Open-label extension study update for a Phase 3 trial investigating a GSK epilepsy program; trial terminated with results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-05-23Clinical Trial Update: Epileptic Potentials During Cardiac Surgery and Association With Postoperative Neurological Outcome
A completed clinical trial assessing epileptic potentials during cardiac surgery and their relationship with postoperative neurological outc…
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CLINICAL_TRIALS trial_result · 2018-05-21Clinical Trial Update: Tele-patient-reported Outcomes (telePRO) in Clinical Practice [NA]
A study evaluating tele-patient-reported outcomes (telePRO) in epilepsy has completed.
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CLINICAL_TRIALS trial_result · 2018-05-14Clinical Trial Update: Radiosurgery or Open Surgery for Epilepsy Trial [NA]
A clinical trial comparing radiosurgery versus open surgery for epilepsy has completed.
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CLINICAL_TRIALS trial_result · 2018-05-09Clinical Trial Update: Clobazam Use in Epilepsia Partialis Continua - Pilot Study [Phase 3]
A Phase 3 pilot trial evaluating clobazam for Epilepsia Partialis Continua has been terminated.
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CLINICAL_TRIALS trial_result · 2018-05-07Clinical Trial Update: Reduction and Prevention of Seizure Occurrence From Exposure to Auditory Stimulation in Individuals With Neurological Handicaps [NA]
A completed clinical trial evaluated whether exposure to auditory stimulation can reduce or prevent seizures in individuals with neurologica…
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CLINICAL_TRIALS trial_result · 2018-04-30Clinical Trial Update: Effect of Yoga on Mood and Quality of Life in Patients With Refractory Epilepsy [NA]
This completed clinical trial evaluated how yoga affects mood and quality of life in patients with refractory epilepsy, including those with…
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CLINICAL_TRIALS trial_result · 2018-04-23Clinical Trial Update: An Open-label, Multinational, Multicenter, Follow-up Study to Evaluate the Long-term Safety and Efficacy of Brivaracetam [Phase 3]
An open-label, multinational Phase 3 follow-up study evaluating the long-term safety and efficacy of brivaracetam in epilepsy; results were …
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CLINICAL_TRIALS trial_result · 2018-04-19Clinical Trial Update: Stress Management Intervention for Living With Epilepsy (SMILE) [NA]
The SMILE trial evaluating a stress management intervention for people with epilepsy has completed.
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CLINICAL_TRIALS trial_result · 2018-04-18Clinical Trial Update: Impact of Polymorphisms of OCT2 and OCTN1 on the Kinetic Disposition of Gabapentin in Patients Undergoing Chronic Use [Phase 4]
Phase 4 trial update examining how OCT2 and OCTN1 polymorphisms influence gabapentin pharmacokinetics in patients on chronic therapy. The st…
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CLINICAL_TRIALS trial_result · 2018-04-05Clinical Trial Update: In Vivo Imaging of Therapeutic Electric Current Flow
Clinical trial update noting the completed study on in vivo imaging of therapeutic electric current flow, with listed conditions including P…
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CLINICAL_TRIALS trial_result · 2018-03-19Clinical Trial Update: Study to Investigate Lacosamide as Add-on Therapy in Subjects ≥4 Years to <17 Years of Age With Partial Onset Seizures [Phase 3]
Phase 3 trial update for lacosamide as add-on therapy in children aged 4 to under 17 with partial onset seizures. The study has completed an…
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CLINICAL_TRIALS trial_result · 2018-03-14Clinical Trial Update: Imaging Neuroinflammation in Epilepsy With Ferumoxytol MRI [NA]
A completed clinical trial (NCT02084303) evaluated using ferumoxytol-enhanced MRI to image neuroinflammation in epilepsy. The trial status i…
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CLINICAL_TRIALS trial_result · 2018-03-14Clinical Trial Update: A Complex Contraception Registry
This clinical trial update reports the completion of a complex contraception registry sponsored by the University of California, San Diego, …
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CLINICAL_TRIALS trial_result · 2018-03-06Clinical Trial Update: The Effect of Anti-epileptic Drugs on Mitochondrial Activity
A completed clinical trial assessing the effect of anti-epileptic drugs on mitochondrial activity in epilepsy.