Epilepsy
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-12-19Clinical Trial Update: Safety and Pharmacokinetics Study of E2007 to Treat Partial and Generalised Seizures in People With Epilepsy [Phase 2]
Phase 2 safety and pharmacokinetics study of E2007 for partial and generalized seizures in epilepsy completed.
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CLINICAL_TRIALS trial_result · 2018-12-07Clinical Trial Update: PRX-00023 Therapy in Localization-Related Epilepsy [Phase 2]
Phase 2 trial update for PRX-00023 in localization-related epilepsy (temporal lobe). Trial status terminated; results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-12-05Clinical Trial Update: This Trial, Evaluating the Long-term Safety and Tolerability of Brivaracetam Will Provide Subjects Suffering From Epilepsy, Who May Have Benefited From Brivaracetam as Adjunctive Treatment, the Opportunity to Receive Open Label Brivaracetam Treatment [Phase 3]
A Phase 3 trial evaluating long-term safety and tolerability of brivaracetam in epilepsy has completed with open-label extension data availa…
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CLINICAL_TRIALS trial_result · 2018-11-27Clinical Trial Update: Study to Evaluate the Safety and Efficacy of USL261 in Patients With Increased Bouts of Seizure Activity in the EMU [Phase 3]
Phase 3 study evaluating USL261 for epilepsy has completed with posted results.
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CLINICAL_TRIALS trial_result · 2018-10-26Clinical Trial Update: Premenstrual Dysphoric Disorder and Antiepileptic Drugs
Clinical trial update related to premenstrual dysphoric disorder and antiepileptic drugs; results completed with results posted.
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CLINICAL_TRIALS trial_result · 2018-10-16Clinical Trial Update: Eslicarbazepine Acetate (BIA 2-093) as Monotherapy in Patients With Newly Diagnosed Partial-onset Seizures [Phase 3]
Phase 3 trial update on eslicarbazepine acetate as monotherapy for newly diagnosed partial-onset seizures.
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CLINICAL_TRIALS trial_result · 2018-10-16Clinical Trial Update: Bioavailability, Safety and Tolerability of Diazepam Nasal Spray Versus Diazepam Rectal Gel (Diastat®) [Phase 2]
Phase 2 trial comparing diazepam nasal spray to diazepam rectal gel (Diastat) for bioavailability, safety, and tolerability in refractory ep…
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CLINICAL_TRIALS trial_result · 2018-10-11Clinical Trial Update: Comparison Between Lorazepam, Clonazepam and Clonazepam + Fosphenytoin for the Treatment of Out-of-hospital Generalized Status Epilepticus [Phase 3]
Phase 3 trial comparing lorazepam, clonazepam, and clonazepam plus fosphenytoin for out-of-hospital generalized status epilepticus has compl…
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CLINICAL_TRIALS trial_result · 2018-10-01Clinical Trial Update: Monotherapy With Levetiracetam in Patients Suffering From Epilepsy. [Phase 3]
A Phase 3 monotherapy trial of levetiracetam in epilepsy patients has completed, with results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-09-13Clinical Trial Update: Transcutaneous Vagal Nerve Stimulation: Influence on miRNA, Inflammation, Cerebral Resting State and Gastric Motility [Phase 1, Phase 2]
Clinical trial update on transcutaneous vagal nerve stimulation assessing miRNA, inflammation, cerebral resting state, and gastric motility …
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CLINICAL_TRIALS trial_result · 2018-09-11Clinical Trial Update: An Open-label Extension Study to Investigate Possible Drug-drug Interactions Between Clobazam and Cannabidiol [Phase 2]
An open-label Phase 2 extension study evaluated possible drug-drug interactions between clobazam and cannabidiol in epilepsy patients; compl…
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CLINICAL_TRIALS trial_result · 2018-08-29Clinical Trial Update: A Long-term Extension Study of E2007 in Patients With Refractory Partial Seizures Uncontrolled With Other Anti-Epileptic Drugs (AEDs) [Phase 2]
Long-term extension study of E2007 in patients with refractory partial seizures completed; results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-08-23Clinical Trial Update: A Randomized Controlled Trial to Investigate Possible Drug-drug Interactions Between Clobazam and Cannabidiol [Phase 2]
Phase 2 randomized trial assessing potential drug-drug interactions between clobazam and cannabidiol in epilepsy; results posted after compl…
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CLINICAL_TRIALS trial_result · 2018-08-22Clinical Trial Update: A Dose-ranging Study With Brivaracetam in Patients From 16 to 65 Years With Refractory Partial Onset Seizures. [Phase 2]
Phase 2 dose-ranging study of brivaracetam in patients with refractory partial onset seizures completed; results posted.
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CLINICAL_TRIALS trial_result · 2018-08-07Clinical Trial Update: Cognitive Effects of Treatment of Interictal Discharges [NA]
Clinical trial assessing cognitive effects of treatment of interictal discharges in epilepsy has completed and results posted.
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CLINICAL_TRIALS trial_result · 2018-07-30Clinical Trial Update: An Open-Label, Safety and Tolerability Study of Chronic Intermittent Use of Diazepam Nasal Spray. [Phase 2]
This open-label Phase 2 study assessed the safety and tolerability of chronic intermittent diazepam nasal spray in epilepsy, and the trial w…
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CLINICAL_TRIALS trial_result · 2018-07-27Clinical Trial Update: A Study to Investigate the Efficacy and Safety of Cannabidiol (GWP42003-P; CBD) as Adjunctive Treatment for Seizures Associated With Lennox-Gastaut Syndrome in Children and Adults [Phase 3]
Phase 3 clinical trial evaluating CBD as adjunctive treatment for seizures in Lennox-Gastaut syndrome; trial completed with results posted i…
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CLINICAL_TRIALS trial_result · 2018-07-26Clinical Trial Update: Cannabidiol Oral Solution as an Adjunctive Treatment for Treatment-resistant Seizure Disorder [Phase 3]
This clinical trial update reports the results of a Phase 3 study of cannabidiol oral solution as an adjunctive treatment for treatment-resi…
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CLINICAL_TRIALS trial_result · 2018-07-23Clinical Trial Update: Vagus Nerve Stimulation Titration Protocol to Improve Tolerance and Accelerate Adaptation
A completed clinical trial examining a titration protocol for the vagus nerve stimulator to improve tolerability and speed adaptation in epi…
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CLINICAL_TRIALS trial_result · 2018-07-20Clinical Trial Update: Antiepileptic Efficacy Study of GWP42003-P in Children and Young Adults With Dravet Syndrome (GWPCARE1) [Phase 3]
Phase 3 trial update on GWP42003-P in children and young adults with Dravet syndrome. Completed with results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-07-20Clinical Trial Update: Evaluation of Stress Sensitivity and Hyperemotivity in Epilepsy Compared to and a Group of Healthy Volunteers [NA]
This clinical trial update describes a study evaluating stress sensitivity and hyperemotivity in people with epilepsy compared to healthy vo…
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CLINICAL_TRIALS trial_result · 2018-07-19Clinical Trial Update: A Dose-ranging Pharmacokinetics and Safety Study of GWP42003-P in Children With Dravet Syndrome (GWPCARE1) [Phase 2]
Phase 2 dose-ranging pharmacokinetics and safety study of GWP42003-P in children with Dravet syndrome completed; results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-07-18Clinical Trial Update: A Pilot Study of Creative Arts Interventions for Neurology Inpatients [NA]
Completed pilot trial assessing the feasibility and potential effects of creative arts interventions for neurology inpatients, including ind…
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CLINICAL_TRIALS trial_result · 2018-07-17Clinical Trial Update: Eslicarbazepine Acetate Monotherapy Long Term Study [Phase 3]
A Phase 3 long-term monotherapy trial of eslicarbazepine acetate in epilepsy has completed, with results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-07-12Clinical Trial Update: Investigation of Human Epileptic Networks by fMRI [NA]
This clinical trial update reports that the investigation of human epileptic networks by functional MRI has completed.