Endothelial Dysfunction
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: Study to Assess Safety and Tolerability of Multiple Doses of EO2002 [Phase 1]
Phase 1 study to assess safety and tolerability of multiple doses of EO2002 in patients with corneal edema and related endothelial diseases;…
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CLINICAL_TRIALS withdrawal · 2025-12-02Clinical Trial Update: Effects of Nitric Oxide on the Endothelium During Hemolysis. [Phase 2]
A Phase 2 clinical trial evaluating the effects of inhaled nitric oxide on the endothelium during intravascular hemolysis has been withdrawn…
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CLINICAL_TRIALS withdrawal · 2025-12-02Clinical Trial Update: Effects of Prolonged Delivery of Nitric Oxide Gas on Plasma Reduction-Oxidation Reactions in Cardiac Surgical Patients [Phase 2]
A Phase 2 clinical trial evaluating prolonged inhaled nitric oxide gas and its effects on plasma redox reactions in cardiac surgical patient…
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: Testosterone Deficiency and Endothelial Dysfunction After Spinal Cord Injury
Clinical trial update on testosterone deficiency and endothelial dysfunction after spinal cord injury. The study is currently recruiting.
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: Wild Blueberries and Cardiovascular Health in Middle-aged/Older Men and Postmenopausal Women [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial from Colorado State University is evaluating whether wild blueberries can influence cardiovascular health i…
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CLINICAL_TRIALS research · 2025-11-14Clinical Trial Update: Role of Endothelial Dysfunction on Exercise Pressor Reflex in Type 2 Diabetes [NA]
This clinical trial update examines how endothelial dysfunction influences the exercise pressor reflex in individuals with Type 2 diabetes, …
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CLINICAL_TRIALS research · 2025-11-14Clinical Trial Update: Endothelial Dysfunction After SCI
Craig Hospital is conducting a clinical trial to study endothelial dysfunction in patients with spinal cord injury, currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-11-12Clinical Trial Update: Fisetin to Improve Vascular Function in Older Adults [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating fisetin to improve vascular function in older adults with aging-related endothelial dysfunction and…
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CLINICAL_TRIALS withdrawal · 2025-11-06Clinical Trial Update: Determining the Association of Microvascular Disease as Assessed by PET and Graft Injury by Donor Derived Cell Free DNA
A clinical trial investigating the association between microvascular disease by PET and graft injury via donor-derived cell-free DNA has bee…
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CLINICAL_TRIALS research · 2025-09-25Clinical Trial Update: Effect of Propionic Acid Supplementation on Endothelial Function [NA]
A clinical trial is evaluating whether propionic acid supplementation improves endothelial function in cardiovascular disease. The study sta…
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CLINICAL_TRIALS research · 2025-09-23Clinical Trial Update: Ischemic Conditioning to Promote Microvascular Resiliency in Frail Individuals [Phase 2]
A Phase 2 clinical trial update for ischemic conditioning aimed at promoting microvascular resiliency in frail individuals, currently recrui…
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CLINICAL_TRIALS research · 2025-09-12Clinical Trial Update: NightWare and Cardiovascular Health in Veterans With PTSD [NA]
This clinical trial update notes ongoing recruitment for a study evaluating the NightWare digital therapeutic device and its impact on cardi…
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CLINICAL_TRIALS trial_result · 2025-09-10Clinical Trial Update: Feasibility of Digital Thermal Monitoring to Assess Endothelium-Dependent Vasodilation in Patients Undergoing Hematopoietic Cell Transplantation (HCT) [NA]
The update notes that the feasibility trial using digital thermal monitoring to assess endothelium-dependent vasodilation in hematopoietic c…
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CLINICAL_TRIALS trial_result · 2025-09-08Clinical Trial Update: Investigation of the Etiology of Hypertension and Endothelial Damage in Patients With Cytochrome P450 Oxidoreductase Deficiency
A completed clinical trial investigating the causes of hypertension and endothelial damage in individuals with cytochrome P450 oxidoreductas…
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CLINICAL_TRIALS research · 2025-08-22Clinical Trial Update: Infusion of Prostacyclin vs Placebo for 72-hours in Mechanically Ventilated Patients With Acute Respiratory Failure [Phase 2]
Phase 2 clinical trial evaluating 72-hour prostacyclin infusion versus placebo in mechanically ventilated patients with acute respiratory fa…
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CLINICAL_TRIALS research · 2025-08-06Clinical Trial Update: Investigation of the Effects of Dietary Nitrate and Sex on COVID-19 Vaccine Induced Vascular Dysfunction in Healthy Men and Women (DiNOVasc-COVID-19) [Phase 1]
A Phase 1 study assessing whether dietary nitrate and sex affect vascular dysfunction induced by COVID-19 vaccination in healthy adults.
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CLINICAL_TRIALS research · 2025-07-15Clinical Trial Update: Impaired Endothelial Integrity in Patients With Embolic Stroke of Undetermined Source (ESUS)
A clinical trial update from the University of Athens notes impaired endothelial integrity in patients with Embolic Stroke of Undetermined S…
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CLINICAL_TRIALS trial_result · 2025-07-11Clinical Trial Update: Intermittent Hypoxic-hyperoxic Training in Patients With Cardiovascular Pathology After COVID-19 Infection. [NA]
This clinical trial evaluated intermittent hypoxic-hyperoxic training in patients with cardiovascular pathology after COVID-19 infection, an…
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CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: SGC Stimulation, Perioperative Vascular Reactivity, and Organ Injury in Cardiac Surgery [Phase 4]
Phase 4 clinical trial update from Vanderbilt University Medical Center evaluating soluble guanylate cyclase stimulation to improve perioper…
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CLINICAL_TRIALS trial_result · 2025-06-29Clinical Trial Update: Effect of Plasma Ceramides on Peripheral Vascular Function [NA]
Completed clinical trial assessing whether plasma ceramides affect peripheral vascular function.
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CLINICAL_TRIALS trial_result · 2025-06-29Clinical Trial Update: COronary Microcirculation and Troponin Elevation in Septic Shock
An update on a completed clinical trial investigating coronary microcirculation and troponin elevation in septic shock has been released. Th…
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CLINICAL_TRIALS trial_result · 2025-06-15Clinical Trial Update: Cardiometabolic Benefits of Potatoes Mediated Along the Gut-Vessel Axis in Adults With Metabolic Syndrome [NA]
A completed clinical trial investigated cardiometabolic benefits of potatoes mediated along the gut–vessel axis in adults with metabolic syn…
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CLINICAL_TRIALS trial_result · 2025-06-15Clinical Trial Update: Myoglobin Removal With CytoSorb in Rhabdomyolysis
Completed clinical trial evaluating CytoSorb hemoadsorption for myoglobin removal in rhabdomyolysis patients with acute kidney injury.
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CLINICAL_TRIALS research · 2025-06-13Clinical Trial Update: MANATEE-T1D: Metformin ANd AutomaTEd Insulin Delivery System Effects on Renal Vascular Resistance, Insulin Sensitivity, and Cardiometabolic Function in Youth With Type 1 Diabetes [Phase 1]
Phase 1 MANATEE-T1D trial assessing metformin with an automated insulin delivery system on renal vascular resistance, insulin sensitivity, a…
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CLINICAL_TRIALS research · 2025-06-13Clinical Trial Update: NightWare and Cardiovascular Health in Women With PTSD [NA]
Registration update for a NightWare trial examining cardiovascular health outcomes in women with post-traumatic stress disorder; study statu…