Endometrial Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: GEN1047 for Solid Tumors - First in Human (FIH) Trial [Phase 1, Phase 2]
Genmab's GEN1047 first-in-human Phase 1/2 trial in solid tumors has been terminated, with indications including breast cancer, endometrial c…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Molecular and ctDNA Characterization of High-Risk Endometrial Cancer
A Mayo Clinic-backed clinical trial is investigating molecular and ctDNA characterization in high-risk endometrial cancer to improve underst…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Testing the Addition of the AKT Inhibitor, Ipatasertib, to Treatment With the Hormonal Agent Megestrol Acetate for Recurrent or Metastatic Endometrial Cancers [Phase 1, Phase 2]
Clinical trial update exploring addition of the AKT inhibitor ipatasertib to megestrol acetate for recurrent or metastatic endometrial cance…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to the Usual Radiation Treatment for Newly Diagnosed Early Stage High Intermediate Risk Endometrial Cancer [Phase 3]
This Phase 3 trial is evaluating adding pembrolizumab to standard radiation therapy for newly diagnosed early-stage high-intermediate risk e…
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CLINICAL_TRIALS other · 2026-04-13Clinical Trial Update: Maintenance With Selinexor/Placebo After Combination Chemotherapy in Participants With Endometrial Cancer [SIENDO] [Phase 3]
Clinical trial SIENDO (NCT03555422) evaluates maintenance selinexor vs placebo following combination chemotherapy in endometrial cancer; the…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Inavolisib for PIK3CA Mutated Advanced Endometrial Cancer: MITO END-4 [Phase 2]
MITO END-4 is a Phase 2 trial evaluating Inavolisib for PIK3CA-mutated advanced endometrial cancer; the study is not yet recruiting.
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study of Giredestrant in Participants With Grade 1 Endometrial Cancer [Phase 2]
This clinical trial update reports a phase 2 study of giredestrant in participants with grade 1 endometrial cancer; the trial is currently a…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Testing Different Amounts of the Combination of Drugs M1774 and ZEN-3694 for the Treatment of Recurrent Ovarian and Endometrial Cancer [Phase 1]
Phase 1 clinical trial assessing different dosing amounts of the drug combination M1774 and ZEN-3694 for recurrent ovarian and endometrial c…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Risk Evaluation and Screening to Tailor Prevention and Reduce the Incidence of Endometrial Cancer [Phase 4]
Phase 4 trial evaluating risk evaluation and screening to tailor prevention and reduce the incidence of endometrial cancer has completed.
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Puxitatug Samrotecan (AZD8205) Monotherapy vs Chemotherapy in B7-H4-selected Endometrial Cancer (Bluestar-Endometrial01) [Phase 3]
Phase 3 trial evaluating Puxitatug Samrotecan (AZD8205) as monotherapy versus chemotherapy in B7-H4-selected endometrial cancer is currently…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Testing the Combination of APG-1252 (Pelcitoclax) and Cobimetinib in Recurrent Ovarian and Endometrial Cancers [Phase 1]
This is a Phase 1 clinical trial update evaluating the combination of APG-1252 (Pelcitoclax) and cobimetinib in recurrent and advanced ovari…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Prospective Randomised Phase II Trial Evaluating Adjuvant Pelvic Radiotherapy Using Either IMRT or 3-Dimensional Planning for Endometrial Cancer. ICORG 09-06 [Phase 2]
A phase II randomized trial comparing IMRT versus 3D pelvic radiotherapy planning for adjuvant treatment of endometrial cancer was terminate…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: A Phase 1 Study of CTIM-76 in Patients With Recurring Ovarian Cancer and Other Advanced Solid Tumors [Phase 1]
Context Therapeutics reports an ongoing Phase 1 study of CTIM-76 in platinum-resistant ovarian cancer and other advanced solid tumors, with …
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Veliparib, Paclitaxel, and Carboplatin in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery and Liver or Kidney Dysfunction [Phase 1]
Phase 1 trial evaluating veliparib, paclitaxel, and carboplatin in patients with various metastatic or unresectable solid tumors and liver o…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Chemotherapy or Observation in Stage I-II Intermediate or High Risk Endometrial Cancer [Phase 2]
A Phase 2 trial evaluating chemotherapy versus observation for stage I–II intermediate or high-risk endometrial cancer. The study is current…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study of a Weight Loss Intervention in People With Endometrial Cancer [EARLY_Phase 1]
This entry reports an ongoing EARLY_PHASE1 clinical trial at Memorial Sloan Kettering Cancer Center to evaluate a weight loss intervention i…
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CLINICAL_TRIALS trial_result · 2026-04-09Clinical Trial Update: Safety, PK and Efficacy of AI-061 in Advanced Solid Tumors [Phase 1]
Phase 1 update reporting safety, pharmacokinetics, and preliminary efficacy data for AI-061 in advanced solid tumors across multiple indicat…
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CLINICAL_TRIALS trial_result · 2026-04-09Clinical Trial Update: A Phase 1 Study of the Safety and Tolerability of CTX-10726 [Phase 1]
Phase 1 study update on the safety and tolerability of CTX-10726, currently recruiting across gastroesophageal cancer, hepatocellular carcin…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: A Phase 2 Study of T-DXd in Patients With Selected HER2 Expressing Tumors [Phase 2]
A Phase 2 clinical trial update for trastuzumab deruxtecan (Enhertu) in HER2-expressing tumors, including bladder, biliary tract, cervical, …
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CLINICAL_TRIALS trial_result · 2026-04-09Clinical Trial Update: A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors [Phase 2]
Jazz Pharmaceuticals is conducting a Phase 2 trial of Zanidatamab in HER2-expressing tumors across multiple cancers. The study is currently …
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Pembrolizumab, Lenvatinib and IL-15 Superagonist N-803 in Combination With HER2 Targeting Autologous Dendritic Cell (AdHER2DC) Vaccine in Participants With Advanced or Metastatic Endometrial Cancer [Phase 1, Phase 2]
This clinical trial is investigating a combination therapy of pembrolizumab, lenvatinib, and the IL-15 superagonist N-803 with a HER2-target…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: EIK1005-002: A Clinical Research Study Evaluating EIK1005, a Werner Helicase Inhibitor, as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors Including Microsatellite Instability High (MSI-H) Tumors [Phase 1, Phase 2]
This clinical trials update notes ongoing Phase 1/2 studies of EIK1005, a Werner helicase inhibitor, as monotherapy and in combination with …
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: ESPERANZA: External Control Arm Study for T-DXd for Patients With HER2 IHC3+ Solid Tumors
ESPERANZA is an external control arm study of trastuzumab deruxtecan (T-DXd) for patients with HER2 IHC3+ solid tumors, sponsored by AstraZe…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer [Phase 3]
This is a Phase III clinical trial evaluating trastuzumab deruxtecan with either rilvegostomig or pembrolizumab as first-line therapy for HE…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Plant-Based Nutrition for Breast or Endometrial Cancer [NA]
A clinical trial investigating plant-based nutrition as an intervention for metastatic breast cancer and stage IV endometrial cancer is list…