Endometrial Cancer

• CLINICAL_TRIALS research · 2025-04-15
  Clinical Trial Update: Postoperative Hypofractionated Radiation in Cervical and Endometrial Tumours: Phase II Study [NA]

  This document provides an update on an ongoing Phase II clinical trial evaluating postoperative hypofractionated radiation therapy for cervi…

• CLINICAL_TRIALS research · 2025-04-15
  Clinical Trial Update: TH1902 in Patients With Advanced Solid Tumors [Phase 1]

  This is a Phase 1 clinical trial update for TH1902 in patients with advanced solid tumors. The study is currently active/not recruiting and …

• CLINICAL_TRIALS trial_result · 2025-04-08
  Clinical Trial Update: QL1706-Based Therapy Post-PD-1/L1 Failure in Advanced Endometrial Cancer [Phase 2]

  Phase 2 clinical trial evaluating QL1706-based therapy in advanced endometrial cancer patients who progressed after PD-1/PD-L1 therapy; curr…

• CLINICAL_TRIALS research · 2025-04-06
  Clinical Trial Update: Gonadotropin-releasing Hormone Agonist (GnRHa) Plus Letrozole In Young Women With Early Endometrial Cancer [Phase 2]

  Phase 2 clinical trial evaluating the combination of a gonadotropin-releasing hormone agonist (GnRHa) and letrozole in young women with earl…

• CLINICAL_TRIALS trial_result · 2025-04-04
  Clinical Trial Update: Study of XB002 in Subjects With Solid Tumors (JEWEL-101) [Phase 1]

  JEWEL-101 is a Phase 1 trial of XB002 in patients with solid tumors, covering multiple indications. The study has completed.

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• CLINICAL_TRIALS research · 2025-04-03
  Clinical Trial Update: First-line Carboplatin and Paclitaxel in Combination With Pembrolizumab, Followed by Maintenance Pembrolizumab With or Without Nesuparib, in Patients With Newly Diagnosed Advanced or Recurrent MMR-proficient (pMMR) Endometrial Cancer [Phase 2]

  Phase 2 clinical trial evaluating first-line carboplatin and paclitaxel with pembrolizumab, followed by maintenance pembrolizumab with or wi…

• CLINICAL_TRIALS research · 2025-04-03
  Clinical Trial Update: Application-Assisted Weight Management in Endometrial Cancer Fertility Preservation [NA]

  A clinical trial listing for application-assisted weight management aimed at fertility preservation in women with endometrial cancer; the st…

• CLINICAL_TRIALS trial_result · 2025-04-02
  Clinical Trial Update: TT-10 (PORT-6) and TT-4 (PORT-7) as Single Agents and in Combination in Subjects With Advanced Selected Solid Tumors [Phase 1, Phase 2]

  Clinical trial update for TT-10 and TT-4 (Portage Biotech) exploring single-agent and combination therapy in advanced solid tumors, with rec…

• CLINICAL_TRIALS research · 2025-04-01
  Clinical Trial Update: A Phase I Clinical Trial of CAR-T Cells for Advanced Gynecological Solid Tumors [NA]

  Phase I clinical trial evaluating CAR-T cell therapy for advanced gynecologic solid tumors is currently recruiting.

• CLINICAL_TRIALS withdrawal · 2025-04-01
  Clinical Trial Update: Efficacy and Safety Study of Lurbinectedin and Dostarlimab in Cancer Patients: Protocol VHIO21001 - LiDer [Phase 1, Phase 2]

  The LiDer protocol study of lurbinectedin and dostarlimab in cancer patients has been withdrawn, with endometrial cancer as the specified co…

• CLINICAL_TRIALS research · 2025-04-01
  Clinical Trial Update: PROfiling Based Endometrial Cancer Adjuvant Therapy [NA]

  A clinical trial evaluating profiling-based adjuvant therapy for endometrial cancer is currently recruiting for stage I and stage II disease…

• CLINICAL_TRIALS trial_result · 2025-03-30
  Clinical Trial Update: Adipocytokines in Endometrial Cancer

  A completed clinical trial from the University of Surrey investigated adipocytokines in endometrial cancer with obesity as a related conditi…

• CLINICAL_TRIALS trial_result · 2025-03-28
  Clinical Trial Update: Evaluation of Carboplatin/Paclitaxel/Bevacizumab in the Treatment of Advanced Stage Endometrial Carcinoma [Phase 2]

  Phase 2 clinical trial evaluating the combination of carboplatin, paclitaxel, and bevacizumab in advanced endometrial cancer; the study stat…

• CLINICAL_TRIALS trial_result · 2025-03-28
  Clinical Trial Update: Feasibility of a Patient Directed Tool to Assess Heart Health Among Endometrial Cancer Survivors [NA]

  A completed clinical trial assessing the feasibility of a patient-directed tool to evaluate heart health in endometrial cancer survivors, wi…

• CLINICAL_TRIALS trial_result · 2025-03-28
  Clinical Trial Update: Bevacizumab and/or Niraparib in Patients With Recurrent Endometrial and/or Ovarian Cancer With ARID1A Mutation [Phase 2]

  Phase 2 trial evaluating bevacizumab and/or niraparib in patients with recurrent endometrial and/or ovarian cancer harboring ARID1A mutation…

• CLINICAL_TRIALS research · 2025-03-28
  Clinical Trial Update: Frequency of Endometrial Cancer Precursors Associated with Lynch Syndrome

  This completed clinical trial investigated how frequently precursors to endometrial cancer occur in individuals with Lynch syndrome.

• CLINICAL_TRIALS research · 2025-03-28
  Clinical Trial Update: Use of an Intrauterine Manipulator and Its Correlation with Positive Peritoneal Cytology in Early Stage Endometrial Cancers [NA]

  The clinical trial examines whether the use of an intrauterine manipulator influences peritoneal cytology in early-stage endometrial cancer,…

• CLINICAL_TRIALS withdrawal · 2025-03-28
  Clinical Trial Update: Endometrial Cancer Recurrence in Patients Taking Metformin

  The clinical trial investigating metformin in patients with recurrent endometrial cancer has been withdrawn.

• CLINICAL_TRIALS trial_result · 2025-03-26
  Clinical Trial Update: Implementing Enhanced Recovery After Surgery (ERAS) Pathways In Major Gynecologic Oncology Operations In Greece [NA]

  A completed clinical trial conducted in Greece assessed the implementation of Enhanced Recovery After Surgery pathways in major gynecologic …

• CLINICAL_TRIALS trial_result · 2025-03-26
  Clinical Trial Update: A Study of RGX-104 in Patients With Advanced Lung & Endometrial Cancer [Phase 1]

  Phase 1 study of RGX-104 in patients with advanced lung and endometrial cancer has completed.

• CLINICAL_TRIALS research · 2025-03-25
  Clinical Trial Update: Assessment of the Effectiveness of the Metabolomic Approach in Screening for Endometrial Cancer

  A recruiting clinical trial is evaluating the effectiveness of a metabolomic approach to screen for endometrial cancer.

• CLINICAL_TRIALS trial_result · 2025-03-20
  Clinical Trial Update: Efficacy Assessment of Lenvatinib Associated with Pembrolizumab in Metastatic Endometrial Cancer: a French Multicentric Retrospective Early Access Program-based Study

  This document reports on a retrospective French multicenter study assessing the efficacy of combining lenvatinib with pembrolizumab in metas…

• CLINICAL_TRIALS research · 2025-03-20
  Clinical Trial Update: Comparison of Transvaginal Paracervical and Transperitoneal Approaches in Lymphadenectomy During v-NOTES Surgery for Patients Diagnosed With Endometrial Cancer [NA]

  Clinical trial update describing a study comparing transvaginal paracervical versus transperitoneal lymphadenectomy approaches during v-NOTE…

• CLINICAL_TRIALS research · 2025-03-20
  Clinical Trial Update: Lipid Mediators & Cancer: Montelukast, SPM, and Almonds [EARLY_Phase 1]

  This early Phase 1 clinical trial from the University of South Florida investigates montelukast, specialized pro-resolving mediators, and al…

• CLINICAL_TRIALS trial_result · 2025-03-19
  Clinical Trial Update: Enzalutamide, Carboplatin, and Paclitaxel in Treating Patients With Stage III-IV or Recurrent Endometrioid Endometrial Cancer [Phase 2]

  Phase 2 trial evaluating enzalutamide in combination with carboplatin and paclitaxel for stage III-IV or recurrent endometrioid endometrial …