Endometrial Cancer
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CLINICAL_TRIALS trial_result · 2025-12-29Clinical Trial Update: Comparison Between High and Low Level Para-aortic Lymphadenectomy in High and Intermediate Risk Endometrial Carcinoma [NA]
The clinical trial comparing high- versus low-level para-aortic lymphadenectomy in high- and intermediate-risk endometrial cancer has comple…
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CLINICAL_TRIALS research · 2025-12-29Clinical Trial Update: Study of Pelvic Hypofractionated Radiotherapy in Endometrial Cancer [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating pelvic hypofractionated radiotherapy for endometrial cancer is currently recruiting.
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CLINICAL_TRIALS research · 2025-12-26Clinical Trial Update: Observational Basket Trial to Collect Tissue to Develop and Train a Live Tumor Diagnostic Platform
An observational basket trial sponsored by Elephas aims to collect tissue to develop and train a live tumor diagnostic platform across multi…
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: Sapanisertib and Serabelisib (PIKTOR) With Paclitaxel and a Substudy With an Insulin-Suppressing Diet in Patients With Advanced/Recurrent Endometrial Cancer [Phase 2]
A Phase 2 clinical trial is evaluating the combination of Sapanisertib and Serabelisib with Paclitaxel, plus a substudy of an insulin-suppre…
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CLINICAL_TRIALS trial_result · 2025-12-23Clinical Trial Update: Durvalumab With or Without Olaparib as Maintenance Therapy After First-Line Treatment of Advanced and Recurrent Endometrial Cancer [Phase 3]
Phase 3 trial evaluating durvalumab with or without olaparib as maintenance therapy after first-line treatment for advanced or recurrent end…
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CLINICAL_TRIALS trial_result · 2025-12-23Clinical Trial Update: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Efficacy and Indications of RP903 [Phase 1]
Phase 1 study of RP903 conducted by Risen (Suzhou) Pharma Tech Co., Ltd. has completed, evaluating safety, tolerability, pharmacokinetics, e…
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CLINICAL_TRIALS trial_result · 2025-12-23Clinical Trial Update: Prognostic Role of molEcular classiFication in Fertility-sparing treAtment of Endometrial canCEr
This clinical trial update examines the prognostic role of molecular classification in fertility-sparing treatment of endometrial cancer. Th…
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CLINICAL_TRIALS research · 2025-12-23Clinical Trial Update: Cervical Cytology DNA Methylation for Endometrial Lesion Screening and Follow-up
This entry describes a planned clinical trial evaluating cervical cytology DNA methylation as a screening and follow-up tool for endometrial…
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CLINICAL_TRIALS research · 2025-12-22Clinical Trial Update: A Study of Dostarlimab in Combination With Carboplatin-paclitaxel in Chinese Participants With Primary Advanced or Recurrent Endometrial Cancer (EC) [Phase 2]
A Phase 2 study evaluating dostarlimab in combination with carboplatin and paclitaxel in Chinese participants with primary advanced or recur…
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CLINICAL_TRIALS research · 2025-12-22Clinical Trial Update: Skeletal Muscle Energy Metabolism in Women With Weight Loss and Ovarian and/or Endometrial Cancer With Weight Loss [NA]
ClinicalTrials.gov update for NCT03027479, a study on skeletal muscle energy metabolism in women with weight loss and ovarian and/or endomet…
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CLINICAL_TRIALS research · 2025-12-19Clinical Trial Update: Clinical Trial Evaluating the Activity of Zanidatamab for the Treatment of Patients With Solid Tumors With an Alteration of the HER2 Gene. [Phase 2]
A Phase 2 clinical trial is evaluating zanidatamab for solid tumors with HER2 gene alterations across multiple indications and is currently …
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CLINICAL_TRIALS research · 2025-12-19Clinical Trial Update: Targeting Inflammation for Endometrial Cancer Prevention
Mayo Clinic is conducting a trial exploring inflammation-targeting strategies for preventing endometrial cancer; the study is currently acti…
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CLINICAL_TRIALS trial_result · 2025-12-18Clinical Trial Update: Impact of Adjuvant Chemotherapy on the Quality of Life of Patients Treated for Stage II / III Endometrial Cancer [NA]
A completed clinical trial assessing how adjuvant chemotherapy affects quality of life in patients with stage II/III endometrial cancer, wit…
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: ctDNA Testing to Inform Standard-of-Care Treatment Decisions in People With Endometrial Cancer [NA]
This entry describes an ongoing clinical trial evaluating circulating tumor DNA testing to guide standard-of-care treatment decisions for en…
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CLINICAL_TRIALS trial_result · 2025-12-18Clinical Trial Update: Adjuvant Hypofractionated Whole Pelvis Radiation Therapy in Endometrial Cancer [NA]
The trial evaluating adjuvant hypofractionated whole pelvis radiation therapy for endometrial cancer has completed.
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Image-Guided Gynecologic Brachytherapy [NA]
A recruiting clinical trial is investigating image-guided gynecologic brachytherapy across cervical, endometrial (uterine), vaginal, vulvar,…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Phase 1 Study Evaluating the Safety and PK of ADU-1805 in Advanced Solid Tumors [Phase 1]
Clinical trial update for a Phase 1 study evaluating the safety and pharmacokinetics of ADU-1805 in adults with advanced solid tumors; the s…
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: A Phase 1 Study of LNCB74 in Advanced Solid Tumors [Phase 1]
Status update for a Phase 1 study of the investigational agent LNCB74 in patients with various advanced solid tumors, including ovarian, bre…
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: Activity and Cancer Survivorship Exercise Pilot [NA]
Update on the Activity and Cancer Survivorship Exercise Pilot trial for endometrial cancer; the study is active but not currently recruiting…
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: Letrozole as Maintenance Therapy for Post-surgical Endometrial Cancer Patients With NSMP [Phase 2, Phase 3]
Clinical trial update indicating termination of a Phase 2/Phase 3 trial of letrozole as maintenance therapy for endometrial cancer with NSMP…
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FDA approval · 2025-12-12FDA Approved: MEDROXYPROGESTERONE ACETATE — Supplemental Application (Prasco Laboratories)
The FDA approved a supplemental application for Medroxyprogesterone acetate from Prasco Laboratories, resulting in labeling changes associat…
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CLINICAL_TRIALS research · 2025-12-12Clinical Trial Update: CYTALUX for Intraoperative Imaging of Patients With Endometrial Cancer [EARLY_Phase 1]
This clinical trial update notes that an early-phase study is recruiting to evaluate CYTALUX (pafolacianine) injection for intraoperative ne…
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CLINICAL_TRIALS research · 2025-12-11Clinical Trial Update: Zanzalintinib in Combination With Paclitaxel in Recurrent High Grade Uterine Cancer [Phase 1]
A Phase 1 clinical trial is evaluating zanzalintinib in combination with paclitaxel for recurrent high-grade uterine cancer, and the study i…
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CLINICAL_TRIALS trial_result · 2025-12-10Clinical Trial Update: Safety and Efficacy of Retifanlimab (INCMGA00012) Alone or in Combination With Other Therapies in Participants With Advanced or Metastatic Endometrial Cancer Who Have Progressed on or After Platinum-based Chemotherapy. [Phase 2]
Phase 2 clinical trial update on retifanlimab, alone or in combination with other therapies, for advanced or metastatic endometrial cancer a…
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: Efficacy and Safety of a Repurposed Drug Added to the Combination of Len Plus Pem in Advanced Endometrial Cancer [Phase 3]
Phase 3 trial evaluating adding a repurposed drug to the combination of lenvatinib plus pembrolizumab in advanced endometrial cancer. The st…