Endometrial Cancer

• CLINICAL_TRIALS trial_result · 2025-04-04
  Clinical Trial Update: Study of XB002 in Subjects With Solid Tumors (JEWEL-101) [Phase 1]

  JEWEL-101 is a Phase 1 trial of XB002 in patients with solid tumors, covering multiple indications. The study has completed.

• CLINICAL_TRIALS trial_result · 2025-04-02
  Clinical Trial Update: TT-10 (PORT-6) and TT-4 (PORT-7) as Single Agents and in Combination in Subjects With Advanced Selected Solid Tumors [Phase 1, Phase 2]

  Clinical trial update for TT-10 and TT-4 (Portage Biotech) exploring single-agent and combination therapy in advanced solid tumors, with rec…

• CLINICAL_TRIALS trial_result · 2025-03-30
  Clinical Trial Update: Adipocytokines in Endometrial Cancer

  A completed clinical trial from the University of Surrey investigated adipocytokines in endometrial cancer with obesity as a related conditi…

• CLINICAL_TRIALS trial_result · 2025-03-28
  Clinical Trial Update: Evaluation of Carboplatin/Paclitaxel/Bevacizumab in the Treatment of Advanced Stage Endometrial Carcinoma [Phase 2]

  Phase 2 clinical trial evaluating the combination of carboplatin, paclitaxel, and bevacizumab in advanced endometrial cancer; the study stat…

• CLINICAL_TRIALS trial_result · 2025-03-28
  Clinical Trial Update: Feasibility of a Patient Directed Tool to Assess Heart Health Among Endometrial Cancer Survivors [NA]

  A completed clinical trial assessing the feasibility of a patient-directed tool to evaluate heart health in endometrial cancer survivors, wi…

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• CLINICAL_TRIALS trial_result · 2025-03-28
  Clinical Trial Update: Bevacizumab and/or Niraparib in Patients With Recurrent Endometrial and/or Ovarian Cancer With ARID1A Mutation [Phase 2]

  Phase 2 trial evaluating bevacizumab and/or niraparib in patients with recurrent endometrial and/or ovarian cancer harboring ARID1A mutation…

• CLINICAL_TRIALS trial_result · 2025-03-26
  Clinical Trial Update: Implementing Enhanced Recovery After Surgery (ERAS) Pathways In Major Gynecologic Oncology Operations In Greece [NA]

  A completed clinical trial conducted in Greece assessed the implementation of Enhanced Recovery After Surgery pathways in major gynecologic …

• CLINICAL_TRIALS trial_result · 2025-03-26
  Clinical Trial Update: A Study of RGX-104 in Patients With Advanced Lung & Endometrial Cancer [Phase 1]

  Phase 1 study of RGX-104 in patients with advanced lung and endometrial cancer has completed.

• CLINICAL_TRIALS trial_result · 2025-03-20
  Clinical Trial Update: Efficacy Assessment of Lenvatinib Associated with Pembrolizumab in Metastatic Endometrial Cancer: a French Multicentric Retrospective Early Access Program-based Study

  This document reports on a retrospective French multicenter study assessing the efficacy of combining lenvatinib with pembrolizumab in metas…

• CLINICAL_TRIALS trial_result · 2025-03-19
  Clinical Trial Update: Enzalutamide, Carboplatin, and Paclitaxel in Treating Patients With Stage III-IV or Recurrent Endometrioid Endometrial Cancer [Phase 2]

  Phase 2 trial evaluating enzalutamide in combination with carboplatin and paclitaxel for stage III-IV or recurrent endometrioid endometrial …

• CLINICAL_TRIALS trial_result · 2025-03-18
  Clinical Trial Update: Testing the Addition of the Immunotherapy Drug Pembrolizumab to the Usual Chemotherapy Treatment (Paclitaxel and Carboplatin) in Stage III-IV or Recurrent Endometrial Cancer [Phase 3]

  Phase 3 trial evaluating adding pembrolizumab to paclitaxel and carboplatin for stage III-IV or recurrent endometrial cancer.

• CLINICAL_TRIALS trial_result · 2025-03-18
  Clinical Trial Update: Testing the Addition of the Immunotherapy Drug Pembrolizumab to the Usual Chemotherapy Treatment (Paclitaxel and Carboplatin) in Stage III-IV or Recurrent Endometrial Cancer [Phase 3]

  Phase 3 trial updating the addition of pembrolizumab to standard chemotherapy (paclitaxel and carboplatin) for stage III-IV or recurrent end…

• CLINICAL_TRIALS trial_result · 2025-03-14
  Clinical Trial Update: Near-Infrared Fluorescence Imaging With Indocyanine Green to Evaluate Bowel Anastomoses in Gynecologic Oncology Surgery [Phase 4]

  This Phase 4 clinical trial update describes using near-infrared fluorescence imaging with indocyanine green to evaluate bowel anastomoses i…

• CLINICAL_TRIALS trial_result · 2025-03-12
  Clinical Trial Update: Effect of Pelvic Radiotherapy on the Intestinal Microbiome and Metabolome

  This completed trial evaluated the effect of pelvic radiotherapy on the intestinal microbiome and metabolome in patients with bladder cancer…

• CLINICAL_TRIALS trial_result · 2025-03-07
  Clinical Trial Update: BP1001-A in Patients With Advanced or Recurrent Solid Tumors [Phase 1]

  This clinical trial update states that BP1001-A is being evaluated in a Phase 1 study for advanced or recurrent solid tumors and is currentl…

• CLINICAL_TRIALS trial_result · 2025-03-06
  Clinical Trial Update: Tazemetostat in Treating Patients With Recurrent Ovarian or Endometrial Cancer [Phase 2]

  This is a Phase 2 clinical trial evaluating tazemetostat for recurrent ovarian or endometrial cancers; the study is currently not recruiting…

• CLINICAL_TRIALS trial_result · 2025-03-06
  Clinical Trial Update: PRospective REgistry of Advanced Stage CancER (PREFER) Patients to Assess Prevalence of Actionable Biomarkers and Driver Mutations to Address Disparities in Precision Medicine

  A completed multicancer registry study (PREFER) assessing the prevalence of actionable biomarkers and driver mutations across advanced cance…

• CLINICAL_TRIALS trial_result · 2025-03-04
  Clinical Trial Update: Study of Copanlisib and Ketogenic Diet [Phase 2]

  A Phase 2 study evaluating copanlisib in combination with a ketogenic diet for follicular lymphoma and endometrial cancer was terminated, wi…

• CLINICAL_TRIALS trial_result · 2025-02-28
  Clinical Trial Update: Study of AK112 in the Treatment of Advanced Gynecological Tumors [Phase 2]

  Phase 2 study of AK112 for advanced gynecologic tumors has been completed, evaluating efficacy in ovarian, cervical, and endometrial cancers…

• CLINICAL_TRIALS trial_result · 2025-02-13
  Clinical Trial Update: Mirvetuximab Soravtansine and Rucaparib Camsylate in Treating Participants With Recurrent Endometrial, Ovarian, Fallopian Tube or Primary Peritoneal Cancer [Phase 1]

  A Phase 1 trial evaluates the combination of mirvetuximab soravtansine and rucaparib camsylate in patients with recurrent gynecologic cancer…

• CLINICAL_TRIALS trial_result · 2025-02-13
  Clinical Trial Update: Tislelizumab for the Treatment of Recurrent Mismatch Repair Deficient Endometrial Cancer [EARLY_Phase 1]

  Early-phase trial update shows termination of a tislelizumab study for recurrent mismatch repair-deficient endometrial cancer.

• CLINICAL_TRIALS trial_result · 2025-02-10
  Clinical Trial Update: A Study of SGN-ALPV in Advanced Solid Tumors [Phase 1]

  Seagen's Phase 1 study of SGN-ALPV in advanced solid tumors has been terminated; the trial evaluated multiple cancers including ovarian, end…

• CLINICAL_TRIALS trial_result · 2025-02-07
  Clinical Trial Update: A Study of SGN-STNV in Advanced Solid Tumors [Phase 1]

  Seagen's Phase 1 study of SGN-STNV in advanced solid tumors has been terminated.

• CLINICAL_TRIALS trial_result · 2025-01-23
  Clinical Trial Update: Validation Study on the Removal of EpCAM-positive Tumour Cells From Blood Collected During Tumour Surgery Using Catumaxomab/Catuvab Device [NA]

  A completed validation trial evaluated removal of EpCAM-positive tumor cells from blood collected during tumor surgery using the Catumaxomab…

• CLINICAL_TRIALS trial_result · 2025-01-17
  Clinical Trial Update: COM701 (an Inhibitor of PVRIG) in Subjects With Advanced Solid Tumors. [Phase 1]

  Phase 1 clinical trial update for COM701, a PVRIG inhibitor, in adults with advanced solid tumors; the study has completed.