Endometrial Cancer

• CLINICAL_TRIALS research · 2026-01-12
  Clinical Trial Update: A Study of SGN-MesoC2 in Advanced Solid Tumors [Phase 1]

  Seagen is conducting a Phase 1 study of SGN-MesoC2 in advanced solid tumors, including non-small cell lung cancer, ovarian cancer, pancreati…

• CLINICAL_TRIALS research · 2026-01-12
  Clinical Trial Update: Dosing Physical Activity Among Older Cancer Survivors Who Experience Chronic Pain: a Micro-randomized Trial [NA]

  A micro-randomized trial testing dosing of physical activity among older cancer survivors with chronic pain is currently recruiting. The tri…

• CLINICAL_TRIALS research · 2026-01-09
  Clinical Trial Update: Remote Home-Based Exercise Program for Strength Training in Endometrial Cancer Survivors in Rural Areas [NA]

  Ongoing trial evaluating a remote home-based strength-training program for endometrial cancer survivors in rural areas, including FIGO grade…

• CLINICAL_TRIALS research · 2026-01-08
  Clinical Trial Update: Predicting Response to Immunotherapy From Analysis of Live Tumor Biopsies

  A clinical trial funded by Elephas is exploring a biomarker-based method to predict response to immunotherapy using live tumor biopsies; the…

• CLINICAL_TRIALS research · 2026-01-08
  Clinical Trial Update: Impact of a Multidisciplinary Assessment in Day Hospitalization Versus Standard Care on the Deployment of Supportive Oncology Care Recommended by the Personalized Post-cancer Plan in Patients at the End of Initial Treatment for Gynecological Ovarian and Endometrial Cancer Endometrial Cancer [NA]

  This clinical trial update describes a study comparing multidisciplinary assessment in day hospitalization versus standard care to implement…

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• CLINICAL_TRIALS research · 2026-01-07
  Clinical Trial Update: A Study of DR-0202 in Patients With Locally Advanced or Metastatic, Relapsed or Refractory Carcinomas [Phase 1]

  DR-0202 is being studied in a Phase 1 trial across multiple locally advanced or metastatic carcinomas; the study is currently recruiting.

• CLINICAL_TRIALS research · 2026-01-07
  Clinical Trial Update: Avelumab and M1774 in ARID1A-mutated Endometrial Cancer [Phase 2]

  Phase 2 trial evaluating Avelumab in combination with M1774 for ARID1A-mutated endometrial cancer is currently recruiting.

• CLINICAL_TRIALS research · 2026-01-07
  Clinical Trial Update: Initial Testing of a Behavioral Intervention About Genetic Services for Families at Risk of Lynch Syndrome [NA]

  An ongoing clinical trial at the University of Alabama at Birmingham is testing a behavioral intervention to improve access to genetic servi…

• CLINICAL_TRIALS research · 2026-01-06
  Clinical Trial Update: A Study of Multiparametric Ultrasound Imaging (mpUS) for People With Endometrial Cancer [NA]

  This is a clinical trial update for a study of multiparametric ultrasound imaging (mpUS) in people with endometrial cancer, currently recrui…

• CLINICAL_TRIALS research · 2026-01-06
  Clinical Trial Update: Comparative Study on the Effect of Diet Interventions on Weight Loss in Overweight Endometrial Cancer Patients Undergoing Fertility-sparing Treatment [NA]

  A clinical trial evaluating whether diet interventions can promote weight loss in overweight endometrial cancer patients undergoing fertilit…

• CLINICAL_TRIALS research · 2026-01-06
  Clinical Trial Update: TSR-042 in Addition to Standard of Care Definitive Radiation for Inoperable Endometrial Cancer [Phase 1]

  Phase 1 trial evaluating TSR-042 (dostarlimab) in addition to standard radiation therapy for inoperable endometrial cancer.

• CLINICAL_TRIALS research · 2026-01-06
  Clinical Trial Update: Phase Ib Study of Avutometinib, Defactinib, and Everolimus in RAS Pathway Mutant Endometrial Cancer [Phase 1]

  A Phase 1b clinical trial is planned to evaluate a triple combination of Avutometinib, Defactinib, and Everolimus in patients with endometri…

• CLINICAL_TRIALS research · 2026-01-06
  Clinical Trial Update: An Automated Personalized Physical Activity Intervention to Improve Immune Function and Clinical Outcomes in Stage II-IV Ovarian, Primary Peritoneal or Fallopian Tube Cancer and Newly Diagnosed Endometrial Cancer, Life on the Go 3 Study [NA]

  Life on the Go 3 is an automated, personalized physical activity program being studied to improve immune function and clinical outcomes in w…

• CLINICAL_TRIALS research · 2025-12-31
  Clinical Trial Update: mTORC1/2 Inhibitor AZD2014 or the Oral AKT Inhibitor AZD5363 for Recurrent Endometrial and Ovarian [Phase 1]

  A Phase 1 study investigating AZD2014 (an mTORC1/2 inhibitor) or AZD5363 (an AKT inhibitor) in recurrent endometrial and ovarian cancers, wi…

• CLINICAL_TRIALS research · 2025-12-30
  Clinical Trial Update: Positron Lymphography Via Intracervical 18F-FDG Injection for Pre-surgical Lymphatic Mapping in Stage IB1 Cervical Cancer and High-grade Endometrial Cancer [Phase 1]

  Phase 1 clinical trial update evaluating intracervical injection of the PET tracer 18F-FDG for pre-surgical lymphatic mapping in stage IB1 c…

• CLINICAL_TRIALS research · 2025-12-30
  Clinical Trial Update: Journey Ahead: Enhancing Coping and Communication for Women Diagnosed With Gynecological Cancer [NA]

  This ClinicalTrials.gov entry describes a Rutgers-led study focused on enhancing coping and communication for women diagnosed with gynecolog…

• CLINICAL_TRIALS research · 2025-12-29
  Clinical Trial Update: Study of Pelvic Hypofractionated Radiotherapy in Endometrial Cancer [Phase 1, Phase 2]

  A Phase 1/2 clinical trial evaluating pelvic hypofractionated radiotherapy for endometrial cancer is currently recruiting.

• CLINICAL_TRIALS research · 2025-12-26
  Clinical Trial Update: Observational Basket Trial to Collect Tissue to Develop and Train a Live Tumor Diagnostic Platform

  An observational basket trial sponsored by Elephas aims to collect tissue to develop and train a live tumor diagnostic platform across multi…

• CLINICAL_TRIALS research · 2025-12-24
  Clinical Trial Update: Sapanisertib and Serabelisib (PIKTOR) With Paclitaxel and a Substudy With an Insulin-Suppressing Diet in Patients With Advanced/Recurrent Endometrial Cancer [Phase 2]

  A Phase 2 clinical trial is evaluating the combination of Sapanisertib and Serabelisib with Paclitaxel, plus a substudy of an insulin-suppre…

• CLINICAL_TRIALS research · 2025-12-23
  Clinical Trial Update: Cervical Cytology DNA Methylation for Endometrial Lesion Screening and Follow-up

  This entry describes a planned clinical trial evaluating cervical cytology DNA methylation as a screening and follow-up tool for endometrial…

• CLINICAL_TRIALS research · 2025-12-22
  Clinical Trial Update: A Study of Dostarlimab in Combination With Carboplatin-paclitaxel in Chinese Participants With Primary Advanced or Recurrent Endometrial Cancer (EC) [Phase 2]

  A Phase 2 study evaluating dostarlimab in combination with carboplatin and paclitaxel in Chinese participants with primary advanced or recur…

• CLINICAL_TRIALS research · 2025-12-22
  Clinical Trial Update: Skeletal Muscle Energy Metabolism in Women With Weight Loss and Ovarian and/or Endometrial Cancer With Weight Loss [NA]

  ClinicalTrials.gov update for NCT03027479, a study on skeletal muscle energy metabolism in women with weight loss and ovarian and/or endomet…

• CLINICAL_TRIALS research · 2025-12-19
  Clinical Trial Update: Clinical Trial Evaluating the Activity of Zanidatamab for the Treatment of Patients With Solid Tumors With an Alteration of the HER2 Gene. [Phase 2]

  A Phase 2 clinical trial is evaluating zanidatamab for solid tumors with HER2 gene alterations across multiple indications and is currently …

• CLINICAL_TRIALS research · 2025-12-19
  Clinical Trial Update: Targeting Inflammation for Endometrial Cancer Prevention

  Mayo Clinic is conducting a trial exploring inflammation-targeting strategies for preventing endometrial cancer; the study is currently acti…

• CLINICAL_TRIALS research · 2025-12-18
  Clinical Trial Update: ctDNA Testing to Inform Standard-of-Care Treatment Decisions in People With Endometrial Cancer [NA]

  This entry describes an ongoing clinical trial evaluating circulating tumor DNA testing to guide standard-of-care treatment decisions for en…