End-stage Renal Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2023-11-09Clinical Trial Update: Efficacy and Safety of Sertraline in the Treatment of Maintenance Hemodialysis Patients With Depression [Phase 4]
Phase 4 trial assessing sertraline for efficacy and safety in maintenance hemodialysis patients with depression has completed.
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FDA approval · 2023-10-17FDA Approved: XPHOZAH 10 MG — Original Application (Ardelyx, Inc.)
FDA approved XPHOZAH (tenapanor) from Ardelyx in its original NDA for the treatment of hyperphosphatemia in adults with chronic kidney disea…
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CLINICAL_TRIALS trial_result · 2023-09-29Clinical Trial Update: Berinert (C1INH) vs Placebo for DGF/IRI [Phase 1, Phase 2]
Phase 1/2 clinical trial comparing Berinert (C1 esterase inhibitor) to placebo for delayed graft function and ischemia-reperfusion injury; t…
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CLINICAL_TRIALS trial_result · 2023-09-29Clinical Trial Update: Study to Compare Safety and Tolerability of AKST1210 Column at 2 Blood Flow Rates in Subjects With ESRD on Hemodialysis [NA]
A completed clinical trial comparing safety and tolerability of AKST1210 at two blood flow rates in subjects with end-stage renal disease on…
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CLINICAL_TRIALS trial_result · 2023-09-28Clinical Trial Update: Efficacy Trial of Fluid Distribution Timetable [Phase 3]
Phase 3 efficacy trial of Fluid Distribution Timetable completed for end-stage renal disease.
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CLINICAL_TRIALS trial_result · 2023-09-28Clinical Trial Update: Myfortic vs. Cellcept in Kidney Transplant Recipients [Phase 2, Phase 3]
Phase 2/3 clinical trial comparing mycophenolate mofetil formulations (Myfortic vs. Cellcept) in kidney transplant recipients has completed.
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CLINICAL_TRIALS trial_result · 2023-09-18Clinical Trial Update: An Effectiveness-Implementation Trial of SPIRIT in ESRD [NA]
The effectiveness-implementation trial SPIRIT in end-stage renal disease (NCT03138564) has completed and posted results as of 2023-09-18.
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CLINICAL_TRIALS trial_result · 2023-08-15Clinical Trial Update: Reducing Arrhythmia in Dialysis by Adjusting the Rx Electrolytes/Ultrafiltration, Study A [NA]
A completed clinical trial from NYU Langone Health investigating electrolyte/ultrafiltration adjustments to reduce arrhythmia in end-stage r…
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CLINICAL_TRIALS trial_result · 2023-07-21Clinical Trial Update: Study to Investigate the Safety of a Drug Called Osocimab at Low and High Doses in Adult Patients With Kidney Failure Requiring Regular Hemodialysis [Phase 2]
Phase 2 trial update evaluating the safety of Osocimab at low and high doses in adults with end-stage renal disease on hemodialysis; results…
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CLINICAL_TRIALS trial_result · 2023-07-03Clinical Trial Update: Factor XI LICA to Reduce Events Such as Heart Attack and Stroke in Patients Whose Kidneys Are no Longer Able to Work as They Should and Require Treatment to Filter Wastes From the Blood: Focus is on the Safety of BAY2976217 and the Way the Body Absorbs, Distributes and Removes the Study Drug [Phase 2]
Phase 2 trial update on BAY2976217 (Factor XI LICA) assessing safety, pharmacokinetics, and distribution in patients with end-stage renal di…
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CLINICAL_TRIALS trial_result · 2023-07-03Clinical Trial Update: Blood Pressure Lowering in Dialysis (BOLD) Trial [Phase 2]
Phase 2 trial investigating blood pressure lowering strategies in patients with end-stage renal disease on dialysis; trial completed with re…
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CLINICAL_TRIALS trial_result · 2023-06-22Clinical Trial Update: Strategies for the Management of Atrial Fibrillation in patiEnts Receiving Dialysis [Phase 2]
Phase 2 trial update on strategies for managing atrial fibrillation in patients receiving dialysis has completed.
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CLINICAL_TRIALS trial_result · 2023-06-18Clinical Trial Update: Eplerenone in Patients Undergoing REnal Transplant (EPURE TRANSPLANT) [Phase 3]
Phase 3 clinical trial update for eplerenone in patients undergoing renal transplant (EPURE TRANSPLANT) for end-stage renal disease.
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CLINICAL_TRIALS trial_result · 2023-06-15Clinical Trial Update: Transplanting Hepatitis C Kidneys Into Negative Kidney Recipients [Phase 1, Phase 2]
Clinical trial update on transplanting hepatitis C–infected kidneys into negative recipients across Phase 1 and Phase 2.
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CLINICAL_TRIALS trial_result · 2023-06-15Clinical Trial Update: Evaluating the Safety and Effectiveness of the InnAVasc Graft for Dialysis Access in Patients With Kidney Failure [NA]
This clinical trial update notes termination of a study evaluating the InnAVasc Graft for dialysis access in patients with kidney failure, w…
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FDA approval · 2023-06-06FDA Approved: SEVELAMER CARBONATE — Supplemental Application (Sanofi-Aventis U.S. LLC)
FDA approved a supplemental application for Sevelamer carbonate from Sanofi-Aventis U.S. LLC, indicating an updated labeling for the product…
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FDA approval · 2023-06-05FDA Approved: DIANEAL LOW CALCIUM WITH DEXTROSE — Supplemental Application (Vantive US Healthcare LLC)
The FDA approved a supplemental application for Dianeal Low Calcium with Dextrose, a peritoneal dialysis solution, submitted by Vantive US H…
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FDA approval · 2023-06-05FDA Approved: DIANEAL PD-2 WITH DEXTROSE — Supplemental Application (Vantive US Healthcare LLC)
The FDA approved a supplemental application for Dianeal PD-2 with Dextrose (a peritoneal dialysis solution) from Vantive US Healthcare LLC.
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CLINICAL_TRIALS trial_result · 2023-06-05Clinical Trial Update: A Pilot Trial of Twice-weekly Versus Thrice-weekly Hemodialysis in Patients With Incident End-stage Kidney Disease [Phase 3]
A Phase 3 pilot trial comparing twice-weekly versus thrice-weekly hemodialysis in incident end-stage kidney disease patients has completed w…
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CLINICAL_TRIALS trial_result · 2023-05-24Clinical Trial Update: SPIRIT for Persons With Dementia and Complex Multimorbidity [NA]
Clinical trial update for SPIRIT study; results completed with posted results.
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FDA approval · 2023-05-10FDA Approved: FOSRENOL — Supplemental Application (Takeda Pharmaceuticals America, Inc.)
The FDA approved a supplemental application for FOSRENOL (lanthanum carbonate) filed by Takeda Pharmaceuticals America, Inc., expanding the …
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FDA approval · 2023-05-10FDA Approved: FOSRENOL — Supplemental Application (Takeda Pharmaceuticals America, Inc.)
FDA approved a supplemental application for Fosrenol (lanthanum carbonate) by Takeda Pharmaceuticals America, Inc.
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CLINICAL_TRIALS trial_result · 2023-04-21Clinical Trial Update: Impact of Black Seed Oil on Hemodialysis Patients [Phase 2]
A Phase 2 clinical trial evaluating the impact of black seed oil on patients with end-stage renal disease undergoing hemodialysis.
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CLINICAL_TRIALS trial_result · 2023-04-20Clinical Trial Update: A Study of Ferric Citrate to Improve Inflammation and Lipid Levels [Phase 4]
Phase 4 trial of ferric citrate in end-stage renal disease assesses inflammation and lipid levels; the study was terminated with results pos…
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CLINICAL_TRIALS trial_result · 2023-04-10Clinical Trial Update: Extended Release Tacrolimus vs. Twice-Daily Tacrolimus [Phase 3]
Phase 3 trial comparing extended-release tacrolimus to twice-daily tacrolimus in renal transplant patients; results posted after completion.