End-stage Liver Disease
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CLINICAL_TRIALS trial_result · 2018-07-20Clinical Trial Update: Outcomes of Liver Transplantation in Low Weight Children After Reducing the Lateral Segment of a Living Donor, Adapting the Shape and Size of the Graft to the Needs of the Recipient
A completed clinical trial evaluating liver transplantation in very low-weight children using hyper-reduced grafts from living donors, with …
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CLINICAL_TRIALS trial_result · 2018-05-16Clinical Trial Update: Myfortic, Prograf, and Corticosteroids in de Novo Liver Transplantation
Completed clinical trial evaluating immunosuppression regimens using Myfortic, Prograf, and corticosteroids in de novo liver transplantation…
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CLINICAL_TRIALS trial_result · 2018-05-11Clinical Trial Update: The Feasibility of a Prehabilitation Program in the Liver Transplant Population at Barnes-Jewish Hospital [NA]
A completed feasibility study evaluating a prehabilitation program for patients with end-stage liver disease undergoing liver transplantatio…
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CLINICAL_TRIALS research · 2018-04-26Clinical Trial Update: French HIV-HBV Cohort
This entry notes an ongoing French HIV-HBV cohort clinical trial sponsored by Institut de Médecine et d'Epidémiologie Appliquée, studying pa…
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CLINICAL_TRIALS trial_result · 2018-04-18Clinical Trial Update: Sirolimus-based Immunosuppression Treatment Regimen for Liver Transplantation [Phase 2, Phase 3]
This document reports on a phase 2/phase 3 clinical trial evaluating a sirolimus-based immunosuppression regimen for liver transplantation.
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CLINICAL_TRIALS trial_result · 2018-03-07Clinical Trial Update: Evaluation of the Safety of Octaplas™ Versus Plasma in Patients Undergoing Orthotopic Liver Transplantation
Clinical trial update evaluating the safety of Octaplas compared with standard plasma in patients undergoing orthotopic liver transplantatio…
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CLINICAL_TRIALS trial_result · 2018-02-28Clinical Trial Update: Albumin, COP and Endothelial Damage in Patients With ESLD Undergoing OLT
Clinical trial update examining albumin effects on colloid osmotic pressure and endothelial damage in patients with end-stage liver disease …
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CLINICAL_TRIALS trial_result · 2017-07-05Clinical Trial Update: A Comparison of Propofol Based Total Intravenous Anesthesia and Desflurane Based Balanced Anesthesia on Hepatic Protection During Living-donor Liver Transplantation [Phase 4]
This Phase 4 clinical trial update reports a completed study comparing propofol-based total intravenous anesthesia with desflurane-based bal…
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CLINICAL_TRIALS trial_result · 2017-03-23Clinical Trial Update: TOP-Study (Tacrolimus Organ Perfusion): Treatment of Ischemia Reperfusion Injury in Marginal Organs With an ex Vivo Tacrolimus Perfusion [Phase 2, Phase 3]
The TOP-Study evaluated ex vivo tacrolimus perfusion to treat ischemia-reperfusion injury in marginal liver grafts (Phase 2/3). The trial st…
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CLINICAL_TRIALS other · 2017-01-25Clinical Trial Update: Factors Associated With End Stage Liver Disease
This clinical trial update notes that NCT01846819, sponsored by NYU Langone Health, investigating factors associated with end-stage liver di…
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CLINICAL_TRIALS trial_result · 2017-01-24Clinical Trial Update: Efficacy, Safety and Tolerability of Everolimus in Combination With Reduced Exposure Cyclosporine or Tacrolimus in Paediatric Liver Transplant Recipients. [Phase 3]
A Phase 3 trial evaluating Everolimus with reduced exposure to cyclosporine or tacrolimus in pediatric liver transplant recipients, focusing…
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: Study of Liver Transplant For End-Stage Liver Disease Caused By Chronic Hepatitis C Infection [Phase 4]
This Clinical Trial Update reports results from a Phase 4 study evaluating liver transplantation for end-stage liver disease caused by chron…
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CLINICAL_TRIALS research · 2017-01-04Clinical Trial Update: A Study of Retrograde rEperfusion in Dbd Donor LIver Transplantation [NA]
This clinical trial update describes a study of retrograde reperfusion in donation-after-brain-death donor liver transplantation, sponsored …
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CLINICAL_TRIALS trial_result · 2016-12-15Clinical Trial Update: Perioperative Evaluation of Terlipressin Infusion During Living Donor Liver Transplantation on Incidence of Acute Kidney [Phase 4]
A Phase 4 trial evaluated perioperative terlipressin infusion during living donor liver transplantation to assess its effect on the incidenc…
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CLINICAL_TRIALS trial_result · 2016-12-08Clinical Trial Update: Gradual Withdrawal of Immune System Suppressing Drugs in Patients Receiving a Liver Transplant [Phase 2]
A Phase 2 trial evaluating gradual withdrawal of immunosuppressive therapy in liver transplant recipients; results have been posted.
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CLINICAL_TRIALS withdrawal · 2016-10-04Clinical Trial Update: Study of Peripheral Tissue Oxygenation in End-stage Liver Disease Patients During Liver Transplantation
This clinical trial investigating peripheral tissue oxygenation in end-stage liver disease patients during liver transplantation has been wi…
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CLINICAL_TRIALS trial_result · 2016-07-11Clinical Trial Update: Psychosocial Risks in Liver Transplant Recipients
This clinical trial update summarizes the psychosocial risks identified in liver transplant recipients with end-stage liver disease. The stu…
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CLINICAL_TRIALS trial_result · 2016-03-22Clinical Trial Update: Spray Diathermy Versus Harmonic Scalpel Technique for Hepatic Parenchymal Transection [EARLY_Phase 1]
A Phase 1 trial comparing spray diathermy to the harmonic scalpel for hepatic parenchymal transection in end-stage liver disease has complet…
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CLINICAL_TRIALS trial_result · 2015-07-23Clinical Trial Update: Antinociceptive Modalities on Ischemia Reperfusion Injury
The clinical trial NCT01932918 evaluating antinociceptive modalities for ischemia-reperfusion injury has completed.
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CLINICAL_TRIALS trial_result · 2015-04-14Clinical Trial Update: Transplant and Addiction Project (TAP) - 1 [Phase 1, Phase 2]
Update on the Transplant and Addiction Project (TAP), a Phase 1/Phase 2 clinical trial for substance-related disorders in patients with end-…
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CLINICAL_TRIALS trial_result · 2014-12-16Clinical Trial Update: CNI-free de Novo Protocol in Patients Undergoing Liver Transplantation With Renal Impairment [Phase 3]
Phase 3 clinical trial update for a calcineurin inhibitor-free de novo immunosuppression protocol in liver transplant patients with renal im…
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CLINICAL_TRIALS research · 2014-12-16Clinical Trial Update: Analysis of Respiratory System Mechanics and Inflammatory Response During Orthotopic Liver Transplantation (SPPLIT Trial)
The SPPLIT trial analyzes respiratory system mechanics and the inflammatory response during orthotopic liver transplantation in patients wit…
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CLINICAL_TRIALS research · 2014-12-04Clinical Trial Update: The Efficacy of the Administration of Fibrinogen in Liver Transplantation [Phase 3]
A Phase 3 trial is evaluating whether administering fibrinogen during liver transplantation reduces intraoperative bleeding; the current sta…
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CLINICAL_TRIALS trial_result · 2014-10-15Clinical Trial Update: Health Related Quality of Life Assessment In Egyptian Recipients After Living Donor Liver Transplantation
This clinical trial update reports on health-related quality of life outcomes in Egyptian recipients after living-donor liver transplantatio…
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CLINICAL_TRIALS trial_result · 2014-09-16Clinical Trial Update: Improving Clinician Communication Skills (ICCS) [Phase 3]
Phase 3 trial evaluating a program to improve clinician communication skills has completed. The ICCS study is sponsored by the University of…