Emphysema
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-10-19Clinical Trial Update: Airway Clearance for Prevention of Chronic Obstructive Pulmonary Disease (COPD) Exacerbation [Phase 4]
Phase 4 clinical trial updates airway clearance for COPD prevention; study completed with posted results.
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CLINICAL_TRIALS trial_result · 2018-09-25Clinical Trial Update: LVRC IDE Crossover Study (Crossover From IDE Trial CLN0009) [NA]
A crossover trial update for LVRC IDE/Crossover study in emphysema has terminated; results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-07-13Clinical Trial Update: Phase 2 Study of Ex-vivo Perfusion and Ventilation of Lungs to Assess Transplant Suitability [NA]
Phase 2 trial evaluating ex-vivo lung perfusion and ventilation to assess transplant suitability, sponsored by the University of North Carol…
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CLINICAL_TRIALS trial_result · 2018-06-18Clinical Trial Update: Evaluating Genetic Factors That May Contribute to Elastin Function and the Development of Chronic Obstructive Pulmonary Disease
A completed clinical trial from Washington University School of Medicine investigated genetic factors affecting elastin function and their p…
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CLINICAL_TRIALS trial_result · 2018-05-04Clinical Trial Update: Biomarkers and Genetic Factors Related to Emphysema
This completed clinical trial investigated biomarkers and genetic factors associated with emphysema, a form of chronic obstructive pulmonary…
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CLINICAL_TRIALS trial_result · 2018-04-20Clinical Trial Update: Ex-vivo Perfusion and Ventilation of Lungs Recovered From Non-Heart-Beating Donors to Assess Transplant Suitability [NA]
This completed clinical trial evaluated ex-vivo perfusion and ventilation of donor lungs recovered from non-heart-beating donors to assess t…
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CLINICAL_TRIALS trial_result · 2018-04-17Clinical Trial Update: Clinical Trial to Evaluate the Safety and Effectiveness of the IBV® Valve System for the Treatment of Severe Emphysema [NA]
Clinical trial update on the safety and effectiveness of the IBV Valve System for the treatment of severe emphysema; the study has completed…
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CLINICAL_TRIALS withdrawal · 2018-03-08Clinical Trial Update: Evaluating the Clinical Effectiveness of 3D Printing for a Patient-specific Silicone Stent Airway Implant [NA]
The clinical trial evaluating 3D-printed silicone airway stent for COPD and emphysema has been withdrawn.
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CLINICAL_TRIALS trial_result · 2017-07-27Clinical Trial Update: The Effectiveness of Roflumilast in Improving Mucociliary Clearance in Patients With COPD and Chronic Bronchitis [Phase 4]
A Phase 4 clinical trial update evaluating the effectiveness of roflumilast in improving mucociliary clearance in patients with COPD and chr…
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CLINICAL_TRIALS trial_result · 2017-06-27Clinical Trial Update: Lung Volume Reduction Coil Treatment in Patients With Emphysema (RENEW) Study [NA]
Clinical trial update for the RENEW study of lung volume reduction coil treatment in emphysema; the study is terminated with results posted …
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CLINICAL_TRIALS research · 2017-06-27Clinical Trial Update: A Safety and Feasibility Study of Re-treating Patients With Severe Emphysema With the RePneu LVRC System. [NA]
This update covers a completed safety and feasibility study evaluating re-treatment with the RePneu LVRC System in patients with severe emph…
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CLINICAL_TRIALS trial_result · 2017-05-04Clinical Trial Update: Study Comparing Simulect Plus Standard Immunosuppression to Standard Immunosuppression Alone for the Prevention of Acute Rejection and Bronchiolitis Obliterans in Lung Transplant [Phase 3]
Phase 3 randomized trial comparing Simulect (basiliximab) plus standard immunosuppression to standard immunosuppression alone for prevention…
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CLINICAL_TRIALS withdrawal · 2017-05-02Clinical Trial Update: Lung Volume Reduction Coils for Emphysema in Alpha-1 Antitrypsin Deficiency [NA]
A ClinicalTrials.gov study on Lung Volume Reduction Coils for emphysema in Alpha-1 antitrypsin deficiency has been withdrawn.
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CLINICAL_TRIALS trial_result · 2017-04-25Clinical Trial Update: Efficacy of Losartan in Preventing Progression of COPD [Phase 4]
Phase 4 clinical trial update reporting the completion and posted results of evaluating losartan for preventing progression of chronic obstr…
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CLINICAL_TRIALS research · 2017-03-29Clinical Trial Update: Evaluating Genes in Sputum to Measure Drug Response in COPD [NA]
A National Jewish Health-sponsored COPD trial evaluating sputum gene expression as a biomarker for drug response has been terminated.
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CLINICAL_TRIALS trial_result · 2017-02-01Clinical Trial Update: Electrical Impedance Imaging of Patients on Mechanical Ventilation
Completed clinical trial evaluating electrical impedance imaging in mechanically ventilated patients to characterize chest conditions such a…
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CLINICAL_TRIALS research · 2017-01-04Clinical Trial Update: Pulmonary Hemodynamics in Patients With Severe Emphysema Pre and Post BLVR
This clinical trial update examines pulmonary hemodynamics in patients with severe emphysema before and after bronchoscopic lung volume redu…
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CLINICAL_TRIALS research · 2017-01-02Clinical Trial Update: Spiration Valve System 9 mm European Post Market Evaluation Study
This is a European post-market evaluation study of the Spiration Valve System 9 mm for emphysema; the current status of the study is unknown…
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CLINICAL_TRIALS trial_result · 2016-11-02Clinical Trial Update: TESRA: (Treatment of Emphysema With a Gamma-Selective Retinoid Agonist) [Phase 2]
Phase 2 TESRA trial evaluating a gamma-selective retinoid agonist for emphysema has completed.
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CLINICAL_TRIALS research · 2016-10-21Clinical Trial Update: Acute Dyspnea After Use of Non-invasive Ventilation in COPD and Emphysema (Deventilation Syndrome)
This clinical trial update notes an event of acute dyspnea after non-invasive ventilation in patients with COPD and emphysema (deventilation…
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CLINICAL_TRIALS withdrawal · 2016-08-04Clinical Trial Update: Perforomist Versus Foradil Evaluated by Inspiratory Capacity and High Resolution Computed Tomography (HRCT) [Phase 4]
A Phase 4 trial comparing Perforomist to Foradil in COPD patients, evaluated by inspiratory capacity and high-resolution CT, has been withdr…
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CLINICAL_TRIALS trial_result · 2016-07-12Clinical Trial Update: Extension Study of Zemaira® i.v. Administration in Subjects With Emphysema Due to alpha1-proteinase Inhibitor Deficiency. [Phase 4]
This is a Phase 4 extension study of intravenous Zemaira in subjects with emphysema due to alpha-1 antitrypsin deficiency; results from the …
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CLINICAL_TRIALS research · 2016-07-06Clinical Trial Update: Endobronchial Valve in Patients With Heterogeneous Emphysema [NA]
Clinical trial update on the Endobronchial Valve for heterogeneous emphysema; the current status of the trial is unknown.
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FDA approval · 2016-06-09FDA Approved: COMBIVENT RESPIMAT — Supplemental Application (Boehringer Ingelheim Pharmaceuticals, Inc.)
FDA approved a supplemental application for Combivent Respimat (ipratropium bromide and albuterol) from Boehringer Ingelheim Pharmaceuticals…
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CLINICAL_TRIALS trial_result · 2016-05-13Clinical Trial Update: Emphysema: Physiologic Effects of Nutritional Support [Phase 2]
Phase 2 trial update assessing the physiologic effects of nutritional support in emphysema.